: The formula Chong-Lou-Yao-Fang (CLYF) is an herbal medicinal formulation developed by the indigenous Naxi people for treating liver cancer. This study was to reveal the biological activity, potential targets, and molecular mechanisms of CLYF for cancer treatment. : Network pharmacology, microarray data analysis, survival analysis, and molecular docking were employed to predict potential compounds, targets, and pathways for the treatment of liver cancer.
View Article and Find Full Text PDFThe traditional medicinal knowledge in the northwest of Yunnan Province, China have been poorly studied. var. (PPvY) is widely cultivated and used as indigenous traditional Chinese medicine (TCM) to treat cancer in northwest Yunnan.
View Article and Find Full Text PDFCancer is one of the top two leading causes of death worldwide. Ethnobotanical research, it is one of methods, which is able to discover effective anticancer drugs based on "prototype" of indigenous people's historical experiences and practices. The rhizomes of var.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
September 2022
Steroidal saponins, important natural organic compounds in Paris polyphylla var. yunnanensis, have good biological activity. Structural modification of steroidal saponins by microbial transformation could produce a large number of products with novel structures and excellent bioactivity, which can provide functional compounds for the research and development of steroidal drugs.
View Article and Find Full Text PDFThe orchid Dendrobium officinale grows throughout southeast China and southeast Asian countries and is used to treat inflammation and diabetes in traditional Chinese medicine. Tie pi feng dou is a well-known traditional Chinese medicine made from the dried D. officinale stems.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
December 2021
This paper reviewed the traditional use of Paris polyphylla and its active components, aiming to provide reference for the development and utilization of this plant. It was found that P. polyphylla has been used as a medicinal plant by eight ethnic minorities.
View Article and Find Full Text PDFHumans have dyed textiles and leather, colored food, and paint body parts using natural dyes throughout history. Natural dyes have suffered drastically due to recent socioeconomic changes and replacement with synthetic dye in the textile industry. Hence, it is urgent to study indigenous dye plants and dyeing craft in local communities to protect these resources' potential ecological, economic, and cultural values.
View Article and Find Full Text PDFA strategy to the 6-5-6 tricyclic scaffold of taiwaniaquinoids was established on the basis of a one-pot thermal ring expansion/4π-electrocyclization process. The efficiency of this methodology has been demonstrated through its application in the total synthesis of taiwaniaquinone H, which has been accomplished in three steps and 14% overall yield in a protecting-group-free manner starting from commercially available materials.
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