Publications by authors named "Xu-Jun Wu"
Neuropeptide S (NPS), an endogenous neuropeptide consisting of 20 amino acids, selectively binds and activates G protein-coupled receptor named neuropeptide S receptor (NPSR) to regulate a variety of physiological functions. NPS/NPSR system has been shown to play a pivotal role in regulating learning and memory in rodents. However, it remains unclear that how NPS/NPSR system affects neuronal functions and synaptic plasticity after learning.
View Article and Find Full Text PDFObjectives: The purpose of this study was to assess whether trans-lymphatic contrast-enhanced ultrasound (CEUS) combined with sentinel lymph node biopsy can be used to assess the status of cervical lymph nodes and skip metastasis in patients with early squamous cell carcinoma (SCC) of the oral tongue.
Methods: This study included 21 subjects with early oral tongue SCC who received multiple intramucosal peritumoral injections of Sonazoid. CEUS examinations were performed immediately after Sonazoid injection to identify sentinel lymph nodes (SLNs).
Article Synopsis
- Drug addicts often experience intense cravings triggered by cues associated with drug use, making it critical to develop methods to reduce these cravings to aid recovery.
- The study explored whether inhibiting the insular cortex or repeated, non-rewarding exposures could diminish morphine-induced conditioned place preference (CPP) in rhesus monkeys, as the insula is linked to addiction.
- Despite efforts to inactivate the insula, the study found no effect on CPP expression, and morphine-related memories persisted over a period of six years, highlighting challenges in extinguishing drug-associated memories and implications for addiction treatment.
[Three-dimensional finite element analysis on the effect of posterior cross-bite of individual teeth on temporomandibular joint].
Zhonghua Kou Qiang Yi Xue Za Zhi
February 2013
Objective: To analyze the stress distribution of temporomandibular joint (TMJ) in posterior cross-bite of individual teeth and in normal occlusion during the intercuspal occlusion (ICO).
Methods: On the basis of the geometric TMJ model of normal occlusion, the TMJ finite element model of posterior cross-bite of individual teeth was reconstructed. The occlusal force and boundary conditions were applied on the model.
Article Synopsis
- Rhesus monkeys can develop a dependence on morphine, as shown in a study.
- The monkeys displayed a strong conditioned place preference (CPP) for areas associated with morphine, which lasted over 36 months.
- This model could help researchers better understand addiction and its effects in humans.