Publications by authors named "Xuan-Hao Lin"

Biochar, produced as a by-product of pyrolysis/gasification of waste biomass, shows great potential to reduce the environment impact, address the climate change issue, and establish a circular economy model. Despite the promising outlook, the research on the benefits of biochar remains highly debated. This has been attributed to the heterogeneity of biochar itself, with its inherent physical, chemical and biological properties highly influenced by production variables such as feedstock types and treating conditions.

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Terephthalic acid (TA) is toxic and known as an endocrine disruptor. In this paper, the photocatalytic degradation of TA using sulfated titanium dioxide SO4(2-)/TiO2 photocatalysts was investigated. The photocatalysts were prepared by sol-gel method and characterized by XRD, SEM, BET, ICP/MS and spectroscopic methods.

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Fascin-1 (FSCN1) is an actin-bundling protein that induces cell membrane protrusions, increases cell motility, and is overexpressed in various human epithelial cancers, including esophageal squamous cell carcinoma (ESCC). We analyzed various protein-protein interactions (PPI) of differentially-expressed genes (DEGs), in fascin knockdown ESCC cells, to explore the role of fascin overexpression. The node-degree distributions indicated these PPI sub-networks to be characterized as scale-free.

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The lipocalin proteins (lipocalins) are a large family of small proteins characterized by low sequence similarity and highly conserved crystal structures. Lipocalins have been found to play important roles in many human diseases. For this reason, a systemic analysis of the molecular properties of human lipocalins is essential.

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Recently photocatalytic treatment of municipal reverse osmosis concentrate (ROC) has drawn increasing attention due to its relatively high efficiency and low cost. However, photocatalytic reactions by commercially available TiO₂ are not able to degrade fluorosurfactants in the ROC sample due to the absence of photoreactive groups in these compounds. Here we investigated adsorption and coagulation methods and their efficiencies in removing fluorosurfactants.

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Layered double oxide hollow spheres (LDO-HSs) were synthesized and employed as a dissolvable sorbent in dispersive solid-phase extraction (DSPE) to extract eleven United States Environmental Protection Agency's priority phenols from aqueous samples. With their higher specific surface area, LDO-HSs showed much higher extraction efficiency than normal layered double hydroxides and layered double oxides. The entire extraction process was accomplished in a syringe.

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NGAL (neutrophil gelatinase-associated lipocalin) is a novel cancer-related protein involves multiple functions in many cancers and other diseases. We previously overexpressed NGAL to analyze its role in esophageal squamous cell carcinoma (ESCC). In this study, a protein-protein interaction (PPI) was constructed and the shortest paths from NGAL to transcription factors in the network were analyzed.

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Caloric restriction (CR) is known to increase the number of primordial follicles and prolong the reproductive life span. However, how CR modulates follicular development is not well understood. In the present study, we examined the effects of CR on follicular development in rats and investigated the underlying mechanism.

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Article Synopsis
  • * Results showed that rapamycin treatment resulted in a significantly higher number of primordial follicles compared to the control group, indicating its potential to preserve follicle reserves.
  • * Analysis revealed that rapamycin reduces certain signals (mTOR and p70S6K) while increasing sirtuin proteins (SIRT1 and SIRT6), suggesting it helps prevent the transition of primordial follicles to developing ones.
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Article Synopsis
  • The study investigates how caloric restriction (CR) affects the reproductive lifespan in rats and the role of insulin-like growth factor-1 (IGF-1) in this process.
  • Results show that CR lowers IGF-1 levels, leading to decreases in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and estrogen (ESG) levels, while promoting the survival of primordial and surviving follicles.
  • Immunohistochemical analysis reveals that IGF-1 is mainly found in the cytoplasm of healthy granulosa cells but absent in deteriorating follicles, indicating that CR may enhance female reproductive capacity by regulating IGF-1 levels and subsequent hormone release.
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Background And Aims: Caloric restriction (CR) extends mammals' lifespans and suppresses ovary development. Sirtuins are involved in these mechanisms. If, and to what extent CR affects ovarian lifespan and follicle development is largely unknown.

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