Resveratrol Reestablishes Mitochondrial Quality Control in Myocardial Ischemia/Reperfusion Injury through Sirt1/Sirt3-Mfn2-Parkin-PGC-1α Pathway.

Resveratrol is a natural polyphenol found in various plants. It has been widely studied on cardiovascular disorders. It is known that resveratrol can activate Sirtuin proteins and participate in cellular energy metabolism through a Sirtuin-dependent pathway.

Mesoporous Ti O Nanosheets with High Polar Surface Area for Catalyzing Separator to Reduce the Shuttle Effect of Soluble Polysulfides in Lithium-sulfur Batteries.

In the effort to accelerate adsorption and catalytic conversion of lithium polysulfides (Li-PSs) and suppress the shuttle effect of lithium-sulfur batteries (LSBs), the Ti O nanosheets/carbon material-modified separator is successfully fabricated to reducing soluble Li-PSs' crossover from cathode to anode. The catalyst of mesoporous Ti O nanosheets with O-Ti-O units synthesized at low temperature shows both excellent conductivity and high surface area. The modified separator can serve as a diffusion barrier of Li-PSs and catalyst for converting soluble low-chain sulfides into insoluble ones and then remarkably enhance the sulfur utilization and electrochemical performance of the LSB.

OxyR-Like Improves Cell Hydrogen Peroxide Tolerance by Participating in Monocyte Chemotaxis and Oxidative Phosphorylation Regulation in MSR-1.

The formation of magnetosomes inside magnetotactic bacteria is a complex process strictly controlled by the intracellular metabolic regulatory system. A series of transcriptional regulators are involved in the biosynthesis of the magnetosome, including OxyR-Like protein, which is indispensable for the maturation of magnetosomes in MSR-1. In this study, a new function of the OxyR-Like protein that helps cells resist reactive oxygen species (ROS) was identified.

Three-dimensional layered double hydroxide membranes: fabrication technique, growth mechanism, and enhanced photocatalytic activity.

Novel three-dimensional ZnAl-LDH/AAO and NiAl-LDH/AAO membranes using porous anodic aluminum oxide (AAO) templates as a substrate and an Al3+ source were successfully fabricated via a simple precipitant-free in situ growth technique. These membranes with uniform layered double hydroxide (LDH) plates on the outer and inner surfaces exhibit enhanced activities in photocatalysis.

The formation mechanism and photocatalytic activity of hierarchical NiAl-LDH films on an Al substrate prepared under acidic conditions.

NiAl-LDH films with hierarchical morphology have been fabricated by immersion of an Al substrate in Ni(2+)-containing solutions under strong acidic conditions, and the growth processes of the films are discussed in this communication. The as-prepared LDH films exhibit high activity in the photocatalytic degradation of organic contaminants.

[Physicochemical properties and skin penetration in vitro of total alkaloids of Sophora flavescens nanoemulsion].

The research aimed at investigating the physicochemical properties, stability and skin penetration in vitro of total alkaloids of Sophora flavescens nanoemulsion. Prepare total alkaloids of S. flavescens nanoemulsion and detect the determination of matrine and oxymatrine in the nanoemulsion using HPLC method.

[Preparation of Kushen-Dilong nanoemulsion gel and transdermal characterization in vitro].

Objective: To prepare Kushen-Dilong nanoemulsion and nanoemuls-ion gel, and investigate its content, physical and chemical properties. Their transdermal properties in vitro were studied as well.

Method: IPM acted as oil phase, EL35 as surfactant, EtOH as cosurfactant, Pheretima aqueous solution was added dropwise to the oil phase to prepare Kushen-Dilong nanoemulsion at room temperature using magnetic stirring.

The stability investigation of compound Danshen injection (a traditional medicine) with a new high-performance liquid chromatography method.

Background: Compound Danshen injection (CDSI, a traditional medicine) is an effective drug for the treatment of cardiovascular and cerebrovascular diseases. However, the research about its stability is absent.

Objective: A new high-performance liquid chromatography method was developed to assay its main effective constituents, i.

Effect of Kushen (Radix Sophorae flavescentis) extract on laryngeal neoplasm Hep2 cells.

Objective: To evaluate the effect of fermented extract of Kushen (Radix Sophorae Flavescentis) or non-fermented ESF on laryngeal neoplasms Hep2 cells.

Methods: Use 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay to explore the effect of fermented ESF and non-fermented ESF on Hep2 cells, and detect the mRNA and protein expression level of Bcl-2, Bax and Caspase-3 with reverse transcription polymerase chain reaction (RT-PCR) and Western blot.

Results: Both fermented ESF and non-fermented ESF could inhibit laryngeal neoplasm's Hep2 cells, but and the cells did not response to the dilution 1: 320 of fermented ESF, nor to the 1:1280 dilution of non-fermented ESF.