Reparative effects after low-dose radiation exposure: Inhibition of atherosclerosis by reducing NETs release.

Objective: The cardiovascular system effects of environmental low-dose radiation exposure on radiation practitioners remain uncertain and require further investigation. The aim of this study was to initially investigate and explore the mechanisms by which low-dose radiation may contribute to atherosclerosis through a multi-omics joint comprehensive basic experiment.

Methods: We used WGCNA and differential analyses to identify shared genes and potential pathways between radiation injury and atherosclerosis sequencing datasets, as well as tissue transcriptome immune infiltration level extrapolation and single-cell transcriptome data correction using the CIBERSORT deconvolution algorithm.

Streptavidin-Conjugated DNA for the Boronate Affinity-Based Detection of Poly(ADP-Ribose) Polymerase-1 with Improved Sensitivity.

This work reports the development of a fluorescence method for the detection of poly(ADP-ribose) polymerase-1 (PARP1), in which a phenylboronic acid-modified fluorescein isothiocyanate dye (FITC-PBA) was used to recognize the formed poly(ADP-ribose) (PAR) polymer. The detection system was designed by conjugating recombinant streptavidin (rSA) with PARP1-specific double-stranded DNA (dsDNA) through streptavidin-biotin interaction. Capture of PARP1 via rSA-biotin-dsDNA allowed for the poly-ADP-ribosylation (PARylation) of both rSA and PARP1 in a homogeneous solution.

Pain and Prescription Opioid Use Among US Construction Workers: Findings From the 2011‒2018 Medical Expenditure Panel Survey.

To examine prescription opioid and nonopioid analgesic use among US construction workers and their associations with pain conditions and sociodemographic factors. We analyzed data for about 9000 (weighted 11.5 million per year) construction workers who responded to the Medical Expenditure Panel Survey from 2011 to 2018.

Injury inequalities among U.S. construction workers.

This study explores racial/ethnic inequalities in work-related injuries among U.S. construction workers.

Musculoskeletal Disorders and Prescription Opioid Use Among U.S. Construction Workers.

Background: Musculoskeletal disorders (MSDs) and opioid use are a combined burden for construction safety and health. This study examines both issues among construction workers using a large population-based survey.

Methods: The prevalence of MSDs in construction was estimated using multi-year data from the Medical Expenditure Panel Survey.

Health Risk Behavior Profile of Construction Workers, 32 States, 2013 to 2016.

Background: Research has suggested that several health risk behaviors were more prevalent among construction workers than among the general workforce.

Methods: The prevalences of six health risk behaviors among construction workers were compared with workers in other industries using data from 32 states in the 2013 to 2016 Behavioral Risk Factor Surveillance System (BRFSS).

Results: Smoking, smokeless tobacco use, binge drinking, no leisure-time physical activity, and not always using a seatbelt were significantly more prevalent (P < 0.

Prescription opioid use and associated factors among US construction workers.

Background: Construction workers are among the segments of the US population that were hit hardest by the opioid prescription and overdose deaths in the past decades. Factors that underlie opioid use in construction workers have been compartmentalized and isolated in existing studies of opioid use and opioid overdose, but they ignore the overall context of their use. This study examines prescription opioid use and its association with a variety of occupational and nonoccupational factors in construction workers in the United States.

Building a Sustainable Construction Workforce.

The average U.S. construction worker is aged 42.

Heat-related deaths among construction workers in the United States.

Background: Heat is a severe hazard for construction workers and may be worsening with global warming. This study sought to explore heat-related deaths among U.S.

Construction Safety and Health in the USA: Lessons From a Decade of Turmoil.

The construction industry is one of the largest and also most hazardous industries in the USA. It is affected more severely by the business cycle than most other industries. We examined industry trends during the last decade including the severe recession.

The construction FACE database - Codifying the NIOSH FACE reports.

Introduction: The National Institute for Occupational Safety and Health (NIOSH) has published reports detailing the results of investigations on selected work-related fatalities through the Fatality Assessment and Control Evaluation (FACE) program since 1982.

Method: Information from construction-related FACE reports was coded into the Construction FACE Database (CFD). Use of the CFD was illustrated by analyzing major CFD variables.

Baby boomers in the United States: Factors associated with working longer and delaying retirement.

Objectives: This study estimated the self-reported probability of working full-time past age 62 (P62) or age 65 (P65) among four cohorts of Americans born between 1931 and 1959.

Methods: Data from the Health and Retirement Study (HRS) were analyzed. Respondents in four age cohorts were selected for comparison.

Fatal falls and PFAS use in the construction industry: Findings from the NIOSH FACE reports.

