Mechanism of ELL-associated factor 2 and vasohibin 1 regulating invasion, migration, and angiogenesis in colorectal cancer.

Background: As a novel endogenous anti-angiogenic molecule, vasohibin 1 (VASH1) is not only expressed in tumor stroma, but also in tumor tissue. Moreover, studies have shown that VASH1 may be a prognostic marker in colorectal cancer (CRC). Knockdown of VASH1 enhanced transforming growth factor-β1 (TGF-β1)/Smad3 pathway activity and type I/III collagen production.

Assessment of the effects of induced anisometropia on binocularity with glasses-free 3D technique.

Aim: To assess the effect of experimentally induced anisometropia on binocularity in normal adults with glasses-free three-dimensional (3D) technique.

Methods: Totally 54 healthy medical students with normal binocularity in the cross-sectional study were enrolled. Anisometropia was induced by placing trail lenses over the right eye, in 0.

Collectin11 and Complement Activation in IgA Nephropathy.

Background And Objectives: IgA nephropathy is the most common primary GN worldwide. Previous research demonstrated that collectin11, an initiator of the complement lectin pathway, was involved in both AKI and chronic tubulointerstitial fibrosis. Here, we investigated the potential role of collectin11 in the pathogenesis of IgA nephropathy.

Constraint-Induced Movement Therapy Promotes Neural Remodeling and Functional Reorganization by Overcoming Nogo-A/NgR/RhoA/ROCK Signals in Hemiplegic Cerebral Palsy Mice.

. Little is known about the induction of functional and brain structural reorganization in hemiplegic cerebral palsy (HCP) by constraint-induced movement therapy (CIMT). .

The potential role of mechanically sensitive ion channels in the physiology, injury, and repair of articular cartilage.

Biomechanical factors play an extremely important role in regulating the function of articular chondrocytes. Understanding the mechanical factors that drive chondrocyte biological responses is at the heart of our interpretation of cascade events leading to changes in articular cartilage osteoarthritis. The mechanism by which mechanical load is transduced into intracellular signals that can regulate chondrocyte gene expression remains largely unknown.

MicroRNA-21-5p participates in IgA nephropathy by driving T helper cell polarization.

Background: Previous studies have revealed abnormal lymphocyte subsets in IgA nephropathy (IgAN). Some microRNAs have been reported to influence T helper differentiation. Here, we explored the underlying mechanism regarding how miRNAs regulate lymphocyte subsets in IgAN.

Variation in complement factor H affects complement activation in immunoglobulin A vasculitis with nephritis.

Background: Immunoglobulin A (IgA) vasculitis with nephritis (IgAVN) and IgA nephropathy (IgAN) are widely considered as related diseases. Considerable evidences support the notion of involvement of complement activation in both IgAVN and IgAN. Our previous studies identified a genetic variant in complement factor H (CFH), rs6677604, as an IgAN-susceptible variant by genome-wide association study, and further confirmed its linkage to CFHR3-1Δ and proved its influence on complement activation and thereby on IgAN susceptibility.

[Motion-in-depth Perception and Static Stereopsis of Patients with Strabismics].

Objective: To determine the role of motion-in-depth perception and static stereopsis in strabismics, and factors associated with the perception of motion-in-depth.

Methods: A total of 84 strabismic patients (including 57 intermittent exotropes, 12 constant exotropes and 15 esotropes) and 16 normal controls were recruited. Binocular fusion ability, static stereopsis and motion-in-depth perception were tested using the computer-generated stereoscopic stimuli.

Clinical Analysis of 1593 Patients with Infectious Endophthalmitis: A 12-Year Study at a Tertiary Referral Center in Western China.

Background: Infectious endophthalmitis is a severe ocular inflammation which can cause devastating visual loss. The aim of the study was to identify the demographic and clinical features of infectious endophthalmitis in Western China for better prophylaxis and treatment of this disease.

Methods: A.

[Visual performance of amblyopia before and after correcting higher order aberrations with adaptive optics system].

Objective: To investigate visual performance of monocular amblyopia before and after correcting higher order aberrations (HOAs) with adaptive optics system.

Methods: Visual acuity (VA) and contrast sensitivity (CS) thresholds of ten monocular amblyopes were measured before and after correcting higher order aberrations with adaptive optics system. The change of them were analyzed.

Association between lumican gene -1554 T/C polymorphism and high myopia in Asian population: a meta-analysis.

Aim: To investigate the association between lumican gene -1554 T/C polymorphism and high myopia susceptibility.

Methods: We searched the published literature in the Medline, Embase, and CBM databases from inception to July 2013. A meta-analysis was performed by the programs RevMan 5.

Relationship between higher-order aberrations and myopia progression in schoolchildren: a retrospective study.

Aim: To investigate the relationship between higher-order aberration (HOA) and myopic progression in school children.

Methods: Between April 23, 2011 and August 29, 2011 in the children's myopia outpatient clinic of the West China Hospital of Sichuan University, 148 eyes of 74 schoolchildren were reviewed. HOAs for a 6-mm pupil were measured with an aberrometer.