High Spin-State Modulation of Catalytic Centers by Weak Ligand Field for Promoting Sulfur Redox Reaction in Lithium-Sulfur Batteries.

The spin state of transition-metal compounds in lithium-sulfur batteries (LSBs) significantly impacts the electronic properties and the kinetics of sulfur redox reactions (SRR). However, accurately designing the spin state remains challenging, which is crucial for understanding the structure-performance relationship and developing high-performance electrocatalysts. Herein, the CoF, specifically the Co with 3d electrons in a high-spin state distribution (t e ), were tailored predictably for the first time through the weak coordination field effect of the F element.

The role of METTL3-mediated CircStk4 modification in the treatment of chronic glomerulonephritis with Qi Teng Xiao Zhuo granule.

Background: Qi Teng Xiao Zhuo granule (QTXZG), a compound preparation used in traditional Chinese medicine, is a highly effective treatment for chronic glomerulonephritis (CGN). Previously, the mechanism of circStk4 and the N-methyladenosine (mA) modification of circStk4 in CGN was elucidated in vivo. Nevertheless, there hasn't been any research done on the connection between circStk4 and QTXZG's mechanism in CGN treatment.

A unique three-dimensional network double-core-shell structure S@MnO@MXene suppresses the shuttle effect in high-sulfur-content high-performance lithium-sulfur batteries.

Lithium-sulfur (Li-S) batteries represent the most promising next-generation energy storage systems because of their high theoretical specific capacity and energy density. However, the severe shuttle effect and volume expansion of sulfur cathodes have impeded their commercial viability. Hence, accelerating the conversion of lithium polysulfides (LiPSs) is crucial for achieving efficient Li-S batteries.

Exploring the mechanism of Corbrin capsules in the intervention of AKI-COVID-19 based on network pharmacology combined with GEO dataset.

Aim: of the study: This study used network pharmacology and the Gene Expression Omnibus (GEO) database to investigate the therapeutic effects of Corbrin capsules on acute kidney injury (AKI)-COVID-19 (coronavirus disease 2019).

Materials And Methods: The active constituents and specific molecular targets of Corbrin capsules were obtained from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) and Swiss Target Prediction databases. The targets related to AKI and COVID-19 disease were obtained from the Online Mendelian Inheritance in Man (OMIM), GeneCards, and GEO databases.

METTL3 modification of circStk4 affects mouse glomerular messangial cell autophagy, proliferation and apotosis by regulating miR-133a-3p/C1 axis.

Objective: The study aimed to explore the impact of N6-methyladenosine (mA) modification in circStk4 on glomerular mesangial cells (GMCs) autophagy, proliferation and apoptosis.

Methods: The interactions between circStk4 and miR-133a-3p, miR-133a-3p and C1 were demonstrated through luciferase reporter assays. The circStk4 localization was analyzed using fluorescence in situ hybridization and nuclear/cytosol fractionation assays.

Real-time 4K computer-generated hologram based on encoding conventional neural network with learned layered phase.

Learning-based computer-generated hologram (CGH) demonstrates great potential for real-time high-quality holographic displays. However, real-time 4K CGH generation for 3D scenes remains a challenge due to the computational burden. Here, a variant conventional neural network (CNN) is presented for CGH encoding with learned layered initial phases for layered CGH generation.

CsBZIP40 confers resistance against citrus bacterial canker by repressing CsWRKY43-CsPrx53/CsSOD13 cascade mediated ROS scavenging.

As the bacterial etiologic agent causing citrus bacterial canker (CBC), subsp. () seriously impacts citrus plantation and fruit production globally. In an earlier study, we demonstrated that CsBZIP40 can positively impact CBC resistance in the sweet orange ().

Identification of Rab7 as an autophagy marker: potential therapeutic approaches and the effect of Qi Teng Xiao Zhuo granule in chronic glomerulonephritis.

Context: Qi Teng Xiao Zhuo granule (QTXZG) is a traditional Chinese medicine (TCM) used for therapeutic effects on chronic glomerulonephritis (CGN). However, the underlying mechanism remains unclear.

Objective: To investigate the molecular mechanism of QTXZG on CGN by proteomics.

Identification of immunosuppressive signature subtypes and prognostic risk signatures in triple-negative breast cancer.

