Analysis of the effect of calcium ions on promoting the penetrability of riboflavin into the corneal stroma by iontophoresis.

Purpose: To investigate the effect of calcium ions on promoting the penetrability of riboflavin into the corneal stroma by iontophoresis and to analyse the possible mechanism.

Methods: Forty rabbits were divided into five groups randomly: 0.1% riboflavin-balanced salt solution (BSS) by iontophoresis group, 0.

Identification and Quantification of Organic Contaminants and Evaluation of Their Effects on Amine Foaming in the Natural Gas Sweetening Industry.

Contamination is a leading cause of corrosion, foaming, and amine-absorption capacity limitation, predominantly foaming. There is currently an urgent need to identify the sources of amine foaming and eliminate them or reduce their impacts. Gas chromatography-mass spectrometry (GC-MS) and a sample pretreatment method were developed to identify and quantify the organic contaminants.

Changes of matrix metalloproteinases in the stroma after corneal cross-linking in rabbits.

Aim: To observe changes in the content of matrix metalloproteinases (MMPs) in the corneal stroma after corneal cross-linking (CXL) in rabbits, and further explore the corneal pathophysiological process after CXL.

Methods: Forty-two rabbits (42 eyes) were randomly divided into seven groups. One group served as the control group, while the other six groups were treated with CXL.

Young patients with divergence insufficiency related to excessive near work.

The purpose of this study is to explore the relationships between excessive near work and divergence insufficiency esotropia in young adults. A prospective study described a series of young patients with divergence insufficiency esotropia related to excessive near work between 2012 and 2017. The medical records of twelve young patients with divergence insufficiency esotropia and a history of excessive near work were reviewed, and the duration of near work, angle of primary position deviations at distance and at near, and angle of primary position deviations after refraining from near work for 3 months were analyzed.

The Risk of Retinopathy of Prematurity in the Infants following Assisted Reproductive Technology: A Meta-Analysis.

Currently, the use of assisted reproductive technology (ART) is increasing. Because of the poor prognosis of retinopathy of prematurity (ROP), the association between ART and the ROP has been explored in several studies, but the result was still inconclusive. Conducting a meta-analysis, we evaluated the risk of ROP in relation to the ART.

Intravitreal dexamethasone implants versus intravitreal anti-VEGF treatment in treating patients with retinal vein occlusion: a meta-analysis.

Background: Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implants and anti-vascular endothelial growth factor (VEGF).

Efficacy of iontophoresis-assisted epithelium-on corneal cross-linking for keratoconus.

Corneal cross-linking (CXL) is a noninvasive therapeutic procedure for keratoconus that is aimed at improving corneal biomechanical properties by induction of covalent cross-links between stromal proteins. It is accomplished by ultraviolet A (UVA) radiation of the cornea, which is first saturated with photosensitizing riboflavin. It has been shown that standard epithelium-off CXL (S-CXL) is efficacious, and it has been recommended as the standard of care procedure for keratoconus.

Iontophoresis-assisted corneal crosslinking using 0.1% riboflavin for progressive keratoconus.

Aim: To report the clinical results of iontophoresis-assisted epithelium-on corneal crosslinking (I-CXL) using 0.1% riboflavin in distilled water for progressive keratoconus.

Methods: In this prospective clinical study, we examined 94 eyes of 75 patients with progressive keratoconus who were treated with I-CXL using 0.

Riboflavin concentration in corneal stroma after intracameral injection.

Aim: To evaluate the enrichment of riboflavin in the corneal stroma after intracameral injection to research the barrier ability of the corneal endothelium to riboflavin in vivo.

Methods: The right eyes of 30 New Zealand white rabbits were divided into three groups. Different concentrations riboflavin-balanced salt solutions (BSS) were injected into the anterior chamber (10 with 0.

Clinical observation of transepithelial corneal collagen cross-linking by lontophoresis of riboflavin in treatment of keratoconus.

Purpose: To evaluate the efficacy and safety of transepithelial collagen cross-linking by iontophoretic delivery of riboflavin in treatment of progressive keratoconus.

Methods: Eleven patients (15 eyes) with progressive keratoconus were enrolled. After 0.

Research progress in corneal cross-linking agents.

Corneal collagen cross-linking with UVA-riboflavin is currently the only method for preventing the progression of keratoconus from the pathological perspective. Topical application of a direct cross-linking agent is now attracting widespread attention in clinical settings. This article reviews the research progress in the application of indirect or direct cross-linking agents (e.

Corneal collagen cross-linking in keratoconus: a systematic review and meta-analysis.

The aim of this study was to determine the effectiveness of corneal collagen cross-linking (CXL) for the treatment of progressive keratoconus (KC). Some of the published literature, including a few small, randomized controlled trials (RCTs), demonstrated good results after CXL, but large RCTs with long-term follow-up to establish a cause-effect relationship are lacking. Using PubMed, EMBASE, and the Cochrane Library database, we searched for relevant studies published between October 2007 and March 2014.

Variation in central corneal thickness during open- or closed-eye riboflavin instillation for corneal collagen cross-linking.

Purpose: To assess the effect of having an open or closed eye on the variation in central corneal thickness during riboflavin instillation for corneal collagen cross-linking (CXL).

Methods: Thirty eyes of 15 New Zealand White rabbits underwent an in vivo anterior segment optical coherence tomography (OCT) examination at 0, 10, 20, and 30 min after riboflavin instillation on the de-epithelialized corneal surface. Each eye of every rabbit was randomly placed into one of two different treatment groups (open-eye or closed-eye) during the instillation; the examinations were performed one after the other.

