Organic trace elements enhance growth performance, antioxidant capacity, and gut microbiota in finishing pigs.

Excessive inorganic trace elements are added to livestock and poultry feed to meet the needs of animals, accompanied by frequent occurrence of excretion and gastrointestinal stress. Replacing inorganic trace elements with organic trace elements provides a promising solution to alleviate these problems. Therefore, this study aimed to assess the impact of replacing all inorganic trace elements (ITMs) in feed on the growth performance, meat quality, serum parameters, trace element metabolism, and gut microbiota of finishing pigs.

Comprehensive metabolic profiling of three plants of Ardisia based on UPLC-QTOF-MS coupled with bioactivity assays.

Ethnopharmacological Relevance: Ardisia is a large genus of Primulaceae, 734 accepted species worldwide, and most species are used as ethnomedicines for the treatment of bruises, rheumatism, tuberculosis, and various inflammatory diseases. According to our previous ethnobotanical survey, Ardisia gigantifolia Stapf, Ardisia hanceana Mez (Da-luo-san), and Ardisia crenata Sims (Xiao-luo-san) are commonly used in folk medicine for the treatment of rheumatism. Among them, A.

Chiral Membrane Containing Subnanometer Channels for Enantioselective Transport Amino Acids.

The research of chiral separation technology is of great significance for understanding the origin of life and promoting the application of chiral molecules. Herein, anionic chiral pillar[6]arene and cationic pillar[6]arene were designed and synthesized, and a chiral pillar[6]arene membrane was constructed by layer-by-layer assembly through electrostatic interactions. The transport rates of l and d in this channel were 14.

Enantioselective Carbonylative Cyclization of Alkenes with C-H Bonds for Synthesis of γ-Lactams Bearing an α-Quaternary Carbon.

The development of effective synthetic methods to construct γ-lactams bearing a chiral α-quaternary carbon from relatively inert C(O)-H bonds with alkenes has been an elusive challenge. Herein, we used a naphthylamine-derived phosphine oxide ligating Ni and Al bimetallic catalyst to realize a carbonylative cyclization of formyl C-H bonds with alkenes, highly regio- and enantioselectively constructing γ-lactams bearing a chiral α-quaternary carbon in up to 99% yield and 98% ee. These γ-lactams proved to be versatile synthetic precursors for many biologically active molecules.

Elevated serum miR-142-5p correlates with ischemic lesions and both NSE and S100β in ischemic stroke patients.

Background: This study aims to evaluate the correlation between miRNAs and known nerve injury markers neuron-specific enolase (NSE) and S100β in ischemic stroke (IS) patients, exploring its efficacy.

Methods: We retrospectively analyzed 86 IS patients and 32 healthy controls. Clinical and neurological examinations were performed in the admitted patients and the severity of neurological deficits was assessed by National Institutes of Health Stroke Scale (NIHSS).

New insights into the charge property at active sites boost PMS activation over LaFeMnO.

Perovskite-based materials have become a new direction for peroxymonosulfate (PMS) activation in pollutants degradation. However, the mechanism towards PMS activation remains insufficient. In this paper, a series of LaMMnO materials with B-site doping were developed by sol-gel self-propagating combustion method.

Development of an Angular Stiffness Sensor to Measure Dental Implant Stability In Vitro.

This investigation aims to develop an angular stiffness sensor intended for measuring dental implant stability in bone. The sensor hardware included a tiny eccentric motor and an accelerometer to measure a flex constant of an implant with its abutment. The sensor software included a mechanics-based model to convert the flex constant to angular stiffness at the implant/abutment junction to indicate the stability.

Sarcopenia and frailty among older Chinese adults: Findings from the CHARLS study.

Background: Sarcopenia and frailty are common among elderly individuals and present substantial health hazards. Exploring their relationship is essential for optimizing geriatric healthcare, particularly within the context of China.

Methods: A population-based cross-sectional design was employed using data from the China Health and Retirement Longitudinal Study (CHARLS).

Vision-Related Quality of Life After Fyodorov-Zuev Keratoprosthesis in China.

Purpose: The purpose of this study was to assess vision-related quality of life (VR-QoL) and its determinants in patients with implanted Fyodorov-Zuev (MICOF) KPro.

Methods: Eighty-eight patients with bilateral corneal blindness who underwent unilateral Fyodorov-Zuev (MICOF) KPro implantation were included in this cross-sectional study. VR-QoL was assessed using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25).

Controlled Release of La Ions for Enhanced Wheat Seed Germination Based on Phosphate Pillar[5]arene Nanogating.

Rare earth elements (REEs), vital and limited resources, also play a significant role in agriculture. Previous findings indicated that the proper concentration of REEs could enhance the germination process, seed germination rate, and seedling growth and development. This paper introduces designing, synthesizing, and assembling a new type of tapered nanogates for separating and detecting lanthanide ions (La).

Elevated circulating HHIP levels in patients with metabolic syndrome.

Abnormal fat accumulation can lead to metabolic syndrome (MetS), increasing the risk of diabetes and cardiovascular disease in MetS patients. Early identification of MetS risk is essential for effective disease prevention. Using bioinformatics methods, we sought biomarkers for MetS.

Tricetin attenuates atherosclerosis by suppressing macrophage ferroptosis via activation of the NRF2 pathway.

