[Effects of caloric restriction on the oxidative stress injury and the expression of SIRT3 in PC12 cell].

Objective: To study the regulation effects of CR (caloric restriction) and SIRT3 in the H2O2-induced oxidative stress injury of PC12 cell.

Methods: The cells were divided into four groups: H2O2, H2O2 + CR, CR and control (high glucose). For control and H2O2 group, cells were cultured in DMEM containing 0.