Association of serum uric acid levels with osteoporosis and bone turnover markers in a Chinese population.

Recent evidence shows that uric acid is protective against some neurological diseases, but can be detrimental in many metabolic and cardiovascular disorders. In this study, we examined the association between serum uric acid levels and bone metabolism in Chinese males and postmenopausal females. A total of 943 males and 4256 postmenopausal females were recruited in Shanghai.

Association of bone turnover markers with glucose metabolism in Chinese population.

The association between type 2 diabetes (T2DM) and bone metabolism has been discussed previously but is controversial. In this study we aimed to evaluate the association of bone turnover markers with glucose metabolism in Chinese population, in which 919 males and 4171 postmenopausal females in a region of Shanghai were recruited. Anthropometric and biochemical traits related to glucose and bone metabolism were analyzed.

[Epidemiological characteristics of major abnormal electrocardiogram in adults from Shanghai].

Objective: To understand the prevalence, characteristics and risk factors of major abnormal electrocardiogram (MA-ECG) in adults living in Shanghai.

Methods: The cross-sectional dataset of prevalence survey on diabetes and metabolic syndrome in adults, aged 20-74 years, from Shanghai, in 2007-2008, was analyzed. Demographic information, personal and, family histories of diseases were collected.

Metabolic disorders increase the risk to incident cardiovascular disease in middle-aged and elderly Chinese.

Objective: The association of metabolic syndrome (MetS) with cardiovascular diseases (CVD) has not been adequately explored in middle-aged and elderly Chinese. This study aimed to investigate MetS' prevalence and its impact on the CVD incidence in this specific population group.

Methods: A data set of a community-based prospective cohort study was analyzed.

Liver enzymes concentrations are closely related to prediabetes: findings of the Shanghai Diabetes Study II (SHDS II).

Objective: To investigate the relationship of liver enzymes with hyperglycemia in a large population in Shanghai and identify the association between liver enzymes and insulin resistance.

Methods: A total of 3 756 participants were enrolled. Each participant underwent an oral glucose tolerance test and completed a questionnaire.

Cigarette smoking increases risk for incident metabolic syndrome in Chinese men-Shanghai diabetes study.

Objective: To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.

Methods: A total of 693 men with no MetS at baseline were followed for 2.9-5.

Non-alcoholic fatty liver disease's prevalence and impact on alanine aminotransferase associated with metabolic syndrome in the Chinese.

Background And Aim: Non-alcoholic fatty liver disease (NAFLD) is becoming a major public health hazard in China. The present study aimed to estimate the prevalence of NAFLD, NAFLD with abnormal serum alanine aminotransferase (ALT) levels, and determine the potential associations of ALT levels with the components of metabolic syndrome (MetS) in the absence or presence of NAFLD in Chinese adults.

Methods: A population-based cross-sectional survey was conducted with 2226 participants.

Comparison of body mass index with body fat percentage in the evaluation of obesity in Chinese.

Objective: To evaluate the present Chinese body mass index (BMI) criteria with body fat percentage (BF%) in determining obesity in Chinese population.

Methods: A total of 4 907 subjects (age: 20-90 yrs) were enrolled in the baseline survey of a longitudinal epidemiological study, and 2 638 of them were reevaluated in 5.5 years later.

Relationship of plasma creatinine and lactic acid in type 2 diabetic patients without renal dysfunction.

Background: As one of most widely-used biguanides, metformin can induce the lactic acidosis in patients with renal failure though its incidence is very low. However, lactic acidemia induced by metformin was reported in patients without renal dysfunction. It is unclear that whether lactatemia exists in diabetic patients with normal renal function in Chinese or not and its influencing factors.

Serum vaspin level in relation to postprandial plasma glucose concentration in subjects with diabetes.

Background: Vaspin is a newly-identified adipocytokine related to obesity and insulin sensitivity. However, its pathophysiologic role in humans remains largely unknown. The aim of our study was to investigate the relationship between serum vaspin level and glucose metabolism or obesity in Chinese adults.

[Prevalence of and risk factors associated with diabetic retinopathy in pre-diabetic and diabetic population in Shanghai community].

Objective: To determine the prevalence and risk factors of diabetic retinopathy (DR) in the Diabetes Mellitus (DM) and impaired glucose regulation (IGR) population in Shanghai Community.

Methods: DR screening after the epidemiologic study of metabolic syndrome in Huayang and Caoyang Community, Shanghai was conducted among 1300 patients with DM or IGR during June 2005 and March 2006, Digital non-mydriatic fundus photography was performed for each eye in all subjects. Other factors, including diabetes related history, BMI, WHR, fasting plasma glucose, HbA1c, serum lipid and blood pressure were also assessed.

[Orthogonal factor analysis on metabolic syndrome].

To elucidate the principal of orthogonal factor analysis, using an example of factor analysis of metabolic syndrome. The basic structures and the fundamental concepts of orthogonal factor analysis were introduced and data involving 1877 women aged of 35-65 years, selected from a cross-sectional study, which was conducted in 1998 - 2001 in Shanghai, were included in this study. Factor analysis was carried out using principle components analysis with Varimax orthogonal rotation of the components of the metabolic syndrome.

[Serum lipid profile changes of the adults in Shanghai communities].

Objective: To explore the adult lipid profile of Huayang community from 1998 to 2000 and Caoyang communities in 2001.

Methods: Representative serum samples of 5628 adults (aged 20 - 95 years) were obtained in Huayang and Caoyang communities during 1998.9 and 2001.

[Application of Excel Visual Basic for efficiently complete statistic analysis].

Objective: In order to analyze multiple statistic tables more efficiently Excel Visual Basic for Application (VBA) was introduced through the use of an example of calculating standardized mortality rates (SMRs).

Methods: Mortality data of cancer and cardiovascular diseases, by sex and age, have been collected from 1991 to 2003 by the Center for Disease Control and Prevention of Shanghai Huangpu District. Standard population composition was defined as Chinese census statistics in 2000.

[A case control study on the risk factors of proteinuria in patients with type 2 diabetes].

Objective: To assess factors predisposing to proteinuria in patients with type 2 diabetes mellitus (DM).

Methods: A case-control study was conducted on two groups of patients with type 2 diabetes without proteinuria (urine protein < 300 mg/24 h, n = 106) and with proteinuria (urine protein >or= 500 mg/24 h, n = 106). The two groups were matched by age (+/- 3 years), sex, race and place of residence.