Does the coupling of digital and green technology innovation matter for carbon emissions?

The global situation of carbon reduction is very severe, and the coupling of digital and green technology innovation is one of the most significant approaches to promoting regional low-carbon transformation. A coupling evaluation model is employed to assess the coupling index between digital technology innovation and green technology innovation in China's 30 provinces from 2011 to 2021. The STIRPAT model is used to examine the impact of the increasing coupling index on carbon emissions, as well as its spatial effects, and heterogeneity.

Research trends and hot topics of wearable sensors in wound care over past 18 years: A bibliometric analysis.

Objective: This study determined the development trends, analyzed collaboration networks, and identified research hotspots in the field of wearable sensors for wound care from 2007 to 2024 using a rigorous bibliometric analysis approach.

Methods: Bibliometric and scientometric analyses were performed utilizing data sourced from the Web of Science Core Collection database. This study examined publication trends, contributions from various countries and institutions, author productivity, keyword prevalence, and citation patterns to discern research hotspots and potential future avenues in the application of wearable sensors for wound care.

Composited sea surface responses to tropical cyclones in the Bay of Bengal during 2003-2020.

Tropical cyclones (TCs) in the Bay of Bengal (BoB) caused significant changes in the sea surface as they passed through the sea. To quantitatively study the differences in oceanic responses caused by TCs during pre-monsoon and post-monsoon seasons in the BoB from 2003 to 2020 and the varying importance of TC intensity and translation speed in modulating oceanic responses, the oceanic environmental parameters affected by TCs were composited and analyzed. The spatial distributions show that the responses of sea surface temperature (SST) rather than chlorophyll-a (Chl-a) concentrations and sea surface salinity (SSS) coincided with the maximum response centers of the wind power index (WPi).

Targeted regulation of miR-154-5p/Cullin2 pathway by hsa_circ_TRIM22 in promoting human papillomavirus 16 positive cervical cancer progression.

Tripartite motif-containing 22 (TRIM22) is characterized by a canonical RING domain with ubiquitin E3 ligase activity and is closely associated with tumorigenesis. As a product of TRIM22 transcription, whether hsa_circ_TRIM22 has a function of regulating tumorigenesis is unclear. Thus, we aimed to explore the role and mechanism of hsa_circ_TRIM22 in human papillomavirus (HPV) 16 positive cervical cancer (CC).

Competition between ocean thermal structure and tropical cyclone characteristics modulates ocean environmental responses in the Yellow and Bohai Seas.

To study the environmental responses of tropical cyclones (TCs) in continental shelf regions, TCs passing over the Yellow Sea and Bohai Sea (YBS) during 2002-2020 were investigated, with a special focus on how competition between ocean thermal structure and TC characteristics modulates ocean surface changes. The spatial distributions of the climatic mixed layer depth (MLD), accumulated wind forcing power index (WPi), accumulated sea surface temperature (SST) changes and accumulated chlorophyll (Chl-a) changes in the YBS were calculated. The linear regressions indicate that both the TC-induced SST cooling and TC-induced Chl-a increase are correlated with the TC wind speed rather than the translation speed, especially when the TC forcing depth (Z) is greater than the MLD.

Comprehensive analysis of WOX transcription factors provide insight into genes related to the regulation of unisexual flowers development in Akebia trifoliata.

Akebia trifoliata is a fascinating economic and medicinal plant that produces functionally unisexual flowers due to stamen/pistil abortion during flower development, and the genetic regulation pathway of this process remain completely unknown. Here, 10 AktWOXs were identified for the first time, all contained a highly conserved homeodomain. AktWOXs were divided into three clades, each with the same or similar intron, exon, and motifs distribution.

Injectable Xenogeneic Dental Pulp Decellularized Extracellular Matrix Hydrogel Promotes Functional Dental Pulp Regeneration.

