Serum monocyte chemotactic protein 1 and soluble mannose receptor aid predictive diagnosis of pediatric sepsis.

Background: To investigate the value of serum monocyte chemotactic protein 1 (MCP-1) and soluble mannose receptor (sMR) for predictive diagnosis of pediatric sepsis.

Methods: This study retrospectively analyzed the data of 82 children with acute and severe signs of inflammation. According to the diagnostic criteria of sepsis, these children were divided into a sepsis group (40 cases) and a non-sepsis group (42 cases).

Asymmetric Michael reaction of 3-homoacyl coumarins with chromone-fused dienes toward enantioenriched coumarin chromone skeletons.

Asymmetric Michael reaction of 3-homoacyl coumarins and chromone-fused dienes was developed by employing a chiral squaramide, and a series of coumarin chromone skeletons were furnished in moderate to high yields (up to 99%) and stereoselectivities (up to 98 : 2 dr, 99% ee).

[Simultaneous analysis of iodate, iodide, bromate and bromide by ion chromatography with ultraviolet detection].

An analytical method of ion chromatography with ultraviolet detection has been developed and applied for the simultaneous determination of iodate, iodide, bromate and bromide. The separation was performed on a quaternary ammonium type anion exchange column with citric acid and acetonitrile as mobile phase. The effects of the detection wavelength, the kind and concentration of the mobile phase and other parameters on separation and detection of the four ions were investigated.