Publications by authors named "Xiuji Du"
DNA hydrogel represents a potent material for crafting biological scaffolds, but the toolbox to systematically regulate the mechanical property is still limited. Herein, we have provided a strategy to tune the stiffness of DNA hydrogel through manipulating the rigidity of DNA modules. By introducing building blocks with higher molecular rigidity and proper connecting fashion, DNA hydrogel stiffness could be systematically elevated.
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- The extracellular matrix (ECM) significantly influences cell behavior, especially during tissue development and wound healing due to its changing mechanical strength.
- A new strategy for creating hydrogels with gradually increasing mechanical strength is introduced, allowing them to retain properties like self-healing and shear-thinning.
- This approach enables researchers to investigate how the gradual stiffening of ECM affects cell behavior over time.