Publications by authors named "Xiuxia Lian"
Article Synopsis
- Non-alcoholic fatty liver disease and type 2 diabetes mellitus are linked to insulin resistance (IR), but there are no approved drugs to target IR, even though Alpinia officinarum (A. officinarum) may help with diabetes treatment.
- The study aimed to identify the active components of A. officinarum and explore how it affects insulin resistance using network pharmacology and molecular docking, alongside in vitro testing on liver cells.
- Researchers found 14 key active components in A. officinarum, with A14 being the most promising one, and revealed it may help reduce oxidative stress and improve insulin resistance via specific biological pathways.
AHP-3a, a triple-helix acidic polysaccharide isolated from Hance, was evaluated for its anticancer and antioxidant activities. The physicochemical properties and structure of AHP-3a were investigated through gel permeation chromatography, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy. The weight-average molecular weight of AHP-3a was 484 kDa, with the molar percentages of GalA, Gal, Ara, Xyl, Rha, Glc, GlcA, and Fuc being 35.
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