Zero-Dimensional Plastic Phase Transition Iron-Based Compounds with High and Switchable SHG Responses.

Organic-inorganic hybrid materials have garnered significant interest due to their unique combination of phase transition characteristics, substantial entropy changes, simple preparation methods, and structural flexibility, making them promising candidates for applications in sensor technologies and data storage systems. In the present research, two plastic organic-inorganic hybrid phase transition materials: [CHNF]FeCl () and [CHNF]FeBr () were successfully synthesized by the H/F substitution strategy. Significant step-like dielectric changes were observed during the reversible phase transitions of (401 K) and (406 K).

Preliminary findings of DNA hypermethylation of MDGA1 in idiopathic restless legs syndrome.

Background: Both genetic and environmental factors contribute to the development of restless legs syndrome (RLS). Epigenetic mechanisms might play a vital role in RLS but remain underexplored. MDGA1, involved in synaptic inhibition, has been identified by genome-wide association studies as a potential risk gene for RLS.

The impact of undergraduate nursing students' time management disposition on innovative behavior: the chain mediating role of academic self-efficacy and flow experience.

Objective: To explore the chain intermediary effect of academic self-efficacy and flow experience of undergraduate nursing students in the influence mechanism of time management disposition on innovative behavior.

Methods: Seven hundred and sixty-three undergraduate nursing students from 3 universities in Jiangsu Province were investigated with Adolescent time Management Disposition Scale, Academic Self-efficacy Scale, Flow Short Scale and Innovation Behavior Scale. The chain intermediary model was constructed and verified.

Risk factors and prognosis of acute ischemic stroke related restless legs syndrome.

Background: Recent studies suggest that stroke may be associated with an increased prevalence of restless legs syndrome (RLS) as a comorbidity or a risk factor. We aimed to explore the association between acute ischemic stroke (AIS) and RLS, and the possible pathogenesis of acute ischemic stroke related restless legs syndrome (AIS-RLS), for guiding its diagnosis and treatment.

Methods: In this single-center, prospective study, we identified consecutive AIS patients and segregated into AIS-RLS group and non-AIS-RLS group based on the diagnostic criteria of RLS.

Acoustic prosodic parameters associated with Parkinson's disease cognitive impairment.

Background: Acoustic prosodic analysis is a novel approach that can be used to identify patients with mild cognitive impairment (MCI) and dementia in Alzheimer's disease (AD). We hypothesize that acoustic analysis can also differentiate cognitive impairment in Parkinson's disease (PD).

Methods: We investigated acoustic parameters in 90 subjects including 30 PD with normal cognition (PD-NC), 30 PD with mild cognitive impairment (PD-MCI) and 30 PD with dementia (PDD).

Liposomes-Loaded miR-9-5p Alleviated Hypoxia-Ischemia-Induced Mitochondrial Oxidative Stress by Targeting ZBTB20 to Inhibiting Nrf2/Keap1 Interaction in Neonatal Mice.

Hypoxia ischemia (HI) is a leading cause of cerebral palsy and long-term neurological sequelae in infants. Given that mitochondrial dysfunction in neurons contributes to HI brain damage, this study aimed to investigate the regulatory role of miR-9-5p in mitochondrial function following HI injury. Overexpression of miR-9-5p in HI mice or HO-exposed PC12 cells suppressed neuronal injury, associated with increased mitochondrial copy number, normalizing mitochondrial membrane potential, improved nuclear factor-erythroid factor 2-related factor 2 (Nrf2) activation, and downregulation of Keap1.

Destabilization of Single-Atom Catalysts: Characterization, Mechanisms, and Regeneration Strategies.

Numerous in situ characterization studies have focused on revealing the catalytic mechanisms of single-atom catalysts (SACs), providing a theoretical basis for their rational design. Although research is relatively limited, the stability of SACs under long-term operating conditions is equally important and a prerequisite for their real-world energy applications, such as fuel cells and water electrolyzers. Recently, there has been a rise in in situ characterization studies on the destabilization and regeneration of SACs; however, timely and comprehensive summaries that provide the catalysis community with valuable insights and research directions are still lacking.

Survival benefit associated with liver transplantation for hepatocellular carcinoma based on tumor burden scores at listing.

Introduction: Liver transplantation (LT) provides significant survival benefits to patients with unresectable HCC. In the United States, organ allocation policies for HCCs within the United Network for Organ Sharing criteria do not prioritize patients based on their differences in oncological characteristics. This study assessed whether transplant-associated survival benefits (TASBs) vary among patients with different tumor burden scores (TBS) measured at the time of listing.

Enhancing astaxanthin accumulation in immobilized Haematococcus pluvialis via alginate hydrogel membrane.

Immobilized cultivation is anticipated to be effective for enhancing both biomass and astaxanthin accumulation in Haematococcus pluvialis (H. pluvialis). A novel fabrication method of alginate hydrogel membrane (AHM) was introduced for immobilized cultivation of H.

Targeted and non-targeted proteomics to identify the urinary protein biomarkers for Wilson disease.

Background: Wilson disease (WD) is a genetic disorder of copper metabolism. Early diagnosis of WD is inherently challenging due to the absence of typical symptoms. This study aimed to identify urinary protein biomarkers for WD using targeted and nontargeted mass spectrometry-based approaches.

A Complex Oxide Containing Inherent Peroxide Ions for Catalyzing Oxygen Evolution Reactions in Acid.