Purpose: Immune checkpoint blockade (ICB) therapy has transformed the treatment of triple-negative breast cancer (TNBC) in recent years. However, some TNBC patients with high programmed death-ligand 1 (PD-L1) expression levels develop immune checkpoint resistance. Hence, there is an urgent need to characterize the immunosuppressive tumor microenvironment and identify biomarkers to construct prognostic models of patient survival outcomes in order to understand biological mechanisms operating within the tumor microenvironment.

Real-Time High-Quality Computer-Generated Hologram Using Complex-Valued Convolutional Neural Network.

Holographic displays are ideal display technologies for virtual and augmented reality because all visual cues are provided. However, real-time high-quality holographic displays are difficult to achieve because the generation of high-quality computer-generated hologram (CGH) is inefficient in existing algorithms. Here, complex-valued convolutional neural network (CCNN) is proposed for phase-only CGH generation.

Multi-Depth Computer-Generated Hologram Based on Stochastic Gradient Descent Algorithm with Weighted Complex Loss Function and Masked Diffraction.

In this paper, we propose a method to generate multi-depth phase-only holograms using stochastic gradient descent (SGD) algorithm with weighted complex loss function and masked multi-layer diffraction. The 3D scene can be represented by a combination of layers in different depths. In the wave propagation procedure of multiple layers in different depths, the complex amplitude of layers in different depths will gradually diffuse and produce occlusion at another layer.

High Resolution Multiview Holographic Display Based on the Holographic Optical Element.

Limited by the low space-bandwidth product of the spatial light modulator (SLM), it is difficult to realize multiview holographic three-dimensional (3D) display. To conquer the problem, a method based on the holographic optical element (HOE), which is regarded as a controlled light element, is proposed in the study. The SLM is employed to upload the synthetic phase-only hologram generated by the angular spectrum diffraction theory.

Binocular holographic display based on the holographic optical element.

Due to the limited pixel pitch of the spatial light modulator (SLM), the field of view (FOV) is insufficient to meet binocular observation needs. Here, an optimized controlling light method of a binocular holographic three-dimensional (3D) display system based on the holographic optical element (HOE) is proposed. The synthetic phase-only hologram uploaded onto the SLM is generated with the layer-based angular spectrum diffraction theory, and two different reference waves are introduced to separate the left view and the right view of the 3D scene.

Real-time realistic computer-generated hologram with accurate depth precision and a large depth range.

Holographic display is an ideal technology for near-eye display to realize virtual and augmented reality applications, because it can provide all depth perception cues. However, depth performance is sacrificed by exiting computer-generated hologram (CGH) methods for real-time calculation. In this paper, volume representation and improved ray tracing algorithm are proposed for real-time CGH generation with enhanced depth performance.

High-throughput data on circular RNA reveal novel insights into chronic glomerulonephritis.

Background: Circular RNAs (circRNAs), a unique novel type of RNA, have been widely reported to be involved in physiologic and pathologic processes in humans. However, the exact molecular pathogenesis of circRNAs in chronic glomerulonephritis (CGN) is far from clear.

Objective: This paper aims to evaluate the specific expression profile of circRNAs in renal cortex tissues from Adriamycin-induced CGN rats.

Spectroscopic Monitoring of the Electrode Process of MnO@rGO Nanospheres and Its Application in High-Performance Flexible Micro-Supercapacitors.

Structural instability is a major obstacle to realizing the high performance of a MnO-based pseudocapacitor material. Understanding its structure transformation in the process of electrochemical reaction, therefore, plays an important role in the efficient enhancement of rate capacity and stability. Herein, a stable MnO@rGO core-shell nanosphere is first synthesized by a liquid-liquid interface deposition further combined with the electrostatic self-assembly method.

Long Non-Coding NONRATG001910.2 Promotes the Proliferation of Rat Mesangial Cell Line HBZY-1 Through the miR-339-3p/CTNNB1 Axis.

Chronic glomerulonephritis (CGN) is one of the leading causes of end-stage renal disease (ESRD). A growing body of literature emphasizes the important role of long non-coding RNAs (lncRNAs) in the development and progression of the disease. However, the function of NONRATG001910.

Electrodeposited Co-W-P ternary catalyst for hydrogen evolution reaction.

