Background: Infections with Plasmodium ovale are widely distributed but rarely investigated, and the resulting burden of disease has been underestimated. Plasmodium ovale curtisi Duffy binding protein domain region II (PocDBP-RII) is an essential ligand for reticulocyte recognition and host cell invasion by P. ovale curtisi.
View Article and Find Full Text PDFBackground: Malaria is a worldwide infectious disease. For countries that have achieved malaria elimination, the prevention of re-establishment due to infections in returned travellers has become important. The accurate and timely diagnosis of malaria is the key in preventing re-establishment, and malaria rapid diagnostic tests (RDTs) are frequently used due to their convenience.
View Article and Find Full Text PDFSignificant amounts of fresh and fresh-cut fruits and vegetables are wasted every year due to enzymatic browning. Polyphenol oxidase (PPO) is the key enzyme involved in the enzymatic browning. In the past decades, various methods have been developed to inhibit browning of various fresh produce items.
View Article and Find Full Text PDFPlasmodium ovale curtisi and P. ovale wallikeri are both endemic in sub-Saharan Africa, the Middle East and Southeast Asia. Molecular surveillance data for drug resistance in P.
View Article and Find Full Text PDFThe flavonoid tilianin is derived from the leaves of L. amiales and has been proven to serve a neuroprotective role in cerebral ischemia. Therefore, the aim of the present study was to determine whether tilianin could prevent oxidative stress and the apoptosis of dopaminergic neurons in Parkinson's disease (PD).
View Article and Find Full Text PDFMitochondrial DNA B Resour
March 2022
(Xu and Feng 1975) is the major vector of malaria in Eastern and Southern China. The species is considered a synonym of (Baisas & Hu, 1936), although they differ in several key biological characteristics. Here, we report the complete mitochondrial genome of for the first time.
View Article and Find Full Text PDFsurface-related antigen (SRA) is located on the surfaces of gametocyte and merozoite and has the structural and functional characteristics of potential targets for multistage vaccine development. However, little information is available regarding the genetic polymorphism of . To determine the extent of genetic variation about by characterizing the sequence, 74 samples were collected from migrant workers who returned to China from 12 countries of Africa between 2015 and 2019.
View Article and Find Full Text PDFBiochem Biophys Res Commun
December 2020
Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer. In this study, we aimed to explore the role and mechanism of lncRNA ST8SIA6-AS1 in HCC. We found that ST8SIA6-AS1 was upregulated in HCC tissues and associated with poorer overall survival of HCC patients from TCGA.
View Article and Find Full Text PDFBackground: Current methods to classify local and imported malaria infections depend primarily on patient travel history, which can have limited accuracy. Genotyping has been investigated as a complementary approach to track the spread of malaria and identify the origin of imported infections.
Methods: An extended panel of 26 microsatellites (16 new microsatellites) for Plasmodium falciparum was evaluated in 602 imported infections from 26 sub-Saharan African countries to the Jiangsu Province of People's Republic of China.
Background: Since the National Malaria Elimination Action Plan was launched in China in 2010, local malaria transmission has decreased rapidly. Zero indigenous cases were reported since 2017. However, after 2010, the proportion of imported cases in China increased from 45.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
April 2019
Objective: To understand the malaria epidemic situation and characteristics in Jiangsu Province in 2017, so as to provide the evidence for formulating the targeted strategy of malaria elimination.
Methods: The data of malaria cases in Jiangsu Province in 2016 were collected from China's Routine Diseases Surveillance Information System (CRDSIS).
Results: Totally, 239 imported malaria cases were reported in Jiangsu Province in 2017, and the cases decreased by 22.
Background: Plasmodium ovale is widely distributed across tropical regions and has two closely related but distinct species, namely P. ovale curtisi and P. ovale wallikeri.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
November 2018
Objective: To analyze the results of samples testing of Jiangsu Provincial Malaria Diagnostic Reference Laboratory in 2017, so as to provide the evidence for improving the malaria diagnostic performance in this province.
Methods: The samples of reported malaria cases in Jiangsu were collected by the provincial reference laboratory (PRL) in 2017. The microscopy and nucleic acid test were performed to confirm the infection of species of each case, while antigen tests (rapid diagnostic test, RDT) were performed as well.
Currently, malaria rapid diagnostic tests (RDTs) are widely used for malaria diagnosis, but test performance and the factors that lead to failure of Plasmodium ovale detection are not well understood. In this study, three pLDH-based RDTs were evaluated using cases in China that originated in Africa. The sensitivity of Wondfo Pf/Pan, CareStart pLDH PAN and SD BIOLINE Pf/Pan in P.
