A novel proceduralized donor liver back-table preparation technique minimizes hemorrhage following liver implantation in orthotropic liver transplantation.

Background: Intraoperative hemorrhage is one of the major complications of orthotopic liver transplantation (OLT) and is mainly caused by technical difficulties of the surgical procedure besides primary liver diseases. The present study aimed to evaluate the feasibility and clinical effects of a novel proceduralized donor liver back-table preparation (DLBTP) technique for use in OLT.

Methods: This retrospective study was conducted between January 2018 and June 2020 based on patients who had undergone OLT.

A Novel Preoperative Classification System for Selecting Suitable Surgeries in Liver Transplant Patients with Portal Vein Cavernous Transformation.

Background: To evaluate the new preoperative Changgung classification (CC) system of portal vein thrombosis (PVT) in choosing suitable operative procedures to reconstruct portal veins during liver transplantation (LT) in patients with portal vein cavernous transformation (PVCT).

Methods: This retrospective observational study analyzed data from allograft LTs performed for various liver diseases.

Results: The study included 22 males and 4 females with LT indications comprising cirrhosis ( = 9), hepatocellular carcinoma ( = 12), PVCT ( = 2), liver failure from fulminant hepatitis B ( = 1), dysfunction of transplanted liver ( = 1), and chronic rejection of transplanted liver ( = 1).

Portable ratiometric fluorescence detection of Cuand thiram.

Food contaminants pose a danger to human health, but rapid, sensitive and reliable food safety detection methods can offer a solution to this problem. In this study, an optical fiber ratiometric fluorescence sensing system based on carbon dots (CDs) and o-phenylenediamine (OPD) was constructed. The ratiometric fluorescence response of Cuand thiram was carried out by the fluorescence resonance energy transfer (FRET) between CDs and 2,3-diaminophenazine (ox-OPD, oxidized state o-phenylenediamine).

Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review.

Kudzu root (Pueraria lobate (Willd.) Ohwi, KR) is an edible plant with rich nutritional and medicinal values. Over the past few decades, an ample variety of biological effects of Pueraria isoflavone have been evaluated.

Location and extent of cavernous transformation of the portal vein dictates different visceral side revascularization in Meso-Rex bypass.

Background: As an emerging standard of care for portal vein cavernous transformation (PVCT), Meso-Rex bypass (MRB) has been complicated and variated. The study aim was to propose a new classification of PVCT to guide MRB operations.

Methods: Demographic data, the extent of extrahepatic PVCT, surgical methods for visceral side revascularization, intraoperative blood loss, operating time, changes in visceral venous pressure before and after MRB, postoperative complications and the condition of bypass vessels after MRB were extracted retrospectively from the medical records of 19 patients.

Synergistic effect of indium doping and chlorine surface passivation on CsPbI perovskite quantum dots for deep-red light-emitting devices.

Deep-red CsPbI perovskite quantum dots (PeQDs) are essential for high-efficiency perovskite light-emitting diodes (PeLEDs) because of their high color purity and high photoluminescence quantum yield (PLQY). The synergetic strategy of indium (In) doping and chlorine (Cl) surface passivation not only partially replaced Pb ions with the smaller ionic In but also filled I vacancies by Cl on the surface, maintaining the humidity stability for more than 24 days and yielding excellent PLQY. Benefiting from this synergetic strategy, deep-red (approximately at 683 nm) CsPbI PeLEDs showed a maximum luminance and external quantum efficiency (EQE) of 311 cd m and 8.

The Dislocation- and Cracking-Mediated Deformation of Single Asperity GaAs during Plowing Using Molecular Dynamics Simulation.

This work simulates the plowing process of a single asperity GaAs by diamond indenter using molecular dynamics simulations. The deformation mechanism of asperity GaAs is revealed by examining the topography evolution and stress state during the plowing. This work also investigates the origin of the influence of asperity size, indenter radius and plow depth on the deformation of the asperity GaAs.

Modified Meso-Rex bypass with umbilical vein recanalization and intra-operative stenting.

Purpose: The aim of the study was to evaluate the usefulness of a novel modified Meso-Rex bypass surgical technique with umbilical vein recanalization and intra-operative stenting to treat portal vein cavernous transformation.

