Circ-0001313/miRNA-510-5p/AKT2 axis promotes the development and progression of colon cancer.

Circular RNAs (circRNAs) have recently emerged as novel and potentially promising therapeutic targets in a serious of cancers. However, the expression pattern and biological function of circRNAs in colon cancer remain largely elusive. This study firstly analyzed circRNA microarray of colon cancer and selected circ-0001313 as the study object.

Comparative study of laparoscopic-assisted and open total gastrectomy for Siewert Types II and III adenocarcinoma of the esophagogastric junction.

Background: The potential advantages of laparoscopic-assisted total gastrectomy (LATG) compared with open total gastrectomy (OTG) for Siewert Types II and III adenocarcinoma of the esophagogastric junction (AEJ) are not very clear. Thus, the aim of this study was to investigate the surgical outcomes and potential advantages of LATG for Siewert Types II and III AEJ.

Methods: The clinical data of 75 patients (32 for LATG and 43 for OTG) with Siewert II or III AEJ from August 2009 to February 2014 were analyzed retrospectively.

[Analysis of mortality rate of stomach cancer and its trend in twenty years in China].

Objective: To analyze and predict the trend in mortality rate of stomach cancer in twenty years in China.

Methods: Stomach cancer mortality data collected from the China national survey over the period 1970s - 1990s for the cause of death were analyzed.

Results: The adjusted mortality rate of stomach cancer in 1990s increased by 11.