Clinical characteristics of pediatric inpatients infected with the SARS-CoV-2 Omicron variant-a retrospective observational cohort study.

Background: The children infected with the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are at risk of progressing to severe disease. Clinical characteristics treatment measures and prognosis of these special age group of patients have not been completely understood which necessitate more researches. This study sought to analyze the clinical characteristics of children infected with the Omicron variant to provide evidences for the prevention, diagnosis and treatment of the Omicron variant infection in children.

[Study of hospitalization risk indicators for intensive care unit patients evaluated by intelligent calculation method].

Objective: To explore the characteristics of the changes in risk score for intensive care unit (ICU) patients during hospitalization by the intelligent calculation method, and to provide evidence for the risk prevention.

Methods: In this retrospective study, ICU patients of the Fifth Central Hospital in Tianjin from November 3, 2021 to March 28, 2022 were enrolled and divided into ≥ 14 days group, 10-13 days group, 7-9 days group, and 3-6 days group according to the ICU length of stay. Risk scores assessed by the intelligent calculation method of the ICU patients were collected, including nutritional risk screening 2002 (NRS 2002), Caprini score and Padua score.

[Control study of the intelligent calculation method and the traditional calculation method in risk assessments of hospitalization].

Objective: To explore the accuracy of intelligent calculation (IC) method for risk assessment of hospitalization for patients, aiming to build a more advantageous risk assessment system.

Methods: The "Search Engine" program was developed based on hospital information system (HIS) of the Fifth Center Hospital in Tianjin, which automatically captured patient information and generated nutritional risk screening 2002 (NRS 2002) score, Caprini thrombosis risk assessment model and Padua thrombosis risk assessment model for venous thromboembolism (VTE), the CHADS-VASc for predicting stroke risk stratification in atrial fibrillation and the HAS-BLED for predicting bleeding risk in anticoagulated patients with atrial fibrillation. A randomized controlled trial was conducted.

Risk Factors of Recurrent Stroke in Young and Middle-Aged Stroke Patients after Interventional Therapy.

Objective: To explore the risk factors of recurrent stroke in young and middle-aged stroke patients after interventional therapy.

Methods: Retrospective analysis was conducted on the data of 300 young and middle-aged stroke patients treated in our hospital (February 2015-February 2017). All patients received interventional therapy.

[A clinical study on the determination of cuff pressure in artificial airway by minimum air leakage method].

Objective: To compare the cuff pressure and leakage volume and the related complications of filling the tracheal tube cuff by minimum air leakage method and cuff pressure manometer method after endotracheal intubation, so as to provide theoretical basis for patients who was intubated to obtain appropriate cuff pressure.

Methods: A prospective randomized controlled study was conducted. 100 patients admitted to the department of critical care medicine of the Fifth Center Hospital in Tianjin from December 2015 to June 2019 were enrolled.

Comparison of early and delayed removal of dressing following primary closure of clean and contaminated surgical wounds: A systematic review and meta-analysis of randomized controlled trials.

The usefulness of dressing a surgical wound beyond the first 24-48 h of surgery is currently a controversial issue. The aim of this meta-analysis was to compare the early and delayed removal of dressing following primary closure in the management of clean and contaminated surgical wounds. Systematic searches were conducted in various databases including Medline, Cochrane Controlled Register of Trials (CENTRAL), Scopus, and Embase from January, 1964 until October, 2019.

[The influence of joining central venous catheter and pressure transducer with T-junctions on central venous pressure].

Objective: To investigate the influence of the number of T-junctions between central venous catheter and pressure transducer on measurement of central venous pressure ( CVP ) in patients.

Methods: A prospective controlled study was conducted. The patients with CVP monitoring in Department of Critical Care Medicine of the Fifth Center Hospital in Tianjin from February to October in 2014 were enrolled.

"Expiratory holding" approach in measuring end-expiratory pulmonary artery wedge pressure for mechanically ventilated patients.

Objective: To accurately measure the end-expiratory pulmonary artery wedge pressure (PAWP) with the "expiration holding" function on the ventilator and the "pulmonary artery wedge pressure review" software on the monitor.

Materials And Methods: Fifty prospective measurements were made on 12 patients undergoing pulmonary artery catheter and mechanical ventilation. All measurements were divided into <8 mmHg or ≥8 mmHg subgroups according to respiratory variability, and they were then subdivided into either an airway pressure display measurement group (AM group) or an expiration holding (EH) group for comparison.

[The impact of early restrictive positive fluid balance strategy on the prognosis of patients with severe trauma].

Objective: To observe the impact of early restrictive positive fluid balance strategy on the prognosis of patients with trauma.

Methods: A prospective controlled study was conducted. The patients with severe post-trauma capillary leak syndrome (PTCLS) admitted to department of critical care medicine of the Fifth Center Hospital in Tianjin were considered as study object.

[The application of "expiration holding" in measuring end expiration pulmonary artery wedge pressure in patients undergoing mechanical ventilation].

Objective: To find an accurate and convenient method of measuring end expiratory pulmonary artery wedge pressure (eePAWP) by "expiration holding" function of ventilator and "pulmonary artery wedge pressure (PAWP) Review" software of monitor.

Methods: Twelve patients with introduction of pulmonary artery catheter and undergoing mechanical ventilation were selected. Fifty measurements were randomly selected for the comparison of the differences between automatic measurement and expiration holding method in each patient.