Differential expression of Bmp2, Bmp4 and Bmp3 in embryonic development of mouse anterior and posterior palate.

Background: The palate is differently regulated and developed along the anterior-posterior axis. The Bmp signal pathway plays a crucial role in palatogenesis. Conditioned-inactivation of Bmp type I receptor Alk2 or Alk3 in the neural crest or craniofacial region leads to palatal cleft in mice.