[Clinical observation of isolated congenital anosmia].

Objective: To introduce 8 patients with isolated congenital anosmia and to discuss the clinical manifestations, imaging characteristics and family characteristics of this rarely seen disorder.

Methods: Eight patients with isolated congenital anosmia treated between April 2007 and April 2012 were reviewed retrospectively. There were 4 males and 4 females.

[Expression of odorant receptor genes on the olfactory epithelium following olfactory nerve disconnection].

Objective: To constitute the animal model of unilateral olfactory nerve transection and observe the expression level and distribution of odorant receptors.

Methods: Thirty-two rats were divided into two groups: the olfactory nerve transection group (20) and the control group (12). The former group received the operation to transect the left olfactory nerve following the left olfactory bulb was exposed under microscope and the latter group did not give any disposal.

[Experience in overlay tympanoplasty].

Objective: To explore the experience and value of overlay tympanoplasty.

Methods: Sixty-three ears with overlay tympanoplasty were reviewed and followed up for the external auditory canal, tympanic membrane and hearing.

Results: The diseases of the patients included middle ear cholesteatoma in 25 ears and chronic suppurative otitis media in 38 ears.

[Effect of Betamethasone on the cAMP of olfactory receptor neurons in rat].

Objective: To observe the effects of Betamethasone on the cyclic adenosine monophosphate (cAMP) in olfactory receptor neurons (ORNs) and explore the possible mechanisms of the recovery of olfactory disorders by steroid treatment

Methods: ORNs membrane was extracted and incubated with 0.1 mg/ml and 1.0 mg/ml Betamethasone.

[Clinical features of primary ciliary dyskinesia].

Objective: To investigate the clinical features, diagnosis and treatment of primary ciliary dyskinesia (PCD).

Methods: Three cases of PCD received endoscopic sinus surgery and were followed up for life quality and recovery. Among these 3 cases, two were twin brothers and the other girl was twin born with a healthy brother.