A systematic review and meta-analysis of the effect of transitional care interventions on the prognosis of patients with heart failure.

Background: The purpose of this study was to explore the impact of transitional care interventions on the prognosis of patients with heart failure.

Methods: Literature on transitional care interventions in patients with heart failure were retrieved from PubMed, Medline, Embase, and CENTRAL databases. The literature retrieval date was October 12, 2021.

Asymmetric Silica Nanoparticles with Tailored Spiky Coverage Derived from Silica-Polymer Cooperative Assembly for Enhanced Hemocompatibility and Gene Delivery.

Asymmetric mesoporous silica nanoparticles (AMSNs) with one side featuring a spiky nanotopography, while the other side is smooth and solid, were synthesized via an ethylenediamine (EDA)-directed silica-polymer cooperative assembly approach. By simply varying the EDA amount (), AMSNs- samples with adjustable spiky surface coverage were obtained. It is demonstrated that a spiky coverage higher than 50% improved the hemocompatibility of AMSN-, possibly due to the reduced contact area of the smooth side exposed to the red blood cell (RBC) membrane.

Formation of aluminum diphosphonate mesostructures: The effect of aluminum source.

Mesostructured aluminum phosphonates (AOP-x) bridging with 1,1'-hydroxyl ethylidene groups, including a lamellar mesostructure (AOP-N) with crystalline framework, a well-ordered 2D-hexagonal mesophase (AOP-Cl), and a particle-packed mesostructure (AOP-S), were simply synthesized in the presence of surfactant cetyltrimethylammonium bromide in the ethanol-water system, by choosing Al(NO), AlCl and Al(SO) as the aluminum source, respectively. The crystallinity, morphology, mesophase, and skeletal structure of the as-prepared materials were characterized by XRD, TEM, SEM, Al, P and C MAS NMR, and nitrogen sorption techniques. After calcination under N at 350 °C, the calcined AOP-x samples consist of aluminum phosphonate and phosphate, possessing desirable specific surface areas of 116-585 m/g.

MiR-10a improves hepatic fibrosis by regulating the TGFβl/Smads signal transduction pathway.

The aim of the present study was to examine the expression variation of the mouse hepatic fibrosis tissue transforming growth factor (TGF)-βl/Smads signal transduction pathway and its correlation with progression of hepatic fibrosis. The promotion effect of microRNA (miR)-10a on hepatic fibrosis and its possible mechanism was also assessed. Forty healthy female 8-week-old C57BL6/J mice were randomly divided into the control group (intraperitoneal injection of 5 µl/g normal saline, twice per week for 8 weeks) and the hepatic fibrosis group (intraperitoneal injection of 5 µl/g 10% CCI4 olive oil, twice per week for 8 weeks), with 20 mice per group.

Increasing the H+ exchange capacity of porous titanium phosphonate materials by protecting defective P-OH groups.

Hierarchically macro-/mesoporous titanium phosphonates with enlarged H(+) exchange capacity were synthesized in the presence of a series of alkyl amines that acted as protective groups for the defective P-OH, which were used as promising solid acid catalysts to replace conventional liquid acid catalysts and acidic resins in some acid-catalytic reactions.

Hierarchical mesostructured titanium phosphonates with unusual uniform lines of macropores.

Organic-inorganic hybrid materials of mesostructured titanium phosphonates with unusual uniform lines of macropores were synthesized by using bis(hexamethylenetriamine) penta(methylenephosphonic acid) (BHMTPMP) as the coupling molecule, through a one-pot hydrothermal process without any surfactant assistance. A wormhole-like mesostructure and many uniform parallel lines of macropores divided by solid ridges in the same direction were confirmed by N(2) sorption, SEM and TEM observations. This novel macropore architecture has never been observed in other metal phosphonate materials, which may be directly related to the structure nature of BHMTPMP with extra long alkyl chains.

Cubic mesoporous titanium phosphonates with multifunctionality.

Cubic mesoporous titanium phosphonate materials with bridged organic groups inside the framework were synthesized by means of a one-pot hydrothermal autoclaving process, with the assistance of cationic surfactant cetyltrimethylammonium bromide. 1-Hydroxyethylidene-1,1-diphosphonic acid was used as the coupling molecule. A typical cubic mesophase with surface area of 1052 m(2) g(-1) and pore size of 2.

[A fluorospectrophotometric determination of nitrite in blood].

Aim: To establish a fluorospectrophotometric assay for the measurement of nitrite in blood.

Methods: Interference from hemoglobin and other blood ingredients was removed through sulfuric acid and phosphotungstic acid pretreatment. Fluorescence of 1-[H]-naphthotriazole from the reaction of 2,3-diaminonaphthalene with nitrite was determined with fluorospectrophotometry.