Endobronchial Therapy With Gentamicin and Dexamethasone After Airway Clearance by Bronchoscopy in Exacerbation of Non-Cystic Fibrosis Bronchiectasis: A Real-World Observational Study.

The exacerbation of non-cystic fibrosis bronchiectasis (NCFB) may lead to poor prognosis. The objective of this study was to retrospectively analyze the clinical efficacy and safety of endobronchial therapy with gentamicin and dexamethasone after airway clearance by bronchoscopy in the exacerbation of NCFB. We retrospectively reviewed 2,156 patients with NCFB between January 2015 and June 2016 and 367 consecutive patients with exacerbation of bronchiectasis who had complete data and underwent airway clearance (AC) by bronchoscopy.

[Efficacy of semicircular canal occlusion in the treatment of fifteen pateints with Meniere's disease].

To investigate the long-term efficacy of semicircular canal occlusion in the treatment of refractory Meniere's disease. Fifteen patients with Meniere's disease who underwent semicircular canal occlusion were reviewed. The preoperative and postoperative frequency of vertigo ,quality of life, hearing and tinnitus level were compared.

Benign paroxysmal positional vertigo secondary to laparoscopic surgery.

Objectives: Benign paroxysmal positional vertigo is a common vestibular disorder and it may be idiopathic or secondary to some conditions such as surgery, but rare following laparoscopic surgery.

Methods: We report two cases of benign paroxysmal positional vertigo secondary to laparoscopic surgery, one after laparoscopic cholecystectomy in a 51-year-old man and another following laparoscopic hysterectomy in a 60-year-old woman.

Results: Both patients were treated successfully with manual or device-assisted canalith repositioning maneuvers, with no recurrence on the follow-up of 6 -18 months.

[Cinical and genetic characteristics of familial Meniere's disease: three families report].

Objective: To investigate the clinical and genetic characteristics of three Chinese Meniere's disease (MD) families and decipher the mechanism of MD further.

Methods: Personal and family medical evidence of hearing loss, vestibular symptoms, and other clinical abnormalities of the participants were identified, clinical and genetic features were analyzed. Targeted 307 genes capture and high-throughput sequencing were performed on the two ascertained members of family 1007184.

[Study of clinical characteristics and curative effects of sudden hearing loss patients with vertigo].

Objective: To analyze the clinical characteristics, prognosis and therapeutic effects of sudden sensorineural hearing loss (SSHL) patients associated with vertigo, and to investigate the strategy of diagnosis and treatment.

Methods: We retrospectively analyzed the clinical characteristics of 240 patients diagnosed as SSHL with vertigo, who were treated in the Chinese PLA General Hospital from July 2008 to August 2012. Various factors affecting the therapeutic effects were analyzed, such as audiological features, vestibular function tests, genders, audiograms, lasting before seeing a doctor, courses of vertigo and vascular factors.

Relationship between nutritional risk and exercise capacity in severe chronic obstructive pulmonary disease in male patients.

Objective: The nutritional status of chronic obstructive pulmonary disease (COPD) patients is associated with their exercise capacity. In the present study, we have explored the relationship between nutritional risk and exercise capacity in severe male COPD patients.

Methods: A total of 58 severe COPD male patients were enrolled in this study.

Efficacy of Computer-Controlled and Modified Roll Maneuver for Treatment of Geotropic Lateral Canal Benign Paroxysmal Positional Vertigo.

Objective: To evaluate the short-term efficacy of computer-controlled and modified roll maneuver (CMRM) versus conventional roll maneuver (RM) for treatment of geotropic lateral canal benign paroxysmal positional vertigo (BPPV).

Study Design: Prospective case-controlled study.

Setting: Academic hospital.

Efficacy of computer-controlled repositioning procedure for benign paroxysmal positional vertigo.

Objectives/hypothesis: To evaluate the short-term efficacy of the computer-controlled canalith repositioning procedure (CRP) for treatment of posterior canal benign paroxysmal positional vertigo (BPPV) compared with the current standard CRP.

Study Design: Prospective case series.

Methods: One hundred thirty-two patients diagnosed as having idiopathic posterior canal BPPV, with an age range of 28 to 86 years (mean 56 years), 47 men and 85 women, were treated with computer-controlled CRP mimicking the Epley maneuver.

[Anatomical measurements and clinical applications through facial recess approach].

Objective: To provide the anatomic data for the correlated otologic microsurgery by the microdissection of temporal bone through facial recess approach.

Method: Sixteen human temporal bones of eight adult cadaveric heads were dissected under surgical microscope through facial recess approach, and the relative anatomic structures were observed and measured, such as the bony entrance of facial recess approach, facial nerve, stapes, round window, round window niche, pyramidal eminence, cochleariform process, etc. The data were analyzed statistically.