In order to reduce the overpotential of hydrogen evolution reaction (HER), the ternary coating Co-W-P was deposited on the surface of the nickel foam by electrochemical deposition to obtain a highly active electrode. Based on the measured double layer capacitance () and HER activity, there is volcanic behavior between the intrinsic activity of Co-W-P and the Co:W ratio in the electrolyte. W and P play different roles in the formation of nanoparticles, and work together to achieve the large electrochemical surface area and excellent activity.

Stabilized Cathode Interphase for Enhancing Electrochemical Performance of LiNiMnO-Based Lithium-Ion Battery via -1,2,3,6-Tetrahydrophthalic Anhydride.

The continuous degradation of carbonate electrolytes and the dissolution of transition metal cations due to parasitic reactions on the cathode-electrolyte interphase (CEI) block the practical application of LiNiMnO-based lithium-ion batteries (LNMO-based LIBs) at a high voltage. -1,2,3,6-Tetrahydrophthalic anhydride (CTA) has been used as a functional additive in a carbonate baseline electrolyte (BE) for constructing the CEI film to enhance the cyclic stability of LNMO-based LIBs. The LNMO/Li cell with CTA exhibits a preponderant capacity retention of 83.

CsPrx25, a class III peroxidase in Citrus sinensis, confers resistance to citrus bacterial canker through the maintenance of ROS homeostasis and cell wall lignification.

Citrus bacterial canker (CBC) results from Xanthomonas citri subsp. citri (Xcc) infection and poses a grave threat to citrus production. Class III peroxidases (CIII Prxs) are key proteins to the environmental adaptation of citrus plants to a range of exogenous pathogens, but the role of CIII Prxs during plant resistance to CBC is poorly defined.

Systematic Analysis and Functional Validation of Citrus Pectin Acetylesterases (CsPAEs) Reveals that CsPAE2 Negatively Regulates Citrus Bacterial Canker Development.

The present study was designed to serve as a comprehensive analysis of () pectin acetylesterases (CsPAEs), and to assess the roles of these PAEs involved in the development of citrus bacterial canker (CBC) caused by subsp. () infection. A total of six were identified in the genome of , with these genes being unevenly distributed across chromosomes 3, 6, and 9, and the unassembled scaffolds.

[miR-324-5p inhibits lipopolysaccharide-induced proliferation of rat glomerular mesangial cells by regulating the Syk/Ras/c-fos pathway].

Objective: To investigate the effect of miR-324-5p on the proliferation of rat glomerular mesangial (HBZY-1) cells and the role of Syk/Ras/c-fos signaling pathway in mediating this effect.

Methods: HBZY-1 cells cultured in vitro were transiently transfected with miR-324-5p mimics or miR-324-5p-mimics-NC followed by treatment with lipopolysaccharide (LPS). MTT assay was used to detect the proliferation activity of HBZY-1 cells, and RT-qPCR was used to detect the expressions of miR-324-5p and the mRNA expressions of Syk, Ras, MEK1/2, ERK1/2 and c-fos mRNA.

Stable Electrochemical Li Plating/Stripping Behavior by Anchoring MXene Layers on Three-Dimensional Conductive Skeletons.

The ultrahigh specific capacity of lithium (Li) metal makes it possible to serve as the ultimate candidate for an anode in high-energy density secondary batteries, whereas the safety hazards caused by Li dendrite growth severely hamper the commercialization process of a lithium metal anode. Here, we propose a 3D conductive skeleton by anchoring MXene on Cu foam (MXene@CF) to significantly improve the electrochemical Li plating/stripping behavior. Li metal tends to nucleate uniformly and grow horizontally along the MXene nanosheets under the strong Coulomb interaction between adsorbed Li and MXene.

Core-Shell-Structured Sulfur Cathode: Ultrathin δ-MnO Nanosheets as the Catalytic Conversion Shell for Lithium Polysulfides in High Sulfur Content Lithium-Sulfur Batteries.

Owing to their low cost and high theoretical energy density, lithium-sulfur (Li-S) batteries are highly promising as a contender for the post-lithium-ion battery era. However, the intrinsic low reversible conversion ability of lithium polysulfides to sulfur/LiS during charging/discharging seriously hinders the sulfur utilization, resulting in poor cycling life of batteries. Herein, we report an improvement of core-shell-structured sulfur nanospheres@ultrathin δ-MnO nanosheet electrode materials prepared by a simple precipitation reaction method, in which the ultrathin δ-MnO nanosheets as a catalytic layer can promote the chemical adsorption of lithium polysulfides and their conversion rates to sulfur/LS.