The health effects of traffic-derived pollutants have gathered increasing concerns. Our objectives were to evaluate the associations of traffic-related heavy metal exposure with serum uric acid (SUA) and hyperuricemia and to explore the underlying mechanism. Traffic-related heavy metals (including zinc, iron, manganese, copper, lead, cadmium, antimony, and barium) and SUA were determined among 3909 community-based adults from the Wuhan-Zhuhai cohort.
View Article and Find Full Text PDFThe associations of polycyclic aromatic hydrocarbon (PAH) exposure with serum uric acid (SUA) or hyperuricemia have been rarely assessed. We aimed to investigate the relationships between urinary PAH metabolites and SUA or hyperuricemia among US adults and to explore the mediating role of systemic inflammation in the associations. A total of 10,307 US adults were conducted to assess the associations of seven urinary hydroxy‑PAH with SUA and hyperuricemia and evaluate the role of C-reactive protein (CRP), a biomarker of systemic inflammation, in such associations.
View Article and Find Full Text PDFExposure of dichlorodiphenyltrichloroethane (DDT) pesticide was suggested to be associated with adverse effects on the respiratory system. However, the effects of DDT exposure on lung function remain unclear. Our objectives were to investigate the potential associations of internal levels of DDT and its metabolites including dichlorodiphenyldichloroethylene (DDE) and dichlorodiphenyldichloroethane (DDD) with lung function.
View Article and Find Full Text PDFAdverse health effects of ambient ozone are getting widespread attention, but the evidence on the relationship between ozone levels and circulatory system diseases are limited and inconsistent. Daily data for ambient ozone levels and hospitalizations for total circulatory diseases and five subtypes in Ganzhou, China from January 1, 2016 to December 31, 2020 were collected. We constructed a generalized additive model with quasi-Poisson regression accounting for lag effects to estimate the associations between ambient ozone levels and the number of hospitalized cases of total circulatory diseases and five subtypes.
View Article and Find Full Text PDFObjective: Previous epidemiological studies have shown that both long-term and short-term exposure to fine particulate matters (PM) were associated with the morbidity and mortality of circulatory system diseases (CSD). However, the impact of PM on CSD remains inconclusive. This study aimed to investigate the associations between PM and circulatory system diseases in Ganzhou.
View Article and Find Full Text PDF