Publications by authors named "Xiulong Zhong"
Article Synopsis
- - This study investigates how the LINC00663/EBF1/NR2F1 pathway influences inflammation and blood vessel formation (angiogenesis) in bladder cancer.
- - Researchers performed various experiments, including cell tests and animal studies, showing that higher levels of LINC00663 and NR2F1 are linked to more aggressive cancer traits, such as cell growth and invasiveness.
- - Silencing LINC00663 led to decreased NR2F1 levels and reduced cancer-related processes, suggesting that LINC00663 plays a crucial role in promoting inflammation and angiogenesis in bladder cancer through its regulation of NR2F1 via EBF1.
Background: Recent studies have revealed the significant roles of immune-related long noncoding RNAs (lncRNAs) in cancer development and progression. The identification of biomarkers that contribute to early detection and risk stratification provides significant benefits for bladder cancer (BC) patients. The current study aimed to determine an immune-related lncRNA signature for predicting the prognosis of BC patients.
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- Overexpression of eIF5A2 in various cancers is linked to increased tumor cell migration and invasion, raising questions about its role as a treatment target in prostate cancer (PCa).
- This study utilized specific RNA techniques to lower eIF5A2 levels in prostate cancer cells and in animal models, assessing effects on cell behavior and tumor progression.
- Findings revealed that reducing eIF5A2 led to decreased cell migration, increased apoptosis, and lower tumor growth and metastasis, suggesting that targeting eIF5A2 may be a promising approach for PCa treatment.
Background: Recent studies have demonstrated that immune-associated genes (IAGs) play an important role in the occurrence and progression of clear renal clear cell carcinoma (ccRCC). Novel biomarkers and a reliable prognostic prediction model for ccRCC patients are still limited. The objective of this study was to develop a IAGs signature and validate its prognostic value in ccRCC using bioinformatic methods and publicly database.
View Article and Find Full Text PDFNephrolithiasis accelerates the renal failure in the patients with ADPKD. In order to evaluate the role of percutaneous nephrolithotomy in management of calculus in these patients, 11 patients with autosomal dominant polycystic kidney disease and renal stones were included in the study. Two patients had bilateral renal stones.
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