Phantom study and clinical application of total-body F-FDG PET/CT imaging: How to use small voxel imaging better?

Background: Conventional PET/CT imaging reconstruction is typically performed using voxel size of 3.0-4.0 mm in three axes.

One-tenth-activity total-body positron emission tomography versus full-activity imaging in patients with a complex of hepatic malignant tumors: a retrospective study.

Background: The value of ultra-low-activity 2-[F]-fluoro-2-deoxy-D-glucose (F-FDG) positron emission tomography (PET) imaging in patients with hepatic malignancies remains unclear.

Methods: A cross-sectional study was conducted from April 2019 to May 2021 in Zhongshan Hospital, Fudan University. A total of 49 patients with hepatic malignancies, including hepatocellular carcinoma (HCC) (n=13) or intrahepatic cholangiocarcinoma (ICC) (n=36), underwent 60-min dynamic PET imaging, with 15 undergoing full-activity F-FDG and 34 undergoing ultra-low-activity F-FDG.

Different hydration protocols for the quantification of healthy tissue uptake of half-dose F-FDG total-body positron emission tomography-computed tomography: a prospective study.

Background: This study aimed to investigate the effects of the volume and time of hydration on the quantification of healthy tissue uptake for 2-deoxy-2-[F]-fluoro-D-glucose (F-FDG) total-body positron emission tomography (PET)-computed tomography (CT) with half-dose activity.

Methods: This study prospectively enrolled 180 patients who underwent a total-body PET-CT scan 10 min after injection of a half-dose (1.85 MBq/kg) of F-FDG.

Ultralow-dose [F]FDG PET/CT imaging: demonstration of feasibility in dynamic and static images.

Objectives: Validation of [F]FDG PET/CT at ultralow-dose (0.37 MBq/kg) and compared to imaging at half-dose (1.85 MBq/kg).

A personal acquisition time regimen of Ga-DOTATATE total-body PET/CT in patients with neuroendocrine tumor (NET): a feasibility study.

Background: The injection activity of tracer, acquisition time, patient-specific photon attenuation, and large body mass, can influence on image quality. Fixed acquisition time and body mass related injection activity in clinical practice results in a large difference in image quality. Thus, this study proposes a patient-specific acquisition time regimen of  Ga-DOTATATE total-body positron emission tomography-computed tomography (PET/CT) to counteract the influence of body mass (BM, kg) on image quality, and acquire an acceptable and constant image of patients with neuroendocrine tumors (NETs).

Optimizing acquisition times for total-body positron emission tomography/computed tomography with half-dose F-fluorodeoxyglucose in oncology patients.

Background: The present study aimed to explore the boundary of acquisition time and propose an optimized acquisition time range for total-body positron emission tomography (PET)/computed tomography (CT) oncological imaging using half-dose (1.85 MBq/kg) F-fluorodeoxyglucose activity based on diagnostic needs.

Methods: In this retrospective study based on a total-body PET system (uEXPLORER), an exploration cohort (October 2019-December 2019) of 46 oncology patients was first studied.

Half-dose versus full-dose 18 F-FDG total-body PET/CT in patients with colorectal cancer.

Purpose: The purpose of this study was to investigate image quality and lesion detectability of half-dose (1.85 MBq/kg) 18 F-fluorodeoxyglucose (FDG) total-body positron emission tomography/computed tomography (PET/CT) for colorectal cancer, full-dose (3.7 MBq/kg) 18 F-FDG serving as a reference.

Exploration of the total-body PET/CT reconstruction protocol with ultra-low F-FDG activity over a wide range of patient body mass indices.

Purpose: The purpose of this study was to investigate the image quality and diagnostic performance of different reconstructions over a wide range of patient body mass indices (BMIs) obtained by total-body PET/CT with ultra-low F-FDG activity (0.37 MBq/kg).

Methods: A total of 63 patients who underwent total-body PET/CT with ultra-low activity (0.

Investigating ultra-low-dose total-body [18F]-FDG PET/CT in colorectal cancer: initial experience.

Purpose: This study was to evaluate the effects of an ultra-low dose of [18F]-FDG on the image quality of total-body PET/CT and its lesion detectability in colorectal cancer (CRC).

Methods: Sixty-two CRC patients who underwent total-body PET/CT (uEXPLORER, United Imaging Healthcare, Shanghai, China) with an ultra-low dose (0.37 MBq/kg) of [18F]-FDG were enrolled in this retrospective study.

Can the BMI-based dose regimen be used to reduce injection activity and to obtain a constant image quality in oncological patients by F-FDG total-body PET/CT imaging?

Purpose: PET image quality is influenced by the patient size according to the current guideline. The study aimed to propose an optimized dose regimen to yield a constant image quality independent of patient habitus to meet the clinical needs.

Methods: A first patient cohort of 78 consecutive oncological patients (59.

Surface Acoustic Wave DMMP Gas Sensor with a Porous Graphene/PVDF Molecularly Imprinted Sensing Membrane.

In this paper, surface acoustic wave (SAW) sensors containing porous graphene/PVDF (polyvinylidene fluoride) molecularly imprinted sensitive membrane for DMMP gas detection were investigated. A 433 MHz ST-cut quartz SAW resonator was used to convert gas concentration changes into frequency shifts by the sensors. The porous graphene/PVDF film was fabricated on the sensor's surface by using the tape-casting method.

Total-body PET/CT using half-dose FDG and compared with conventional PET/CT using full-dose FDG in lung cancer.

Purpose: The purpose was to explore the effects of total-body PET/CT with half-dose F-FDG activity on image quality, compared with those of conventional PET/CT with clinical routine full-dose F-FDG in lung cancer.

Methods: Fifty-six primary lung cancer patients who underwent total-body PET/CT on a uEXPLORER scanner with half-dose (1.85 MBq/kg) F-FDG activity before treatment were retrospectively studied; among them, 28 patients were confirmed by postoperative pathologic examination and 28 patients by biopsy.

Total-Body PET/Computed Tomography Highlights in Clinical Practice: Experiences from Zhongshan Hospital, Fudan University.

"The initial experience of using total-body PET/computed tomography (CT) (uExplorer) in Zhongshan Hospital, Fudan University, is described. Compared with conventional PET/CT, total-body PET/CT imaging provides more comprehensive information for evaluation of disease. Using fludeoxyglucose F 18, regular-dose (3.

Elevated 18F-FDG Uptake in Skeletal Muscles Rather Than Cutaneous Foci in a Patient With Sweet's Syndrome.

A 64-year-old man was admitted to our hospital with a history of recurrent fever lasting 2 months. The initial physical examination for the patient showed normal cutaneous signs. An elevated uptake of tracer in skeletal muscles was observed by F-FDG PET/CT imaging.

Sampling survey of disability in 0-6 year-old children in China.

Objective: To investigate the current status of disabled children and prevalence of disabilities in children aged 0-6 years and their risk factors, and to provide scientific evidence for making relevant policies for disabled children.

Methods: In a community-based cross-sectional study, multi-phase, stratified, unequal proportional and cluster sampling was adopted to survey 60 124 children aged 0-6 years. All the investigated children were screened for disabilities, and those with positive screening tests were further diagnosed by various specialties.