Unlocking the power of multi-institutional data: Integrating and harmonizing genomic data across institutions.

Cancer is a complex disease driven by genomic alterations, and tumor sequencing is becoming a mainstay of clinical care for cancer patients. The emergence of multi-institution sequencing data presents a powerful resource for learning real-world evidence to enhance precision oncology. GENIE BPC, led by American Association for Cancer Research, establishes a unique database linking genomic data with clinical information for patients treated at multiple cancer centers.

Reducing catheter-related bloodstream infections using Lean Six Sigma methodology.

Background: Central venous catheters (CVC) are used for dialysis in end-stage renal disease patients, presenting a significant risk for Catheter-Related Bloodstream Infections (CRBSI). While Lean Six Sigma has been effective in reducing CRBSI, its efficacy outside intensive care units (ICU) remains less explored. This study aims to evaluate the effectiveness of Lean Six Sigma in mitigating CRBSI risks among non-ICU hemodialysis patients.

Investigation into the thermal comfort and physiological adaptability of outdoor physical training in college students.

Over the last few decades, increase in global temperatures have led to a deterioration in the quality of open spaces, urban vitality, and public health. Strenuous physical training under hot conditions outdoors increases the potential for developing heat illnesses. It is therefore necessary to examine the relationships between human physiological indices, psychological responses, and outdoor thermal indices to predict and evaluate human thermal safety in hot environments.

Au@Carbon quantum Dots-MXene nanocomposite as an electrochemical sensor for sensitive detection of nitrite.

A highly sensitive electrochemical sensor was developed through a one-pot green synthesis method for nitrite detection based on the electrochemical technique. Xylan-based carbon quantum dots (CQDs) were used as green in situ reducing agent to prepare CQDs capped gold nanoparticles (Au@CQDs). MXene of good electrical conductivity was used as the immobilized matrix to fabricate Au@CQDs-MXene nanocomposites with the advantages of good electrical conductivity and electrocatalysis.

Investigation into outdoor thermal comfort conditions by different seasonal field surveys in China, Guangzhou.

Outdoor microclimatic conditions strongly affect the thermal comfort of pedestrians. A transversal field survey was conducted in Guangzhou, together with micrometeorological measurements. The outdoor physiological equivalent temperature (PET) varied from 3 to 59 °C.