In vivo implantation of hydrophobic acrylic intraocular lenses with surface modification.

Purpose: To assess the surface properties of modified hydrophobic acrylic intraocular lenses (IOL) implanted in rabbits.

Methods: The hydrophobic acrylic IOLs were modified with monomer vinyl pyrrolidone by surface modification technique. Phacoemulsification combined with IOL implantation was conducted in 9 rabbits (18 eyes).

Corneal refractive surgery and phakic intraocular lens for treatment of amblyopia caused by high myopia or anisometropia in children.

Objective: A systematic review of literature was performed to compare various visual function parameters including the final visual acuity outcome and/or adverse events between corneal refractive surgery (CLRS) and phakic intraocular lens implantation (p-IOLi) in the treatment of refractive amblyopic children.

Data Sources: Two reviewers independently searched the PubMed, EMBASE, and Controlled Trials Register databases for publications from 1991 to 2013.

Study Selection: There were 25 articles, including 597 patients and 682 eyes, was included in CLRS group.

New techniques to improve classical corneal collagen cross-linking treatment.

Objective: The aim of this review is to comprehensively and unbiasedly summarize the improvements in the techniques for classical corneal collagen cross-linking (CXL) by covering the reasons for this improvement, measure, and effect to approach the future direction of the CXL.

Data Sources: All articles used in this review were mainly retrieved from the PubMed database.

Study Selection: Original articles and reviews were selected if they were related to the improvement in the technique of classical CXL.

Progress of corneal collagen cross-linking combined with refractive surgery.

As a photochemical reaction that can stiffen the cornea, corneal collagen cross-linking (CXL) is the only promising method of preventing the progress of keratectasia, such as keratoconus and secondary ectasia following refractive surgery. The aim of CXL is to stabilize the underlying condition, with a small chance of visual improvement. Combining CXL with refractive surgery targeting both stabilization and reshaping of the corneal tissue for visual function improvement is a good treatment option.

Iontophoretic delivery of riboflavin into the rabbit cornea: a primary study.

Purpose: To determine the penetrability of riboflavin into the corneal stroma by iontophoresis and to compare the permeability effects of different solvents.

Methods: Twenty rabbits were randomly divided into four groups: a group that received 0.1% riboflavin-balanced salt solution (BSS) by iontophoresis, a group that received 0.

[Corneal collagen cross-linking in the treatment of progressive keratoconus-preliminary results].

Objective: To evaluate the efficacy and safety of riboflavin-ultraviolet-A (UV-A)-induced corneal collagen cross-linking (CXL) in the management of progressive keratoconus.

Methods: It was a retrospective case series study. Twenty-three eyes of 13 patients with progressive keratoconus were included.

Comparison of central corneal thickness using ultrasound pachymetry during corneal collagen cross-linking.

Purpose: To study variation in central corneal thickness (CCT) during corneal collagen cross-linking(CXL) using ultrasound pachymetry.

Methods: Twenty patients (26 eyes) with progressing keratoconus undergoing riboflavin-UVA-induced CXL were involved in this study. Intraoperative CCT measurement using ultrasonic pachymetry was performed during the procedure.

Corneal collagen fibril changes after ultraviolet a/riboflavin corneal crosslinking.

Purpose: The aim was to investigate the changes in collagen type 1 and type 3 in rabbit corneas undergoing corneal crosslinking with ultraviolet A and riboflavin and to analyze the possible mechanisms of corneal haze formation.

Methods: After removal of the central epithelium, the right corneas of 60 New Zealand rabbits were crosslinked with riboflavin and ultraviolet A, and 10 additional rabbits were used as the control group. The animals were killed 3, 7, 15, 30, 90, and 180 days postoperatively.

Corneal collagen crosslinking for corneal ectasia of post-LASIK: one-year results.

Aim: To evaluate the efficacy and safety of corneal collagen crosslinking (CXL) to prevent the progression of post-laser in situ keratomileusis (LASIK) corneal ectasia.

Methods: In a prospective, nonrandomized, single-centre study, CXL was performed in 20 eyes of 11 patients who had LASIK for myopic astigmatism and subsequently developed keratectasia.The procedure included instillation of 0.

Study on the surface properties of surface modified silicone intraocular lenses.

Aim: To prepare a new-type soft intraocular lens (IOL) that silicone intraocular lenses (IOLs) were modified by surface modification technique to assess IOLs biocompatibility.

Methods: With the technique of ion beam combined with low temperature and low pressure plasma, the surface characteristics of the IOLs including physical and optical properties were determined by the instruments of IOLs resolution, UV/VIS scanning spectrophotometer, contact angle measurement system, electron spectroscopy for chemical analysis (ESCA) and scanning electron microscope (SEM).

Results: The color of titanium (Ti) modified IOLs was light yellow and that of titanium nitride (TiN) modified IOLs was light brown.

Retinitis pigmentosa patients' attitudes toward participation in retinal prosthesis trials.

Purpose: We undertook a questionnaire study to explore the retinitis pigmentosa (RP) patients' attitudes and the main reasons for or against participation in retinal prosthesis trials.

Methods: Fifty-four patients, who might be potential participants of retinal prosthesis trials, were recruited to complete the questionnaire devised to determine RP patients' willingness, motivations and expectations toward participation in retinal prosthesis trials, identify the concerns of RP patients about participation in retinal prosthesis trials.

Results: Eleven (11/54[21%]) of fifty-four patients were willing to participate in retinal prosthesis trials.