Publications by authors named "Xiuping Lai"

Sluggish status of green technology development has stimulated research into new incentives and pathways. Beyond the traditional regulatory-push and demand-pull approaches, we reposition the strength of the technology push. Based on the innovation diffusion theory, a multidimensional path model of knowledge spillover in universities is constructed, and the impact of heterogeneous knowledge spillover channels on green innovation activities of local firms is discussed.

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This study aimed to analyze and discuss the biomarkers of PEGylated liposomal doxorubicin (PLD) injection-induced hypersensitivity reactions (HSRs) in advanced breast cancer patients. Fourteen patients from Sun Yat-sen Memorial Hospital were included in the study between April 15th, 2020 and April 14th, 2021. Patient plasma was collected 30 min before PLD injection.

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Article Synopsis
  • KN026 is a new bispecific antibody that targets two different HER2 sites and was tested for safety, effectiveness, and potential biomarkers in patients with HER2-positive metastatic breast cancer.
  • In a phase I study involving 63 female patients who had not responded to prior HER2 treatments, various doses of KN026 were administered, with 20 mg/kg and 30 mg/kg showing promising results in efficacy.
  • The treatment was generally well tolerated, with common side effects like fever and diarrhea, and the study identified co-amplification of HER2 and CDK12 as a potential biomarker for better patient response to KN026.
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The purpose of this study was to evaluate whether test cefradine capsules and reference cefradine capsules were bioequivalent in healthy Chinese volunteers. An open-label, randomized, biperiodic, crossover design was used. In each of the 2 study periods (separated by a 1-week washout period), 250-mg single doses of either the test or reference cefradine capsule were administered to study participants under fasted and fed conditions.

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The pursuit of flood prevention safety and the mitigation of drainage contradiction against an unnecessary influx of floodwater require a modern and efficient model to optimize the management of the initial allocation of flood drainage rights. We attempted to formulate a framework for initial flood drainage rights allocation to promote the sustainable drainage of the Sunan Canal, China. The Pressure-State-Response (PSR) model was constructed using a literature review and interviews with experts and directors using 18 key indicators being determined from field surveys and library studies.

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