The present challenge in dental pulp tissue engineering scaffold materials lies in the development of tissue-specific scaffolds that are conducive to an optimal regenerative microenvironment and capable of accommodating intricate root canal systems. This study utilized porcine dental pulp to derive the decellularized extracellular matrix (dECM) via appropriate decellularization protocols. The resultant dECM was dissolved in an acid pepsin solution to form dECM hydrogels.

MicroRNA-154-5p suppresses cervical carcinoma growth and metastasis by silencing Cullin2 and .

Background: MicroRNA-154-5p (miR-154-5p) plays a role in tumorigenesis in diverse human malignancies. Nevertheless, little is known about the mechanism by which miR-154-5p alters the growth and metastasis of cervical cancer. This research aimed to analyze the role of miR-154-5p in the pathology of cervical cancer and .

The hsa_circ_0000276-ceRNA regulatory network and immune infiltration in cervical cancer.

Background: Our previous studies have confirmed that miR-154-5p can regulate pRb expression, and thus, play a tumor suppressor role in HPV16 E7-induced cervical cancer. However, its upstream molecules have not been elucidated in the progression of cervical cancer. This study aimed to explore the role of the miR-154-5p upstream molecule, hsa_circ_0000276 in cervical cancer development and its possible mechanisms of action.

Pharmacological Activation of YAP/TAZ by Targeting LATS1/2 Enhances Periodontal Tissue Regeneration in a Murine Model.

Due to their multi-differentiation potential, periodontal ligament fibroblasts (PDLF) play pivotal roles in periodontal tissue regeneration in vivo. Several in vitro studies have suggested that PDLFs can transmit mechanical stress into favorable basic cellular functions. However, the application of mechanical force for periodontal regeneration therapy is not expected to exhibit an effective prognosis since mechanical forces, such as traumatic occlusion, also exacerbate periodontal tissue degeneration and loss.

Strategies of cell and cell-free therapies for periodontal regeneration: the state of the art.

Background: Periodontitis often causes irrevocable destruction of tooth-supporting tissues and eventually leads to tooth loss. Currently, stem cell-based tissue engineering has achieved a favorable result in regenerating periodontal tissues. Moreover, cell-free therapies that aim to facilitate the recruitment of resident repair cell populations to injured sites by promoting cell mobilization and homing have become alternative options to cell therapy.

High-accuracy model recognition method of mobile device based on weighted feature similarity.

Accurately model recognition of mobile device is of great significance for identifying copycat device and protecting intellectual property rights. Although existing methods have realized high-accuracy recognition about device's category and brand, the accuracy of model recognition still needs to be improved. For that, we propose Recognizer, a high-accuracy model recognition method of mobile device based on weighted feature similarity.

A 3D-Bioprinted Functional Module Based on Decellularized Extracellular Matrix Bioink for Periodontal Regeneration.

Poor fiber orientation and mismatched bone-ligament interface fusion have plagued the regeneration of periodontal defects by cell-based scaffolds. A 3D bioprinted biomimetic periodontal module is designed with high architectural integrity using a methacrylate gelatin/decellularized extracellular matrix (GelMA/dECM) cell-laden bioink. The module presents favorable mechanical properties and orientation guidance by high-precision topographical cues and provides a biochemical environment conducive to regulating encapsulated cell behavior.

Ion Flux Self-Regulation Strategy with a Volume-Responsive Separator for Lithium Metal Batteries.

Lithium metal batteries (LMBs) are regarded as one of the most promising next-generation energy storage devices due to their high energy density. However, the conversion of LMBs from laboratory to factory is hindered by the formation of lithium dendrites and volume change during lithium stripping and deposition processes. In this work, a volume-responsive separator with core/shell structure thermoplastic polyurethane (TPU)/polyvinylidene fluoride (PVDF) fibers and SiO coating layers is designed to restrict dendrite growth.

Lack of association between and polymorphisms and the risk of multiple sclerosis: a meta-analysis from 37 studies.

Background: Epidemiological studies about the association between genetic polymorphisms in , and and the risk for multiple sclerosis (MS) have been performed extensively. However, the results are inconclusive. The purpose of this meta-analysis was to evaluate the contribution of the polymorphisms in , and to the susceptibility of MS.

