Publications by authors named "Xiyu Ruan"
Background: The long-term exposure to ultraviolet radiation (UVR) raises oxidative stress and chronic inflammation levels, which in turn has a series of deleterious effects on skin health, such as sunburn, photoaging, and skin cancer. Hence, our study was determined to investigate the effects and mechanisms of epigallocatechin gallate (EGCG) in zebrafish and human skin fibroblasts (HSF) cells to alleviate ultraviolet-induced photoaging.
Methods: The 4 days postfertilization (dpf) zebrafish larvae and HSF cells were treated with 10 J/cm UVA + 30 mJ/cm UVB, or 25, or 50 M EGCG for 72 hr.