[Clinicopathologic analysis of vulnerable plaque in autopsy with acute coronary syndrome].

Objective: To observe pathohistological features of vulnerable plaques in coronary arteries.

Methods: Autopsy coronary samples from 67 patients died of acute coronary syndrome (ACS) and 60 patients of non-cardiac death from 1992 to 2006 in Beijing Hospital were examined. Morphological features of vulnerable plaques of ACS cases were evaluated in terms of thrombus, ratio of lipid core, the minimal thickness of fibrous cap and the density of inflammatory infiltration.

[Expression of cytokine IL-1α and S100β in different types of plaques in Alzheimer's disease].

Objective: To study the significance of cytokine IL-1α and S100β expression in formation and evolution of different types of plaques in Alzheimer's disease.

Methods: Thirty-four autopsy cases of Alzheimer's disease encountered during the period from 1982 to 2008 were retrieved from the archival files of Department of Pathology, Beijing Hospital. Tissue blocks were taken from hippocampus for dual immunostaining for IL-1α/Aβ and S100β/Aβ.

[Pathologic study of diabetic cardiomyopathy].

Objective: To study the histopathologic features, differential diagnosis and pathogenesis of diabetic cardiomyopathy.

Methods: The clinicopathologic features of 40 autopsy cases of diabetes mellitus were studied. The hearts from another 40 cases of non-diabetic elderly deceased were used for comparison.