Green Initiatives and Environmental Concern Foster Environmental Sustainability: A Study Based on the Use of Reusable Drink Cups.

Unsustainable production and consumption have threatened human life and nature. Therefore, practitioners around the globe have paid attention to sustainability issues and adopted pro-environmental strategies to protect the environment. Using single-use cups contributes to environmental pollution.

Proposing a Robust Model to Reduce Employees' Turnover Intentions in an Ethical Leadership Framework: Empirical Evidence from the Healthcare Sector.

Employee turnover is expensive and disruptive for an organization. Studies have already mentioned that the economic cost of turnover is huge, ranging from 90% to 200% of the existing employee's salary. With an increase in turnover rate, the social fabric of an enterprise may be disrupted.

Development of a Promising F-Radiotracer for PET Imaging Legumain Activity In Vivo.

Legumain has been found overexpressed in several cancers, which serves as an important biomarker for cancer diagnosis. In this research, a novel fluorine-18 labeled radioactive tracer [18F]SF-AAN targeting legumain was designed and synthesized for positron emission tomography (PET) imaging. Nonradioactive probe [19F]SF-AAN was obtained through chemical and solid phase peptide synthesis.

Opportunities and challenges: mesenchymal stem cells in the treatment of multiple sclerosis.

Multiple sclerosis (MS) was once considered an untreatable disease. Through years of research, many drugs have been discovered and are widely used for the treatment of MS. However, the current treatment can only alleviate the clinical symptoms of MS and has serious side effects.

Multiparameter measurement sensor based on no-core fiber.

This paper proposes a no-core-single-mode-no-core Mach-Zehnder fiber sensor. In this sensor, two no-core fibers serve as input and output couplers, and the middle single-mode fiber serves as a sensing arm. Using finite element simulation and theoretical analysis, the optimal length of the couplers and the sensing arm are determined.

Stimuli-Responsive Macrocyclization Scaffold Allows Self-Assembly of Radioactive Tracers for Positron Emission Tomography Imaging of Enzyme Activity.

Target-enabled bioorthogonal reaction and self-assembly of a small-molecule probe into supramolecules have shown promise for molecular imaging. In this paper, we report a new stimuli-responsive bioorthogonal reaction scaffold () for controlling self-assembly by engineering the condensation reaction between 2-cyanobenzothiazole and cysteine. For probes with the scaffold, intramolecular cyclization took place soon after activation, which could efficiently outcompete free cysteine even at a low concentration and result in efficient aggregation in the target.

Exploring Green Creativity: The Effects of Green Transformational Leadership, Green Innovation Climate, and Green Autonomy.

None of the studies published in the extant literature has discussed the role of green innovation climate and green autonomy concerning green creativity and this study aims to offer these two novel constructs. By introducing the componential theory of creativity, this study explores green transformational leadership (GTL), green innovation climate, and green autonomy as antecedents of green creativity. The authors employed structural equation modeling (SEM) to analyze survey-based data collected from automotive firms in China.

Promising potential of a F-labelled small-molecular radiotracer to evaluate PD-L1 expression in tumors by PET imaging.

Programmed death ligand 1 (PD-L1) expression level is a reproducible biomarker for guiding stratification of patients to immunotherapy. However, the most widely used immunohistochemistry method is incompetent to fully understand the PD-L1 expression level in the whole body because of the highly complex PD-L1 expression in the tumor microenvironment. In this work, a novel small-molecular radiotracer [F]LG-1 based on the biphenyl active structure was developed to evaluate PD-L1 expression in tumors.

Development of biotin-tagged near-infrared fluorescence probes for tumor-specific imaging.

Near-infrared (NIR) probes are applicable for tumor imaging due to deep tissue penetration and low background signal. And cyanine dyes with long emission wavelength are excellent fluorophores to develop NIR probes. However, the aggregation of cyanine dyes in aqueous solution reduces the utilization of light.