Objective: To explore the influencing factors for the maintenance of valid patents of compound traditional Chinese medicines in treating cardiovascular and cerebrovascular diseases.
Method: Logistic regression analysis was used to detect the influencing factors for the maintenance of valid patents.
Result: The maintenance of valid patents of compound traditional Chinese medicines in treating cardiovascular and cerebrovascular diseases was closely related to many factors, such as their invention, patent rights' transfer, patent claims and patent declaration documents.
Spectrochim Acta A Mol Biomol Spectrosc
February 2012
The interaction between Cr(2)O(7)(2-) and human serum albumin (HSA) was investigated using fluorescence, UV/vis, FT-IR, CD spectroscopy, and molecular modeling method. The experimental results showed that the fluorescence quenching of HSA by Cr(2)O(7)(2-) is a result of the formation of HSA-chromium(VI) complex; static quenching was confirmed to result in the fluorescence quenching. The corresponding thermodynamic parameters showed that the process of binding Cr(2)O(7)(2-) on HSA was a spontaneous molecular interaction procedure.
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