Methods: In total, 13 portal vein cavernous transformation patients underwent Meso-Rex bypass surgery, consisting of bypass grafts between the superior mesenteric vein (SMV) and the recess of Rex as well as through the ligamentum teres hepatis without stent implantation (Group A, n = 9) and umbilical vein recanalization with intra-operative stent implantation (Group B, n = 4).

Results: In Group A, the bypass diameter was 0-6 mm (median 3 mm) and blood flow velocity 25-115 cm/s (median 72 cm/s) 1 month after Meso-Rex bypass surgery, with open bypass times of 0-67 months (median 6 months); 6 patients in this group developed postoperative Meso-Rex bypass occlusions.

Augmented Reality-Assisted Pancreaticoduodenectomy with Superior Mesenteric Vein Resection and Reconstruction.

Introduction: Pancreaticoduodenectomy (PD) with superior mesenteric vein (SMV) reconstruction are often required to achieve complete (R0) resection for pancreatic head cancer (PHC) with tumor invasion of the SMV. Augmented reality (AR) technology can be used to assist in determining the extent of SMV involvement by superimposing virtual 3-dimensional (3D) images of the pancreas and regional vasculature on the surgical field.

Materials And Methods: Three patients with PHC and tumor invasion of the SMV underwent AR-assisted PD with SMV resection and reconstruction following preoperative computed tomography scanning.

Confinement Effect of Graphene Interface on Phase Transition of -Eicosane: Molecular Dynamics Simulations.

Phase change materials (PCMs) are widely used in thermal management and energy storage systems. Investigations on the thermophysical properties enhancement of organic PCMs by introducing carbon-based frameworks have received much attention in recent years. Studies of the phase transition in nanoconfinement are still in controversy with divergent opinions among researchers.

Core-Shell Au@Metal-Organic Frameworks for Promoting Raman Detection Sensitivity of Methenamine.

Abuse of methenamine in foodstuff is harmful to the health of people. Routine methods recommended by the national standard are indirect assays with complicated pretreatment of samples or less sensitivity. In this work, core-shell Au nanoparticles@inositol hexaphosphate@MIL-101(Fe) nanoparticles, designated as Au@MIL-101, are successfully synthesized by layer-by-layer assembly.

Cholesterol polyps in the distal common bile duct: a case report.

Rationale: Cholesterol polyps are rare in the common bile duct and difficult to diagnose.

Patient Concerns: The small polypoid lesions often go undetected when using routine imaging methods, such as ultrasonography.

Diagnoses: We treated a patient with cholesterol polyps in the common bile duct.

HPLC method for determination of SN-38 content and SN-38 entrapment efficiency in a novel liposome-based formulation, LE-SN38.

A simple HPLC method was developed for quantification of SN-38, 7-ethyl-10-hydroxycamptothecin, in a novel liposome-based formulation (LE-SN38). The chromatographic separation was achieved on an Agilent Zorbax SB-C18 (4.6 mmx250 mm, 5 microm) analytical column using a mobile phase consisting of a mixture of NaH2PO4 (pH 3.

Development and characterization of a novel Cremophor EL free liposome-based paclitaxel (LEP-ETU) formulation.

Taxol is a marketed product for the treatment of ovarian, breast, non-small cell lung cancer and AIDS-related Kaposi's Sarcoma. It is thus far one of the most effective anticancer drugs available on the market. However, paclitaxel is only sparingly soluble in water and therefore, intravenous administration depends on the use of the non-ionic surfactant Cremophor EL (polyethoxylated castor oil) to achieve a clinically relevant concentrated solution.

Development and characterization of a novel liposome-based formulation of SN-38.

SN-38, 7-ethyl-10-hydroxycamptothecin, is the active metabolite of Irinotecan (CPT-11), a topoisomerase I inhibitor commercially available as Camptosar. SN-38 is approximately 200-2000-fold more cytotoxic than CPT-11. Despite its promising anticancer potential, SN-38 thus far has not been used as an anticancer drug due to its poor solubility in any pharmaceutically acceptable solvents.