Publications by authors named "Xu-Peng Yue"
Article Synopsis
- Researchers developed a new multi-kinase inhibitor called CS2164, targeting key pathways involved in tumor growth and angiogenesis.
- CS2164 effectively inhibited several key kinases, resulting in reduced tumor blood vessel formation, cell proliferation, and differentiation of immune cells in tumors.
- In animal studies, CS2164 showed significant tumor growth inhibition and regression at manageable doses, suggesting potential as a promising cancer treatment.
Combination of low doses of histone deacetylases inhibitors and chemotherapy drugs is considered as one of the most promising strategies to increase the anticancer efficacy. Chidamide is a novel benzamide chemical class of HDAC inhibitor that selectively inhibited HDAC1, 2, 3 and 10. We sought to determine whether chidamide may enhance platinum-induced cytotoxicity in NSCLC cells.
View Article and Find Full Text PDF