Clinical characteristics and risk factors of severe pneumonia caused by human bocavirus in children.

Background: The aim of this study was to investigate the clinical characteristics of severe pneumonia caused by human bocavirus (HBoV) infection to explore the associated risk factors.

Methods: We conducted a retrospective review of data from children hospitalized with HBoV pneumonia. Based on the severity of pneumonia, patients were categorized into severe pneumonia and non-severe pneumonia groups.

Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.

Background: Ankylosing spondylitis (AS) is an autoimmune disease characterized by dysfunction of the immune system, which leads to chronic inflammation and progressive ossification of spinal ligaments. The precise pathogenesis of this condition remains unclear, thereby impeding the development of effective treatments.

Methods: We analyzed the GSE25101 dataset and identified the aberrant expression and potential pathogenic role of TXN.

Effect of comprehensive intervention model based on drug-psychology-society-skills on medication compliance and cognitive ability of chronic schizophrenia patients.

Background: The intervention value of a drug-psycho-social-skill model on medication compliance and cognitive ability in patients with chronic schizophrenia was unknown.

Aim: To explore the intervention value of a drug-psycho-social-skill model on medication compliance and cognitive ability in patients with chronic schizophrenia.

Methods: Overall, 98 out-patients and in-patients with chronic schizophrenia treated in our hospital from February 2022 to January 2023 were included and randomly divided into the study (50 patients) and control groups (48 patients).

Dynamic Modulation of Afterglow Emission in Polymeric Phosphors via Inverse Opal Photonic Structures.

Tuning the afterglow of polymeric phosphors is critical for advancing their use in optical data storage and display technologies. Despite advancements in polymer matrix design and dopant engineering, achieving dynamic control over afterglow intensity remains a significant challenge. In this study, a novel approach is introduced for dynamically tuning the afterglow of polymeric phosphors by integrating them into an inverse opal photonic structure.

Innovative development of territories based on the integrated use of social, resource and environmental potential.

This article investigates the interrelationships and interdependencies inherent in the integrated use of the territory's social, resource, and environmental potential to achieve its sustainable development. The basic hypotheses formulated during this study were as follows: Sustainable development of the territory's resource and ecological potential cannot be achieved if its social potential is reduced; Sustainable development of the territory's ecological and social potential can be achieved only if it is economically feasible, that is if it contributes to the sustainable development of the territory's resource potential; Sustainable development of the territory's resource and social potential cannot be achieved while its ecological potential deteriorates; Ensured sustainable development of territories in today's world is only possible with simultaneous integrated use of the territory's social, resource, and environmental potential. The aim of this research is to investigate the interrelationships among these three components and to determine their impact on the overall development of the regions.

DKK3 as a diagnostic marker and potential therapeutic target for sarcopenia in chronic obstructive pulmonary disease.

Sarcopenia, characterized by the progressive loss of muscle mass and function, significantly affects patients with chronic obstructive pulmonary disease (COPD) and worsens their morbidity and mortality. The pathogenesis of muscle atrophy in patients with COPD involves complex mechanisms, including protein imbalance and mitochondrial dysfunction, which have been identified in the muscle tissues of patients with COPD. DKK3 (Dickkopf-3) is a secreted glycoprotein involved in the process of myogenesis.

The malic acid inhibiting inflammation in ankylosing spondylitis by interfering M1 macrophage polarization.

Ankylosing spondylitis (AS) is a motor system immune disease with significant genetic characteristics, resulting in joint fusion, deformity, rigidity, seriously affecting the quality of life of patients. Inflammatory bowel disease (IBD), characterized by intestinal mucosal damage and inflammatory changes, the most common extra-articular manifestation of AS. Due to the limitations of the application of therapeutic drugs, it is urgent to look for new mechanisms and strategies to effectively inhibit AS inflammation is.

Transition-metal-free photochemical reductive denitration of nitroarenes.

We have developed a simple and mild photochemical process for the reductive denitration of nitroarenes under transition-metal-free conditions. This method is compatible with a broad range of functional groups, providing a practical and efficient approach for converting nitroarenes into denitrated arenes. The utility of this protocol is demonstrated through the prompt synthesis of dibenzoxepane.

Machine Learning-Guided Discovery of Copper(I)-Iodide Cluster Scintillators for Efficient X-ray Luminescence Imaging.

Developing efficient scintillators with environmentally friendly compositions, adaptable band gaps, and robust chemical stability is crucial for modern X-ray radiography. While copper(I)-iodide cluster crystals show promise, the vast design space of inorganic cores and organic ligands poses challenges for conventional approaches. In this study, we present machine learning-guided discovery of copper(I)-iodide cluster scintillators for efficient X-ray luminescence imaging.

