Publications by authors named "Xiujuan Yuan"

The coadsorption of anionic and cationic pollutants on adsorbents holds considerable importance in the development of relevant removal technologies and the understanding of pollutant transport in complex environmental media. Herein, tungsten (W), an emerging contaminant, and nickel (Ni) were chosen as two differently charged inorganic pollutants to investigate their removal characteristics on a magnesium-aluminum layered double hydroxide (LDH) prepared via microwave radiation. In the single systems, the amount of adsorbed W on LDH was initially increased and then decreased with increasing initial W concentration.

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The coexistence of highly toxic chromium (Cr) and the emerging contaminant tungsten (W) in the soil adjacent to W mining areas is identified. Immobilization of W and/or Cr is vital for the safe utilization of contaminated soil. In this study, the cationic gemini surfactant (butane-1,4-bis(dodecyl dimethyl ammonium bromide)) and tetrachloroferrate (FeCl)-modified montmorillonite (FeOMt) was applied to investigate the retention performance of W and/or Cr in the soil.

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Alkyl quaternary ammonium-modified clay minerals, which are common environmentally friendly materials, have been widely studied and applied for the removal of pollutants. However, there are few reports on functionalizing the counterions to expand the application. In this study, the cationic gemini surfactant butane-1,4-bis(dodecyl dimethyl ammonium bromide) (gBDDA) and tetrachloroferrate (FeCl) are designed to modify montmorillonite (Mt), and the obtained FeCl/Gemini-Mt composite (FeOMt) is used for the removal of nitrate and/or phosphate from aqueous solution.

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The ERK pathway is critical in oncogenesis; aberrations in components of this pathway are common in approximately 30% of human cancers. ERK1/2 (ERK) regulates cell proliferation, differentiation, and survival and is the terminal node of the pathway. BRAF- and MEK-targeted therapies are effective in BRAF V600E/K metastatic melanoma and lung cancers; however, responses are short-lived due to emergence of resistance.

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Bacillus cereus not only has adverse effects on the nutrition and shelf life of dairy products but also seriously endanger people's health. This study was conducted to reveal the prevalence and genetic diversity of B. cereus strains isolated from raw milk and cattle farm environments.

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Cronobacter species (formerly Enterobacter sakazakii) are emerging opportunistic bacterial pathogens that can infect both infants and adults. This study was conducted to isolate and genotype diverse Cronobacter species from drinking water, chilled fresh pork, powdered infant formula, instant noodles, cookies, fruits, vegetables, and dishes in Northeast China and to evaluate the antibiotic resistance and susceptibility of the isolates. Thirty-four Cronobacter strains were isolated and identified: 21 C.

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is an opportunistic pathogen that causes severe infections in neonates and infants through contaminated powdered infant formula (PIF). Therefore, the aim of this study was a large-scale study on determine the prevalence, molecular characterization and antibiotic susceptibility of isolates from PIF purchased from Chinese retail markets. Two thousand and twenty PIF samples were collected from different institutions.

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Activating mutations in the KRAS and BRAF genes, leading to hyperactivation of the RAS/RAF/MAPK oncogenic signaling cascade, are common in patients with colorectal cancer (CRC). While selective BRAF inhibitors are efficacious in BRAFmut melanoma, they have limited efficacy in BRAFmut CRC patients. In a RASmut background, selective BRAF inhibitors are contraindicated due to paradoxical activation of the MAPK pathway through potentiation of CRAF kinase activity.

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For the first time, the analytical application of integrate ionophore-transducer material based on magnetic graphene hybrids and 2,2-dithiodipyridine (DTDP) in solid-contact lanthanum (III) selective electrode is reported. The attachment of Fe3O4 nanoparticles (NPs) to graphene oxide (GO) for magnetic graphene hybrid is achieved by covalent bonding, and the universal problem, Fe3O4 NPs may easily leach out from the graphene during application, is successfully solved by the method above. The proposed electrode exhibits an excellent near-Nernstian response to lanthanum (III) ranging from 1.

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Background: CC-family chemokine receptor 2 (CCR2) is implicated in the trafficking of blood-borne monocytes to sites of inflammation and is implicated in the pathogenesis of several inflammatory diseases such as rheumatoid arthritis, multiple sclerosis and atherosclerosis. The major challenge in the development of small molecule chemokine receptor antagonists is the lack of cross-species activity to the receptor in the preclinical species. Rabbit models have been widely used to study the role of various inflammatory molecules in the development of inflammatory processes.

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The ability of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis preferentially in cancer cells is attractive for its development as a novel cancer therapeutic agent, but many cancer cell lines are resistant to TRAIL. While the molecular basis for TRAIL resistance is not always clear, a number of factors have been proposed to mediate TRAIL resistance, including decoy receptor, c-FLIP, nuclear factor (NF)-kappaB, and activation of antiapoptotic kinase signaling. Many growth factor receptors mediate their survival signals through the pathway involving recruitment and activation of phosphatidylinositol (PI) 3-kinase and the serine?threonine kinase Akt.

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Objective: To understand socio-economic losses of inpatients and deaths caused by injuries in 2000 in Ningxia and to estimate their extent of harmfulness.

Methods: Eight of 35 local hospitals totaling 5 876 inpatients were recruited with two-stage sampling in Ningxia in 2000. All medical cost incurred during their hospitalizations for injuries, cardiovascular and cerebrovascular diseases, respiratory disease, cancer and communicable diseases, losses in labor time were analyzed, and years of potential life lost (YPLL), working years of potential lost (WYPLL), valued years of potential life lost (VYPLL) due to these diseases were estimated for the residents in Ningxia with corrected human capital method.

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The PTEN tumor suppressor is frequently mutated in human tumors. Loss of PTEN function is associated with constitutive survival signaling through the phosphatidylinositol-3 kinase/Akt pathway. Therefore, we asked if reconstitution of PTEN function would lead to the reversal of resistance to apoptosis in prostate cancer cells.

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PTEN is a lipid phosphatase responsible for down-regulating the phosphoinositide 3-kinase product phosphatidylinositol 3,4,5-triphosphate. Phosphatidylinositol 3,4,5-triphosphate is involved in the activation of the anti-apoptotic effector target, Akt. Although the Akt pathway has been implicated in regulating NF-kappaB activity, it is controversial as to whether Akt activates NF-kappaB predominantly through mechanisms that regulate nuclear translocation or transactivation potential.

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