Publications by authors named "Xiuru Gong"
Purpose: Noninvasive assessment of significant liver fibrosis in rabbits by spectral CT parameters and texture analysis.
Materials And Methods: Thirty-three rabbits were randomly divided into 27 carbon tetrachloride-induced liver fibrosis group and 6 control group. Spectral CT contrast-enhanced scan was performed in batches, and the liver fibrosis was staged according to the histopathological results.
Background: This study aimed to perform a meta-analysis to evaluate the diagnostic performance of radiomics in predicting axillary lymph node metastasis (ALNM) and sentinel lymph node metastasis (SLNM) in breast cancer.
Materials And Methods: Multiple electronic databases were systematically searched to identify relevant studies published before April 29, 2022: PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, and Wanfang Data. The quality of the included studies was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool.
Background: High expression of copper metabolizing MURR1 domain (COMMD3) is significantly correlated with poor prognosis in hepatocellular carcinoma (HCC) patients. Here, we explored the mechanism by which COMMD3 affects HCC angiogenesis through the HIF1/VEGF/NF-B signaling pathway.
Methods: SK-Hep1 and Hep-3B cell lines were transfected by overexpression and RNA interference lentivirus and verified using RT-qPCR and western blotting techniques.
Article Synopsis
- The study compares the effectiveness of transient elastography (TE) and two-dimensional shear wave elastography (2D-SWE) in diagnosing liver fibrosis in children and adolescents through a review of existing research.
- A total of 27 studies with nearly 2000 patients showed that both TE and 2D-SWE have high sensitivity and specificity for detecting all stages of liver fibrosis, particularly advanced fibrosis and cirrhosis.
- The findings suggest that these non-invasive imaging techniques are reliable alternatives to liver biopsy, especially for higher levels of liver fibrosis.