[Clinical characteristics and surgical management of extensive cholesteatoma of external auditory canal].

Objective: To classify the external auditory canal cholesteatoma(EACC) by high-resolution temporal bone CT scans and the clinical findings of the patients, and to discuss the clinical and imaging characteristics and the surgical management of the extensive EACC.

Method: A retrospective study was carried out among 56 patients (58 ears) with EACC and their clinical data were carefully analyzed. We classified EACC as the extensive type and the localized type.

[Clinical analysis of bilateral same-day myringoplasty for 22 cases with bilateral tympanic membrane perforation].

Objective: To investigate the feasibility of bilateral same-day myringoplasty and the indications for myringoplasty for patients with bilateral tympanic membrane perforation, and to summarize relevant experience.

Methods: Twenty-two patients underwent bilateral same-day underlay myringoplasty, and all cases were consistent with the indications for myringoplasty. The preoperative hearing and postoperative hearing at three months were compared, and the postoperative symptoms and complications were observed.

[Functional analysis of the vertical semicircular canal using vertical plane swing test and study of its normal values].

Objective: The purpose of this study was to set up a method to analyze the vertical semicircular canal function and study the normal values of the vertical semicircular canal function using the vertical plane swing test.

Methods: A prospective analysis of 100 normal persons (aged from 18 to 59 years), who were treated by using the vertical plane swing test with the newly developed automatic vestibular function diagnosis and therapy system (SRM-IV). These persons were rotated 180° at a sinusoidal speed (acceleration 45°/s, maximum speed 90°/s) in the vertical semicircular canal plane.

[Operation of hypopharyngeal carcinoma with restrained vocal cord motility].

Objective: To explore the feasibility of laryngeal function preservation in surgical treatment of hypopharyngeal carcinoma with restrained vocal cord motility.

Methods: Twenty-six cases of hypopharyngeal carcinoma treated with conservative hypopharyngectomy were retrospectively analyzed. Partial resection of pyriform sinus and partial laryngectomy were performed.

[Molecular etiology of non-syndromic hearing impairment in a Chinese family].

Objective: To investigate the molecular etiology of non-syndromic hearing impairment in two patients in a maternal inherited deafness Chinese family.

Methods: Peripheral blood specimens were collected and DNA templates extracted. The complete mitochondrial genomes and GJB2 gene were sequenced in an ABI 3100 Avant sequencer.

[Applied study of voice function rehabilitation by mucosa tube performed in operation of late laryngocarcinoma.].

Objective: To study the voice function rehabilitation by mucosa tube performed in operation of late laryngocarcinoma and to improve the survival quality of patients with late laryngocarcinoma.

Methods: Forty-six patients were treated between Oct. 1991 and May 2006, including 41 males and 5 females.

[Analysis and application of the images from the segmenting CT in the space of nasal endoscope].

Objective: To analyze the images from the segmenting CT in the space of nasal endoscope and to observe the benefits in applying the method in endoscopic sinus surgery.

Methods: Five patients with inverted papilloma and ten patients with chronic rhinosinusitis were enrolled. The images from the coronal CT were put in the ideal model of the nasal cavity, which had been designed by SketchUp software package, and the space of the model in the 0 degree rod-lens telescope was simulated and observed according to definite elevation angle between the endoscope and bottom of nasal cavity and the distance of the endoscope entering the nasal cavity.

[Three-axis otoconia maneuver treatment in benign paroxysmal positional vertigo].

Objective: To evaluate three-axis otoconia maneuver (TOM) for benign paroxysmal positional vertigo (BPPV).

Methods: The data from twenty BPPV patients who received three-axis otoconia maneuver treatment and 20 BPPV patients who received canalith repositioning (CRP) maneuver treatment were analyzed retrospectively.

Results: There were 17 patients received 1 TOM session and 3 patients received 2 TOM sessions while 16 patients received 1 CRP session and 4 patients received 2 CRP sessions.

[The value of computed tomography scans of temporal bone and eustachian tubal function tests for lesions at tympanic opening of eustachian tube in middle ear cholesteatoma].

Objective: To investigate the value of high resolution computed tomography (HRCT) of temporal bone and eustachian tubal function tests for lesions at tympanic opening of eustachian tube in the patients of otitis media with cholesteatoma prior to surgery.

Method: The clinical data of 38 cases (41 ears) with cholesteatoma, which were examined by HRCT scans and eustachian tubal function tests before mastoidectomy (29 ears) or mastoidectomy+ tympanoplasty (12 ears), were analyzed.

Result: The rate of conformation between the radiographic and the operative findings was 94.