New triterpenoids from the Cyclocarya paliurus (Batalin) Iljinskaja and their anti-fibrotic activity.

Cyclocarya paliurus, a Chinese herbal medicine and new food resource, contains a triterpenic-acid-rich extract that demonstrated ameliorative effect on diabetic nephropathy (DN). A more in-depth discovery of functional components led to the isolation of seven new triterpenoids including two pentacyclic triterpenes, 1α,2α,3β,23-tetrahydroxyolean-12-en-28-oic acid and 2α,3β,22α-tirhydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranoside, and five tetracyclic triterpenoid glycosides (cypaliurusides N-R), together with twelve known compounds from the leaves of C. paliurus.

Two new triterpenoids from the leaves of (Batalin) Iljinskaja.

Two previously undescribed triterpenoids (), along with thirteen known compounds () were isolated from a CHCl-soluble extract of the leaves of . Their structures were established on the basis of chemical and spectroscopic approaches. These compounds were assessed for their therapeutic effects on diabetic nephropathy (DN)-evoked fibrosis through High-Glucose and transforming growth factor-β1 (TGF-β1) challenged HK-2 cells.

Etiology of Anthracnose in Jiangsu Province, China.

is an extremely valuable and multifunctional tree species whose leaves have traditionally been used in used in medicine or as a medicinal tea in China. In recent years, anthracnose has been frequently observed on young leaves of in several nurseries located in Jiangsu Province, resulting in great yield and quality losses. To date, no information is available about the prevalence of anthracnose in China.

Stem Canker on Is Caused by .

, an important endangered plant in China, has considerable medicinal, timber, and horticultural value. However, little is known about diseases that affect its health. In recent years, stem canker diseases on have been observed frequently in newly established nurseries in Jiangsu Province, China.

Triterpenoids from Cyclocarya paliurus and their inhibitory effect on the secretion of apoliprotein B48 in Caco-2 cells.

Five previously undescribed compounds including two triterpenoid aglycones, 3β,23-dihydroxy-1,12-dioxo-olean-28-oic acid and 3β,23,27-trihydroxy-1-oxo-olean-12-ene-28-oic acid, and three triterpenoid glucosides cyclocarioside L-N, along with 17 known compounds were isolated from a CHCl-soluble extract of the leaves of Cyclocarya paliurus. Two 27-nor-triterpenoid glycosides were isolated from the genus for the first time. Furthermore, the characterized compounds were tested for the inhibitory effects on apoliprotein B48 secretion in Caco-2 cells.

[Phenotypic diversity of natural Cyclocarya paliurus populations seed traits].

With the seeds from nine natural Cyclocarya paliurus populations as test materials, their phenotypic traits, including 1000-seed weight, seed size, seed diameter, seed thickness, and seed diameter/thickness ratio, were investigated, and the phenotypic diversity among and within the populations were studied by the methods of ANOVA analysis, hierarchical cluster analysis, and correlation analysis. Significant differences were observed in the 1000-seed weight, seed size, seed diameter, and seed thickness among and within the populations, and in the seed diameter/thickness ratio within the populations, illustrating that there existed high phenotypic diversity of seed traits at these two levels. The mean phenotypic differentiation coefficient (V) of test seed traits was 20.