Publications by Xuan K Lim

Publications by authors named "Xuan K Lim"

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Targeting aging with urolithin A in humans: A systematic review.

Ajla Hodzic Kuerec Xuan K Lim Anderson Ly Khoo Elena Sandalova Lihuan Guan

Ageing Res Rev

September 2024

Urolithin A (UA) is a gut metabolite derived from ellagic acid. This systematic review assesses the potential geroprotective effect of UA in humans. In five studies including 250 healthy individuals, UA (10-1000 mg/day) for a duration ranging from 28 days to 4 months, showed a dose-dependent anti-inflammatory effect and upregulated some mitochondrial genes, markers of autophagy, and fatty acid oxidation.

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