A nomogram of preoperative indicators predicting lymph vascular space invasion in cervical cancer.

Purpose: To develop predictive nomograms of lymph vascular space invasion (LVSI) in patients with early-stage cervical cancer.

Methods: We identified 403 patients with cervical cancer from the Affiliated Hospital of Jiangnan University from January 2015 to December 2019. Patients were divided into the training set (n = 242) and the validation set (n = 161), with patients in the training set subdivided into LVSI (+) and LVSI (-) groups according to postoperative pathology.

Efficacy and Safety of Niraparib as First-Line Maintenance Treatment for Patients with Advanced Ovarian Cancer: Real-World Data from a Multicenter Study in China.

Background: Poly (ADP-ribose) polymerase (PARP) inhibitors are a new maintenance therapy option for patients with ovarian cancer (OC).

Objective: To evaluate the efficacy and influencing factors of the novel PARP inhibitor niraparib for maintenance treatment of Chinese patients with advanced OC.

Patients And Methods: In this retrospective multicenter real-world study patients with advanced OC from 15 hospitals throughout China were enrolled.

Efficacy and Safety of Anlotinib in Overall and Disease-Specific Advanced Gynecological Cancer: A Real-World Study.

Purpose: Anlotinib is a novel oral small-molecule multi-target tyrosine kinase inhibitor that has been approved for treating non-small cell lung cancer. However, its efficacy and safety among patients with advanced gynecological cancer have not been comprehensively evaluated. We conducted this study to address this issue in the real-world setting.

Rare Vulvar Angiomyofibroblastoma: Case Series and Literature Review.

Background: Angiomyofibroblastoma (AMFB) is an uncommon disease with few literature reports, leading to the poor understanding of its diagnosis, treatment, and postoperative follow-up plans among gynecologists.

Objective: To study the clinical and pathological features of vulvar AMFB and discuss its treatment and prognosis.

Case Summary: The 3 cases were characterized by a gradually increasing painless mass in the vulva.

Research on the Road Performance of Asphalt Mixtures Based on Infrared Thermography.

Temperature segregation during the paving of asphalt pavements is one of the causes of asphalt pavement distress. Therefore, controlling the paving temperature is crucial in the construction of asphalt pavements. To quickly evaluate the road performance of asphalt mixtures during paving, in this work, we used unmanned aerial vehicle infrared thermal imaging technology to monitor the construction work.

Tumor suppressor miR-192-5p targets TRPM7 and inhibits proliferation and invasion in cervical cancer.

Cervical cancer is the fourth highest mortality cancer among women worldwide. Many researchers have discovered the major anticancer role of miR-192-5p. However, no study has revealed the effect of miR-192-5p on cervical cancer and its molecular mechanism.

The cross talk between cervical carcinoma cells and vascular endothelial cells mediated by IL-27 restrains angiogenesis.

Problem: To explore whether cervical carcinoma cell-derived interleukin-27 (IL-27) modulates the angiogenesis of vascular endothelial cells.

Method Of Study: The expression of IL-27 in cervical cancer tissues and cervical cell lines was analyzed by immunohistochemistry, ELISA and flow cytometry. Then, the effects of IL-27 on the proliferation and apoptosis-related molecules and angiogenesis in vitro of human umbilical vein endothelial cells (HUVECs) were investigated.