Publications by authors named "Xiuming He"

Osteoarthritis (OA) is a progressively developing condition primarily characterized by the deterioration of articular cartilage and the proliferation of bone, along with ongoing inflammation. Although the precise pathogenesis remains somewhat elusive, restoring the homeostatic balance of the intra-articular microenvironment is crucial for the management of OA. Intra-articular injection of medication is one of the most direct and effective treatment methods; however, most injectable drugs used for osteoarthritis treatment, due to their rapid breakdown, quick release, poor biological activity, and frequent injections, leading to increased risk of infection and suboptimal therapeutic outcomes.

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Spinal facet joint osteoarthritis (FJOA) is an OA disease with pathogenesis and progression uncovered. Our present study was performed to elucidate the role of DNM3OS on spinal FJOA. In this study, spine facet joint tissue of patients were collected.

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Article Synopsis
  • The Functional Movement Screen (FMS) is commonly used to identify movement deficiencies in athletes, but its effectiveness in detecting issues in knee osteoarthritis (KOA) has not been thoroughly studied.
  • This research involved 45 individuals with varying grades of KOA and 15 healthy controls, who performed FMS tasks and daily activities while being recorded by a markerless motion capture system.
  • Results indicated that the FMS was more sensitive than daily activities in detecting movement anomalies, particularly highlighting knee flexion and trunk angles during the in-line lunge as key indicators for assessing KOA.
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