View Article and Find Full Text PDFImported malaria due to Plasmodium ovale curtisi and P. ovale wallikeri infections from African countries has increased recently (2011-2014) in Chinese travelers. We report novel genotypes, their prevalence and the predominant haplotypes of P.
View Article and Find Full Text PDFBackground: Plasmodium merozoite surface protein-1 (MSP-1) is released into the bloodstream during merozoite invasion, and thus represents a crucial malarial vaccine target. Although substantial research effort has been devoted to uncovering the genetic diversity of MSP-1 for P. falciparum and P.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
August 2018
Objective: To establish a systemized malaria biobank with well-rounded epidemiologic data and a computer-aid management system, thus to provide qualified sources for malaria elimination and human malaria research.
Methods: The malaria biobank was based on the platform of Jiangsu Institute of Parasitic Diseases. The blood smear samples, dried blood samples, whole blood samples and parasite strains isolated from patients (from both local and imported cases) were collected since 2011 according to a standardized operational procedure.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
April 2018
Objective: To analyze the working conditions and evaluate the effectiveness of blood smear examinations in fever patients after the start of national malaria elimination program (NMEP), and explore the suitable strategy for malaria diagnosis and surveillance in NMEP, so as to provide the evidence for the development and adaptation of malaria elimination strategies and measures in Jiangsu Province.
Methods: The data of malaria epidemic situation reported by network, fever patients' blood test tables, and epidemiological surveys of malaria cases were collected and statistically analyzed by SPSS 16.0 in Jiangsu Province from 2010 to 2016.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
August 2018
Objective: To understand the quality of production of blood slides and laboratory personnel's ability to microscopically examine at Jiangsu Province clinic inspection stations at all levels, so as to provide the evidence for the construction of malaria diagnostic laboratories and the evaluation of malaria elimination effect.
Methods: After the reexamination of the negative blood slides of the examination stations of the malaria center in each county (district), the negative blood slides of the outpatient inspection station in the district and all the positive blood slides of the direct report of the network from 2011 to 2017, the staining and cleanliness of the blood smears, microscopic examination results and the coincidence rate of positive blood species were comprehensively analyzed.
Results: A total of 19 109 checked blood samples were examined.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
August 2018
There were vivax malaria, falciparum malaria, and malariae malaria epidemic in Jiangsu Province, and vivax malaria was the dominant disease. and were malaria-transmitted vectors. Since the founding of People's Republic of China, there have been two major malaria outbreaks in Jiangsu Province, when the highest annual malaria incidence reached up to 24.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
April 2018
Objective: To explore the expression characteristics of cytochrome P450 (CYP) candidate genes (CYP6M3, CYP6Y1, CYP6P5, CYP4H14, CYP4G17, CYP12F16) in .
Methods: The samples were collected from different developmental stages (eggs, larvae, pupae and adult mosquitoes (females and males) ), and different tissues (salivary glands, malpighian tubes, midguts, ovaries, and fat bodies) of and the female adult mosquitoes exposed by different insecticide doses (0, 1.25, 3.
Background: Local malaria transmission has decreased rapidly since the National Malaria Elimination Action Plan was launched in China in 2010. However, imported malaria cases from Africa and Southeast Asia still occur in China due to overseas laborers. Diagnosis by microscopy is the gold standard for malaria and is used in most hospitals in China.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
February 2018
Objective: To understand the malaria epidemic situation and characteristics in Jiangsu Province in 2016, so as to provide the evidence for formulating and adjusting the strategy and measures for malaria elimination.
Methods: The data of malaria cases in Jiangsu Province in 2016 were collected from China's Routine Diseases Surveillance Information System (CRD-SIS) and analyzed statistically.
Results: Totally, 308 malaria cases were reported in Jiangsu Province in 2016, and the cases decreased by 23.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
August 2017
To understand the malaria epidemic situation and characteristics in Jiangsu Province in 2015, so as to provide the evidence for malaria elimination. The data of malaria cases in Jiangsu Province in 2015 were collected from China's routine diseases surveillance information system. Totally 405 imported cases were reported in Jiangsu Province in 2015, and the cases increased by 14.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
August 2017
Objective: To design and develop an online training and evaluation system for parasitic pathogen recognition.
Methods: The system was based on a Parasitic Diseases Specimen Image Digitization Construction Database by using MYSQL 5.0 as the system of database development software, and PHP 5 as the interface development language.