Coherent growth of high-Miller-index facets enhances perovskite solar cells.

Obtaining micron-thick perovskite films of high quality is key to realizing efficient and stable positive (p)-intrinsic (i)-negative (n) perovskite solar cells, but it remains a challenge. Here we report an effective method for producing high-quality, micron-thick formamidinium-based perovskite films by forming coherent grain boundaries, in which high-Miller-index-oriented grains grow on the low-Miller-index-oriented grains in a stabilized atmosphere. The resulting micron-thick perovskite films, with enhanced grain boundaries and grains, showed stable material properties and outstanding optoelectronic performances.

Sini San ameliorates lipid metabolism in hyperprolactinemia rat with liver-depression.

Sini San (SNS) is used to treat liver depression and is applied in both food and herbal medicine. Hyperprolactinemia (HPRL) is a common endocrine disorder, and patients with HPRL are usually associated with depressive symptoms. However, whether SNS is effective in treating HPRL combined with liver depression and its underlying mechanisms are unknown.

Matrix-induced defects and molecular doping in the afterglow of SiO microparticles.

A deep understanding of how the host matrix influences the afterglow properties of molecule dopants is crucial for designing advanced afterglow materials. Despite its appeal, the impact of defects on the afterglow performance in molecule-doped SiO matrices has remained largely unexplored. Herein, we detail the synthesis of monodisperse SiO microparticles by hydrothermally doping molecules, such as 4-phenylpyridine, 4,4'-bipyridine, and 1,4-bis(pyrid-4-yl)benzene.

Monolithic Integration of Full-Color Microdisplay Screen with Sub-5 µm Quantum-Dot Pixels.

Monolithic integration of color-conversion materials onto blue-backlight micro-light-emitting-diodes (micro-LEDs) has emerged as a promising strategy for achieving full-color microdisplay devices. However, this approach still encounters challenges such as the blue-backlight leakage and the poor fabrication yield rate due to unsatisfied quantum dot (QD) material and fabrication process. Here, the monolithic integration of 0.

Opal-Inspired SiO-Mediated Carbon Dot Doping Enables the Synthesis of Monodisperse Multifunctional Afterglow Nanocomposites for Advanced Information Encryption.

Despite recent advancements in inorganic and organic phosphors, creating monodisperse afterglow nanocomposites (NCs) remains challenging due to the complexities of wet chemistry synthesis. Inspired by nanoinclusions in opal, we introduce a novel SiO-mediated carbon dot (CD) doping method for fabricating monodisperse, multifunctional afterglow NCs. This method involves growing a SiO shell matrix on monodisperse nanoparticles (NPs) and doping CDs into the SiO shell under hydrothermal conditions.

Predictive and therapeutic value of lipoprotein-associated phospholipaseA2 in sarcopenia in chronic obstructive pulmonary disease.

Background: Sarcopenia, characterized by progressive muscle dysfunction, is a common complication of chronic obstructive pulmonary disease (COPD). Our previous study revealed serum Lipoprotein-associated phospholipaseA2 (Lp-PLA2) level significantly increased in COPD and associated with exercise tolerance. This study further investigated the functions and target potential of Lp-PLA2 for sarcopenia in COPD.

Comprehensive investigation in oncogenic functions and immunological roles of NCBP2 and its validation in prostate cancer.

Background: Nuclear cap-binding protein 2 (NCBP2), as the component of the cap-binding complex, participates in a number of biological processes, including pre-mRNA splicing, transcript export, translation regulation and other gene expression steps. However, the role of NCBP2 on the tumor cells and immune microenvironment remains unclear. To systematically analyze and validate functions of NCBP2, we performed a pan-cancer analysis using multiple approaches.

Array-optimized artificial olfactory sensor enabling cost-effective and non-destructive detection of mycotoxin-contaminated maize.

The MobileNetV3-based improved sine-cosine algorithm (ISCA-MobileNetV3) was combined with an artificial olfactory sensor (AOS) to address the redundancy in olfactory arrays, thereby achieving low-cost and high-precision detection of mycotoxin-contaminated maize. Specifically, volatile organic compounds of maize interacted with unoptimized AOS containing eight porphyrins and eight dye-attached nanocomposites to obtain the scent fingerprints for constructing the initial data set. The optimal decision model was MobileNetV3, with more than 98.

Optically compatible infrared camouflage performance of ITO ink.

With the rapid development of military reconnaissance technology, reconnaissance devices have been equipped with wideband reconnaissance ability, which imposes increased requirements on camouflage. Developing multiband camouflage materials with good compatibility has become increasingly important. Indium tin oxide (ITO), a transparent conductive oxide with good comprehensive photoelectric properties, exhibits different absorption, reflectivity, and transmission characteristics in different bands of electromagnetic waves.