Publications by authors named "Xiujun Mai"
Rationale: Less-Invasive Stabilization System (LISS) plate is an internal fixation commonly used for the periprosthetic distal femur fractures. Failure associated with LISS plate has been rarely reported, and the reasons for LISS plate failure are multitudinous. Various advantages have been reported, but failures continue.
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- A study compared unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO) for treating unicompartmental knee osteoarthritis, focusing on postoperative outcomes like revision rates, complications, function, range of motion (ROM), and pain.
- The meta-analysis included 10 studies, revealing that UKA patients had lower revision rates, fewer complications, and less postoperative pain compared to HTO patients, who enjoyed better range of motion.
- Ultimately, UKA is deemed a safe option with less pain and complications, while HTO may be better for more active patients due to its superior ROM; each patient's treatment should be tailored based on individual factors like age and activity level.
Background: TAR DNA-binding protein-43 (TDP-43, transactive response DNA binding protein 43kDa) accumulates in the cytoplasm of affected neurons and glia, as large inclusions of stress granules (SGs). However, the mechanism of TDP-43 interaction with the target genes and its specific role in osteoarthritis (OA) progression is still unknown. The goal of this study was to identify the role of TDP-43 in OA progression by modulating its target genes.
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