Mediator Subunit16 Induces BnMED25- and BnWRKY33-Activated Defense Signaling to Confer Resistance.

The plant mediator is a highly conserved protein complex that interacts with transcription factors (TFs) and RNA polymerase II (RNAP II) to relay regulatory information during transcription. Plant immune response is one of the biological processes that is orchestrated by this regulatory mechanism. s, an important oil crop, is severely attacked by a devastating disease Sclerotinia stem rot.

Identification and investigation of the vibrational properties of crystalline and co-amorphous drugs with Raman and terahertz spectroscopy.

Co-amorphous drugs have shown significant potential in improving the stability and bioavailability compared with single neat amorphous drugs. Here, we explored the molecular interactions of cimetidine, naproxen, indomethacin and their binary co-amorphous mixtures via Raman and terahertz (THz) spectroscopy. We used quench-cooled method to prepare the neat amorphous drugs and their binary co-amorphous mixtures and tested their thermodynamic properties through differential scanning calorimetry (DSC).