Proton exchange membrane water electrolyzers powered by sustainable energy represent a cutting-edge technology for renewable hydrogen generation, while slow anodic oxygen evolution reaction (OER) kinetics still remains a formidable obstacle that necessitates basic comprehension for facilitating electrocatalysts' design. Here, we report a low-iridium complex oxide LaSrIrO with a unique hexagonal structure consisting of isolated Ir(V)O octahedra and true peroxide O groups as a highly active and stable OER electrocatalyst under acidic conditions. Remarkably, LaSrIrO, containing 59 wt % less iridium relative to the benchmark IrO, shows about an order of magnitude higher mass activity, 6-folds higher intrinsic activity than the latter, and also surpasses the state-of-the-art Ir-based oxides ever reported.

Comparative effects of four types of resistant starch on the techno-functional properties of low-fat meat emulsions.

The behavior of resistant starch (RS) in meat matrix depends largely on its type. Hence, the comparative impacts of high amylose corn starch (RS2), retrograded starch (RS3), acetylated starch (RS4) and high amylose-lauric acid complex (RS5) on water-fat binding capacities, texture, color and microstructure of low-fat meat emulsions were investigated. Four types of RS improved water retention, emulsion stability, textural properties and brightness of low-fat meat emulsions, displaying even better potential than inulin (positive control).

Probing Selenium-Deficient Chicken Spleen Th1/Th17 Differentiation Based on Selenoprotein W Targeting of PKM2/HIF1α.

Selenium regulates the differentiation and function of immune cells mainly through selenoproteins. Selenoprotein W (SelW) has been shown to mitigate inflammatory bowel disease in mice by modulating the differentiation of helper T (CD4 T) cell. Previous studies by our team have underscored SelW's critical role in safeguarding chicken spleens and splenic lymphocytes against inflammatory injury.

HS improves hippocampal synaptic plasticity in SPS rats via PI3K/AKT signaling pathway.

Post-traumatic stress disorder (PTSD) is a severe mental illness that could impose heavy burdens on individuals and society, but effective and precise treatment modalities are unknown. The level of hydrogen sulfide (HS) in the brain plays an important role in psychiatric diseases. However, it is still unclear whether PTSD exposure could affect the level of HS and whether there is a correlation between HS levels and the pathogenesis of PTSD.

DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.

Background: Studies have shown that Averrhoa carambola L. possesses therapeutic potential for diabetes and related complications. However, the specific beneficial effects and molecular mechanisms of 2-dodecyl-6-meth-oxycyclohexa-2,5-diene-1,4-dione (DMDD) isolated from Averrhoa carambola L.

Ketoprofen promotes the conjugative transfer of antibiotic resistance among antibiotic resistant bacteria in natural aqueous environments.

The emergence and spread of antibiotic resistance in the environment pose a serious threat to global public health. It is acknowledged that non-antibiotic stresses, including disinfectants, pharmaceuticals and organic pollutants, play a crucial role in horizontal transmission of antibiotic resistance genes (ARGs). Despite the widespread presence of non-steroidal anti-inflammatory drugs (NSAIDs), notably in surface water, their contributions to the transfer of ARGs have not been systematically explored.

Correlating active sites and oxidative species in single-atom catalyzed Fenton-like reactions.

Single-atom catalysts (SACs) have gained widespread popularity in heterogeneous catalysis-based advanced oxidation processes (AOPs), owing to their optimal metal atom utilization efficiency and excellent recyclability by triggering reactive oxidative species (ROS) for target pollutant oxidation in water. Systematic summaries regarding the correlation between the active sites, catalytic activity, and reactive species of SACs have rarely been reported. This review provides an overview of the catalytic performance of carbon- and metal oxide-supported SACs in Fenton-like reactions, as well as the different oxidation pathways induced by the metal and non-metal active sites, including radical-based pathways (, ·OH and SO˙) and nonradical-based pathways ( O, high-valent metal-oxo species, and direct electron transfer).

Identification, expression, and characterization of a marine-derived chitinase Ce0303 from Chitiniphilus eburneus YS-30 with exo- and endo-hydrolytic properties.

N-acetyl-oligosaccharides exhibit antioxidant and antibacterial activities. However, the low catalytic efficiency of chitinase on crystalline chitin hinders the eco-friendly production of N-acetyl-oligosaccharides. A marine-derived chitinase-producing strain Chitiniphilus eburneus YS-30 was screened in this study.

Crystal-Phase-Selective Etching of Heterophase Au Nanostructures.

Selective oxidative etching is one of the most effective ways to prepare hollow nanostructures and nanocrystals with specific exposed facets. The mechanism of selective etching in noble metal nanostructures mainly relies on the different reactivity of metal components and the distinct surface energy of multimetallic nanostructures. Recently, phase engineering of nanomaterials (PEN) offers new opportunities for the preparation of unique heterostructures, including heterophase nanostructures.

From electricity to vitality: the emerging use of piezoelectric materials in tissue regeneration.

The unique ability of piezoelectric materials to generate electricity spontaneously has attracted widespread interest in the medical field. In addition to the ability to convert mechanical stress into electrical energy, piezoelectric materials offer the advantages of high sensitivity, stability, accuracy and low power consumption. Because of these characteristics, they are widely applied in devices such as sensors, controllers and actuators.