High level of H3K4 tri-methylation modification predicts poor prognosis in esophageal cancer.

: An increase in the trimethylation of lysine 4 of histone 3 (H3K4me3) has been reported to be involved in the development of several types of tumors. However, the level and role of H3K4me3 in human esophageal cancer (HEC) remain unknown. Here, we assessed the role and clinical significance of H3K4me3 in HEC.

Long non-coding RNA PSMA3-AS1 promotes malignant phenotypes of esophageal cancer by modulating the miR-101/EZH2 axis as a ceRNA.

Backgrounds: Emerging evidences has demonstrated that dysregulation of long non-coding RNAs (lncRNAs) is critically involved in esophageal squamous cell carcinoma (ESCC) progression. However, the function of lncRNA PSMA3-AS1 in ESCC is unclear. Therefore, we aimed to explore the functions and potential mechanisms of PSMA3-AS1 in ESCC cells progression.

Prevalence and risk factors associated with chronic kidney disease in a Zhuang ethnic minority area in China.

Aim: Numerous studies have examined and reported a high prevalence of chronic kidney disease (CKD) in the general population in various countries including China. However, the situation may be different in undeveloped rural minority regions in China because of China's economic diversity. The aim of the present study was to estimate the prevalence of CKD and to analyze its associated factors in a Zhuang ethnic minority area in Southwest China.

[An epidemiology study on hypertension in the Zhuang nationality village from the Guangxi Zhuang Autonomous Region].

Objective: To observe the risk factors and prevalence status of hypertension at the Guangxi Zhuang-rural region.

Methods: Through cross-sectional survey, Xinlan village (Ethnic-Zhuang tribe village) in Liangqing District of Nanning was chosen as survey site. Select Zhuang-ethnic villagers (age ≥ 18 years, living time ≥ 6 months per year) as survey subjects.