Tricetin (TRI) has been reported to have anti-inflammatory and antioxidant effects; however, its therapeutic potential and molecular mechanisms in atherosclerosis remain unclear. In this study, we aimed to investigate the effects of TRI on atherosclerosis. Our findings revealed that TRI inhibits macrophage ferroptosis by activating the NRF2 pathway.

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis.

Primary dysmenorrhea (PDM) refers to the occurrence of spasmodic colicky pain in the lower abdomen without any obvious pelvic pathology, often accompanied by other systemic symptoms, which significantly reduces the quality of life of women with PDM, 45%-95% of menstrual women are affected by it. Despite the high incidence of PDM, it is often not well treated and is ignored by relevant researchers and women themselves. Herbs-partitioned moxibustion (HPM) is a characteristic external therapy in traditional Chinese medicine (TCM), which is widely used to treat diseases in China; it treats diseases by applying a Chinese herbal formula on the patient's acupoints and then igniting moxa sticks on the herbal formula for moxibustion therapy.

The relationship between visual health and influencing factors among primary and secondary school students: a survey based in the Ningxia Hui Autonomous Region of China.

Introduction: The myopia rate of young people around the world, especially in China, has continued to rise, and the vision health of primary and secondary school students has gradually become a global concern. It was to explore the current characteristics of vision status and their intrinsic links to influencing factors of the Ningxia Hui Autonomous Region primary and secondary school students under regional characteristics.

Methods: 1,670 primary and secondary school students in Ningxia Hui Autonomous Region were surveyed using Vision examination, International Physical Activity Scale, Lifestyle Behavior Scale.

Elevated circulating regenerating islet-derived protein 4 levels in patients with metabolic syndrome and related to its key components.

Purpose: Regenerating islet-derived protein 4 (REG4) is a secretory protein that belongs to the C-type lectin superfamily. This study aims to explore the diagnostic value of REG4 as a potential biomarker for metabolic syndrome by analyzing the correlation between serum REG4 levels and metabolic syndrome.

Methods: Serum REG4 levels were measured using enzyme-linked immunosorbent assay (ELISA).

Study of the synergistic effect of analogical and explicit learning in beginning junior tennis players.

Motor skill learning is a field where implicit and explicit synergistic learning is particularly evident in authentic situations. While current research on analogical learning, an effective method of implicit learning, is largely focused on theoretical discussions and separability studies, there are relatively few studies that combine analogical learning with explicit learning. In this study, a one-way experimental design was utilized to investigate the synergistic effect of analogical learning and explicit learning on the acquisition of forehand hitting skills in beginning tennis players.

Enantioselective Construction of Oxindoles Bearing a Quaternary Carbon via Ni-Al Bimetal-Catalyzed Formyl C-H Alkylation.

Enantioselective transition metal-catalyzed C-H alkylation emerges as one of the most atom- and step-economical routes to chiral quaternary carbons, while big challenges still remain with acyl C-H alkylations. Herein, we use a Ni-Al bimetallic catalyst to facilitate a highly regioselective and highly enantioselective C-H alkylation of formamides with alkenes, constructing various oxindoles bearing a chiral quaternary carbon in up to 94 % yield and up to 95 % ee.

Development and characterization of tilapia skin collagen-inulin oleogel as the potential fat substitute in beef patty formulations.

The effects of inulin addition, olive oil content, and ultrasonic treatment on the rheological, texture, and structural properties of collagen-based oleogels were investigated in this study. Furthermore, the fat substitution ability of the oleogel in low-fat beef patties was evaluated. Initially, a uniform and dense network cross-linked structure was found when the ratio of collagen to inulin complex was 1:5.

Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptor phosphorylation pathway.

Inhibition of the ceramide synthetic pathway with myriocin or an antisense oligonucleotide (ASO) targeting dihydroceramide desaturase (DES1) both improved hepatic insulin sensitivity in rats fed either a saturated or unsaturated fat diet and was associated with reductions in both hepatic ceramide and plasma membrane (PM)-sn-1,2-diacylglycerol (DAG) content. The insulin sensitizing effects of myriocin and Des1 ASO were abrogated by acute treatment with an ASO against DGAT2, which increased hepatic PM-sn-1,2-DAG but not hepatic C16 ceramide content. Increased PM-sn-1,2-DAG content was associated with protein kinase C (PKC)ε activation, increased insulin receptor (INSR) phosphorylation leading to reduced insulin-stimulated INSR/Akt phosphorylation, and impaired insulin-mediated suppression of endogenous glucose production.

[Effect of fluid resuscitation with crystalloid combined with plasma on the prognosis of septic patients with hypoalbuminemia].

Objective: To evaluate the difference in efficacy of two fluid resuscitation regimens, crystalloid alone versus crystalloid combined with plasma infusion, on the prognosis of septic patients with hypoalbuminemia.

Methods: A retrospective study was conducted. Septic patients with hypoalbuminemia admitted to the department of critical care medicine of Dongtai People's Hospital from January 2017 to December 2022 were selected as study subjects.

Factors influencing mortality in intracranial infections caused by carbapenem-resistant Klebsiella Pneumoniae.

It remains that intracranial infection has an alarming mortality and morbidity. Klebsiella pneumoniae (KP) have increasingly been isolated in ventriculitis and meningitis episodes. Intracranial infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) account for high mortality.