Deptor protects against myocardial ischemia-reperfusion injury by regulating the mTOR signaling and autophagy.

Deptor knockout mice were constructed by crossing Deptor Floxp3 mice with myh6 Cre mice, establishing a myocardial ischemia-reperfusion (I/R) model. Deptor knockout mice exhibited significantly increased myocardial infarction size and increased myocardial apoptosis in vivo. ELISA analysis indicated that the expression of CK-MB, LDH, and CtnT/I was significantly higher in the Deptor knockout mice.

Treatment and prediction of wastewater from waste transfer station in the eastern rural area of China by a combined system of anaerobic-oxic-anoxic-oxic, coagulation and adsorption.

In this study, a combined system of anaerobic-oxic-anoxic-oxic, coagulation and adsorption (AOAOCA) was used to treat the real waste transfer station (WTS) wastewater. The effects of hydraulic retention time (HRT), sludge reflux ratio (SRR), mixed liquid reflux ratio (MLRR), coagulant and zeolite on the contaminants removal efficiency were investigated. When the AOAOCA system was operated at the optimal conditions (HRT of 8 d, SRR of 70%, MLRR of 200%, PAFC as coagulant with dosage of 750 ppm and 1-3 mm zeolite with filling rate of 60%), the effluent COD, NH-N and TP could reach 82.

Aberrant amplitude of low-frequency fluctuation and functional connectivity in children with different subtypes of ADHD: a resting-state fNIRS study.

Background: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with different subtypes of pathogenesis. Insufficient research on the subtypes of ADHD has limited the effectiveness of therapeutic methods.

Methods: This study used resting-state functional near-infrared spectroscopy (fNIRS) to record hemodynamic signals in 34 children with ADHD-combined subtype (ADHD-C), 52 children with ADHD-inattentive subtype (ADHD-I), and 24 healthy controls (HCs).

Study on the discoloration phenomenon caused by iron ion oxidation in Boston ivy pads and its effect on adhesion force.

Boston ivy has received much attention from researchers owing to its exceptional climbing abilities. However, many aspects of their adhesion behavior remain unresolved. Our research has discovered a phenomenon of oxidation and discoloration in Boston ivy pads, which leads to a significant decrease in adhesion force.

Efficient Nitrate Formation in Fog Events Implicates Fog Interstitial Aerosols as Significant Drivers of Atmospheric Chemistry.

Clouds and fogs, consisting of tiny water droplets formed by the condensation of water in supersaturated air, are vital in atmospheric chemistry, as they facilitate multiphase reactions. While measuring high-altitude cloud is challenging, fog as ground-level clouds offer a unique opportunity for direct observation. In this study, we explored radiation fogs in the North China Plain using an advanced aerosol-fog sampling system to measure the chemical and physical properties of both inactivated interstitial aerosols and activated fog droplet residues.

Vibration Position Detection of Robot Arm Based on Feature Extraction of 3D Lidar.

In the process of construction, pouring and vibrating concrete on existing reinforced structures is a necessary process. This paper presents an automatic vibration position detecting method based on the feature extraction of 3D lidar point clouds. Compared with the image-based method, this method has better anti-interference performance to light with reduced computational consumption.

Thrombotic Thrombocytopenia Purpura (TTP) following emergent aortic valve replacement after a complicated TAVR procedure: a case report and review of the literature.

Background: Thrombotic thrombocytopenic purpura (TTP) is a rare hematological disorder. The occurrence of TTP subsequent to an emergent aortic valve replacement after a TAVR procedure is exceedingly uncommon with only a few reported cases worldwide.

Case Presentation: We report the case of a 70-year-old female patient diagnosed with aortic insufficiency.

The 500-meter long-term winter wheat grain protein content dataset for China from multi-source data.

In China, the exigency for precise wheat grain protein content (GPC) data rises with growing food consumption demands and global market competition. However, due to the lack of extensive, prolonged high-resolution benchmark data, previous GPC studies have primarily focused on experimental fields, small geographic units, and limited temporal scopes. Additionally, the diverse geographical terrain in China exacerbates the challenges of large-scale GPC estimation.

The Impact of Agroecosystems on Nitrous Acid (HONO) Emissions during Spring and Autumn in the North China Plain.

Solar radiation triggers atmospheric nitrous acid (HONO) photolysis, producing OH radicals, thereby accelerating photochemical reactions, leading to severe secondary pollution formation. Missing daytime sources were detected in the extensive HONO budget studies carried out in the past. In the rural North China Plain, some studies attributed those to soil emissions and more recent studies to dew evaporation.

CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses.

Coronaviruses have threatened humans repeatedly, especially COVID-19 caused by SARS-CoV-2, which has posed a substantial threat to global public health. SARS-CoV-2 continuously evolves through random mutation, resulting in a significant decrease in the efficacy of existing vaccines and neutralizing antibody drugs. It is critical to assess immune escape caused by viral mutations and develop broad-spectrum vaccines and neutralizing antibodies targeting conserved epitopes.