This study analyzed the Construction FACE Database (CFD), a quantitative database developed from reports of the Fatality Assessment and Control Evaluation (FACE) program conducted by the National Institute for Occupational Safety and Health (NIOSH). The CFD contains detailed data on 768 fatalities in the construction industry reported by NIOSH and individual states from 1982 through June 30, 2015. The results show that falls accounted for 42% (325) of the 768 fatalities included in the CFD.

Work-related musculoskeletal disorders among construction workers in the United States from 1992 to 2014.

Objectives: Examine trends and patterns of work-related musculoskeletal disorders (WMSDs) among construction workers in the USA, with an emphasis on older workers.

Methods: WMSDs were identified from the 1992-2014 Survey of Occupational Injuries and Illnesses (SOII), and employment was estimated from the Current Population Survey (CPS). Risk of WMSDs was measured by number of WMSDs per 10 000 full-time equivalent workers and stratified by major demographic and employment subgroups.

Respiratory Cancer and Non-Malignant Respiratory Disease-Related Mortality among Older Construction Workers-Findings from the Health and Retirement Study.

Objective: This study explored the risk of respiratory cancer and non-malignant respiratory disease (NMRD)-related mortality among older construction workers.

Methods: Analyzed data from the 1992-2010 RAND Health and Retirement Study (HRS) and the HRS National Death Index - Cause of Death file. About 25,183 workers aged 50 years and older were examined, including 5,447 decedents and 19,736 survivors, of which 1,460 reported their longest job was in construction.

Economic consequences of workplace injuries in the United States: Findings from the National Longitudinal Survey of Youth (NLSY79).

Background: This study explored economic consequences of work-related injuries using a longitudinal data source.

Methods: Data were from the National Longitudinal Survey of Youth, 1979 cohort (n = 12,686). Short-term consequences were measured when the injury was reported.

Occupational and non-occupational factors associated with work-related injuries among construction workers in the USA.

Background: Many factors contribute to occupational injuries. However, these factors have been compartmentalized and isolated in most studies.

Objective: To examine the relationship between work-related injuries and multiple occupational and non-occupational factors among construction workers in the USA.

Long-term health outcomes of work-related injuries among construction workers--findings from the National Longitudinal Survey of Youth.

Background: This study examined the relationship between work-related injuries and health outcomes among a cohort of blue-collar construction workers.

Materials And Methods: Data were from the National Longitudinal Survey of Youth, 1979 cohort (NLSY79; n = 12,686). A range of health outcomes among blue-collar construction workers (n = 1,435) were measured when they turned age 40 (1998-2006) and stratified by these workers' prior work-related injury status between 1988 and 2000.

Risks of a lifetime in construction. Part II: Chronic occupational diseases.

Background: We developed working-life estimates of risk for dust-related occupational lung disease, COPD, and hearing loss based on the experience of the Building Trades National Medical Screening Program in order to (1) demonstrate the value of estimates of lifetime risk, and (2) make lifetime risk estimates for common conditions among construction workers.

Methods: Estimates of lifetime risk were performed based on 12,742 radiographic evaluations, 12,679 spirometry tests, and 11,793 audiograms.

Results: Over a 45-year working life, 16% of construction workers developed COPD, 11% developed parenchymal radiological abnormality, and 73.

Risks of a lifetime in construction part I: traumatic injuries.

Background: Estimates of occupational risk are typically computed on an annual basis. In contrast, this article provides estimates of lifetime risks for fatal and nonfatal injuries among construction workers. A companion paper presents lifetime risks for occupational illnesses.

Fatal falls in the U.S. residential construction industry.

Background: Falls from heights remain the most common cause of workplace fatalities among residential construction workers in the United States.

Methods: This paper examines patterns and trends of fall fatalities in U.S.

Using O*NET to estimate the association between work exposures and chronic diseases.

Background: A standardized process using data from the Occupational Information Network (O*NET) is applied to estimate the association between long-term aggregated occupational exposure and the risk of contracting chronic diseases later in life. We demonstrate this process by analyzing relationships between O*NET physical work demand ratings and arthritis onset over a 32-year period.

Methods: The National Longitudinal Survey of Youth provided job histories and chronic disease data.

A novel method for estimating the effects of job conditions on asthma and chronic lung disease.

Objective: This study uses 32 years of longitudinal job history to analyze the long-term effect of exposure to specific workplace conditions on the risk of contracting asthma or chronic lung disease later in life. Our approach allows for the estimation of occupational respiratory risks even in the absence of direct environmental monitoring.

Methods: We employ a novel methodology utilizing data from the National Longitudinal Survey of Youth 1979 (NLSY79), and ratings of job exposures from the Occupational Information Network (O*NET), which are based on 70 years of empirical data compiled by the U.

Fatal falls from roofs among U.S. construction workers.

Introduction: This study examined trends and patterns of fatal falls from roofs in the U.S. construction industry over an 18-year period (1992-2009), with detailed analysis for 2003-2009.