[Primary culture of human malignant meningioma cells and its intracranial orthotopic transplantation in nude mice].

Objective: To obtain stable primary cultures of human malignant meningioma cells and establish an intracranial in-situ tumor model in nude mice.

Methods: Ten surgical specimens of highly suspected malignant meningioma were obtained with postoperative pathological confirmation. Primary malignant meningioma cells were cultured from the tissues using a modified method and passaged.