Quantitative analysis of microplastics in water environments based on Raman spectroscopy and convolutional neural network.

With the increasing interest in microplastics (MPs) pollutants, quantitative analysis of MPs in water environment is an important issue. Vibrational spectroscopy, represented by Raman spectroscopy, is widely used in MP detection because they can provide unique fingerprint characteristics of chemical components of MPs, but it is difficult to provide quantitative information. In this paper, an ingenious method for quantitative analysis of MPs in water environment by combining Raman spectroscopy and convolutional neural network (CNN) is proposed.

Long-term variations in surface ozone at the Longfengshan Regional Atmosphere Background Station in Northeast China and related influencing factors.

Surface ozone (O) is a crucial air pollutant that affects air quality, human health, agricultural production, and climate change. Studies on long-term O variations and their influencing factors are essential for understanding O pollution and its impact. Here, we conducted an analysis of long-term variations in O during 2006-2022 at the Longfengshan Regional Atmosphere Background Station (LFS; 44.

ROS mediated by TrPLD3 of Trichothecium roseum participated cell membrane integrity of apple fruit by influencing phosphatidic acid metabolism.

Trichothecium roseum is a typical necrotrophic fungal pathogen that not only bring about postharvest disease, but contribute to trichothecenes contamination in fruit and vegetables. Phospholipase D (PLD), as an important membrane lipid degrading enzyme, can produce phosphatidic acid (PA) by hydrolyzing phosphatidylcholine (PC) and phosphatidylinositol (PI). PA can promote the production of reactive oxygen species (ROS) by activating the activity of NADPH oxidase (NOX), thereby increasing the pathogenicity to fruit.

Anticoagulant therapy in orthopedic surgery - a review on anticoagulant agents, risk factors, monitoring, and current challenges.

Orthopedic surgeries are associated with high-risk of thromboembolism which occurs in 40% to 60% of orthopedic patients in the absence of thromboprophylaxis. Conventionally heparin anticoagulants were used for thromboprophylaxis and currently direct oral anticoagulants (DOACs) are widely used due to their minimal complexity. Anticoagulant use carries bleeding risk and requires optimal laboratory monitoring through conventional thrombin-based assays, anti-Xa assay, anti-IIa assay and contemporary ecarin chromogenic assay (ECA) and rotational thromboelastometry.

Henna plant biomass enhanced azo dye removal: Operating performance, microbial community and machine learning modeling.

The bio-reduction of azo dyes is significantly dependent on the availability of electron donors and external redox mediators. In this study, the natural henna plant biomass was supplemented to promote the biological reduction of an azo dye of Acid Orange 7 (AO7). Besides, the machine learning (ML) approach was applied to decipher the intricate process of henna-assisted azo dye removal.

-mediated melanin synthesis is essential to growth and development, stress adaption, and pathogenicity in .

Scytalone dehydratase (brm1) is one of the key enzymes in 1, 8-dihydroxynaphthalene (DHN) melanin synthesis, which mediates melanin biosythesis and regulates cell biological process of plant fungi, but its function in , the causal agent of pear black spot, is unclear. Brm1 in was cloned, identified, and named as . An -deletion mutant was generated and revealed that the deletion of leads to a significant decrease in melanin production and forms orange colony smooth spores.

Tunable Periodic Nanopillar Array for MAPbI Perovskite Photodetectors with Improved Light Absorption.

In the field of optoelectronic applications, the vigorous development of organic-inorganic hybrid perovskite materials, such as methylammonium lead triiodide (MAPbI), has spurred continuous research on methods to enhance the photodetection performance. Periodic nanoarrays can effectively improve the light absorption of perovskite thin films. However, there are still challenges in fabricating tunable periodic patterned and large-area perovskite nanoarrays.

Hollow-conical atomic beam from a low-velocity intense source.

We demonstrate, for the first time, a hollow-conical atomic beam from a standard low-velocity intense source. Experimental results and numerical simulations indicate that the hollow-conical feature is caused by the converging-diverging extraction process. The degree of hollowness can be reduced by using a weaker push beam and extending the length of transverse cooling.

Severe photochemical pollution formation associated with strong HONO emissions from dew and guttation evaporation.

The unknown daytime source of HONO has been extensively investigated due to unexplained atmospheric oxidation capacity and current modelling bias, especially during cold seasons. In this study, abrupt morning increases in atmospheric HONO at a rural site in the North China Plain (NCP) were observed almost on daily basis, which were closely linked to simultaneous rises in atmospheric water vapor content and NH concentrations. Dew and guttation water formation was frequently observed on wheat leaves, from which water samples were taken and chemically analyzed for the first time.