Publications by authors named "Xuan-Ge Chen"
Article Synopsis
- The study aimed to report the outcomes of endoscopy-assisted vitrectomy (EAV) in patients suffering from chronic hypotony due to severe eye trauma or previous vitrectomy procedures.
- A total of seven male patients (mean age 45) underwent EAV, with various surgical techniques applied, and their intraocular pressure (IOP) and best-corrected visual acuity (BCVA) were measured before and after the surgery.
- Results showed a significant improvement in IOP and BCVA in most patients, suggesting that endoscopy is a promising technique for managing chronic hypotony after eye trauma.
Aim: To evaluate the protective effects of lipoic acid-niacin (N2L) dimers against blue light (BL)-induced oxidative damage to human retinal pigment epithelium (hRPE) cells
Methods: hRPE cells were divided into a control group (CG), a BL group, an N2L plus BL irradiation group, an α-lipoic acid (ALA) plus BL group, an ALA-only group, and an N2L-only group. hRPE cellular viability was detected by performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) bromide assays, and apoptosis was evaluated by annexin-V-PE/7-AAD staining followed by flow cytometry. Ultrastructural changes in subcellular organelles were observed by transmission electron microscopy.