Effect of Thermal Aging on Mechanical Properties and Morphology of GF/PBT Composites.

The effects of thermal aging at 85~145 °C in air on the tensile and flexural mechanical properties of 20% glass fiber (GF)-reinforced commercial grade polybutylene terephthalate (PBT) composites were studied. The results showed that as the aging temperature increased, the tensile and flexural strength of the GF/PBT composites significantly decreased. However, the elastic modulus of the composites was almost independent of aging.

Guided multi-scale refinement network for camouflaged object detection.

The purpose of camouflaged object detection (COD) is to identify the hidden camouflaged object in an input image. Compared with other binary segmentation tasks like salient object detection, COD needs to deal with more complex scenes, such as low contrast, similar foreground and background. In this work, we proposed a novel guided multi-scale refinement network for COD.

Regulation of TRPV1 channel in monosodium urate-induced gouty arthritis in mice.

Objective: The transient receptor potential vanilloid subtype 1 (TRPV1) channel is considered to play an important regulatory role in the process of pain. The purpose of this study is to observe the change characteristics of TRPV1 channel in MSU-induced gouty arthritis and to find a new target for clinical treatment of gout pain.

Methods: Acute gouty arthritis was induced by injection of monosodium urate (MSU) crystals into the ankle joint of mice.

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain.

Substance P contributes to the pathogenesis of pain by acting on NK-1R, specialized sensory neurons that detect noxious stimuli. Aprepitant, an antagonist of NK-1R, is widely used to treat chemotherapy-induced nausea and vomiting. In this study, we used LPS-stimulated BV-2 microglia cell line and animal models of inflammatory pain to explore the analgesic effect of aprepitant on inflammatory pain and its underlying mechanism.

Magnolol attenuates inflammatory pain by inhibiting sodium currents in mouse dorsal root ganglion neurons.

Voltage-gated sodium channels are currently recognized as one of the targets of analgesics. Magnolol (Mag), an active component isolated from Magnolia officinalis, has been reported to exhibit analgesic effects. The objective of this study was to investigate whether the analgesic effect of Mag was associated with blocking Na channels.

Modulations of Na1.8 and Na1.9 Channels in Monosodium Urate-Induced Gouty Arthritis in Mice.

The aim of the present study was to observe the changes of TTX-R, Na1.8, and Na1.9 Na currents in MSU-induced gouty arthritis mice, and to explore the possibility of Na1.

Hydrophilic/Hydrophobic Heterogeneity Anti-Biofouling Hydrogels with Well-Regulated Rehydration.

Hydrogels, as a representative of soft and biocompatible materials, have been widely used in biosensors, biomedical devices, soft robotics, and the marine industry. However, the ir-recoverability of hydrogels after dehydration, which causes the loss of original mechanical, optical, and wetting properties, has severely restricted their practical applications. At present, this critical challenge of maintaining hydrogels' accurate character has attracted less attention.