Strain-Compensated Quantum Well Asymmetric Waveguide Edge-Emitting Laser Operating at 730 nm.

Semiconductor lasers operating at the 730 nm peak wavelength have diverse applications, including biomedical diagnostics, agricultural lighting, and high-precision sensing. However, quantum well (QW) materials, commonly employed at this wavelength, often fail to simultaneously meet the dual requirements of lattice matching and bandgap alignment. In this study, GaAsP/AlGaInP large strain compensation QW with lattice mismatches of -7.

AI-Assisted Passive Magnetic Distance/Position Sensor.

Magnetic sensing technology is crucial for non-contact distance and position measurement. Due to the nonlinear characteristics of the magnetic fields from permanent magnets, conventional magnetic sensors struggle with accurate distance and position determination. To address this, we propose a distance/position sensor that employs a customized back propagation (BP) neural network.

Robotic Fast Patch Clamp in Brain Slices Based on Stepwise Micropipette Navigation and Gigaseal Formation Control.

The patch clamp technique has become the gold standard for neuron electrophysiology research in brain science. Brain slices have been widely utilized as the targets of the patch clamp technique due to their higher optical transparency compared to a live brain and their intercellular connectivity in comparison to cultured single neurons. However, the narrow working space, small scope, and depth of the field of view make the positioning of the operation's micropipette to the target neuron a time-consuming task reliant on a high level of experience, significantly slowing down operation of the patch clamp technique in brain slices.

Anion-Exchange Strategy for Ru/RuO-Embedded N/S--Doped Porous Carbon Composites for Electrochemical Nitrogen Fixation.

Ionic porous polymers have been widely utilized efficiently to anchor various metal atoms for the preparation of metal-embedded heteroatom-doped porous carbon composites as the active materials for electrocatalytic applications. However, the rational design of the heteroatom and metal elements in HPC-based composites remains a significant challenge, due to the tendency of the aggregation of metal nanoparticles during pyrolysis. In this study, a nitrogen (N)- and sulfur (S)-enriched ionic covalent organic framework (COF) incorporating viologen and thieno[3,4-b] thiophene (TbT) was constructed via Zincke-type polycondensation.

Novel Biobased Double Crystalline Poly(butylene succinate)--poly(butylene 2,5-thiophenedicarboxylate) Multiblock Copolymers with Excellent Thermal and Mechanical Properties and Enhanced Crystallization Behavior.

Novel biobased double crystalline poly(butylene succinate)--poly(butylene 2,5-thiophenedicarboxylate) (PBS--PBTh) multiblock copolyesters with excellent thermal and mechanical properties were prepared from two hydroxyl-terminated PBS-diol and PBTh-diol prepolymers via a chain extension reaction. Both PBS and PBTh segments were semicrystalline, with the aliphatic PBS segment being the soft segment while the aromatic PBTh segment was the hard segment. In the case of PBS--PBTh, the two segments were partially miscible in the amorphous region; moreover, the melting temperature of each segment still remained very high compared with that of each homopolyester PBS and PBTh.

Evaluation of the Immunogenicity of a Pool of Recombinant Expressing Eight Antigens of African Swine Fever Virus in a Mouse Model.

African swine fever (ASF), caused by African swine fever virus (ASFV), poses a great threat to the global pig industry. There is an urgent demand for effective and safe vaccines to address this threat. This study reports the generation and evaluation of a recombinant pool, each strain expressing one of eight ASFV antigens (F317L, H171R, D117L, E120R, B602L, CD2v, p54, and p72).

Gut Barrier Dysfunction and Microbiota Variations in Cryptosporidiosis: A Comprehensive Review.

Cryptosporidiosis is a zoonotic protozoan parasite-born disease, equally significant in both animals and humans, especially affecting immunocompromised individuals (e.g., AIDS patients) and neonates.

Comparison of Soil Microbial Composition in Rhizospheres Between Wilt Disease-Resistant and Susceptible Melon Varieties.

To screen out the bio-control soil microorganisms for preventing melon wilt, soil microbial compositions in rhizospheres between wilt-resistant and susceptible melon varieties were analyzed. The results showed that the soil fungal richness in rhizospheres of wilt-resistant melon varieties (MT) was significantly higher than that of wilt-susceptible melon varieties (MS). Additionally, in comparison with MS, soil bacterial compositions, such as Proteobacteria, Bacteroidota, , etc.

First Report and Pathogenicity Analysis of subsp. in Cage-Cultured Black Rockfish () Associated with Skin Ulcers.

subsp. (PDP), a marine bacterium, has been reported to infect a variety of economically important marine species worldwide. Understanding the occurrence and pathogenicity of PDP is crucial for effective disease control and ensuring the success of aquaculture operations.

Fatal Toxoplasmosis in Red Kangaroos () in East China.

Background: As a ubiquitous apicomplexan parasite, causes huge economic losses and poses a great threat to the health of animals, including humans, worldwide. In some kangaroo species, can be fatal. To date, little information is available on infection in the red kangaroos in east China.

Isolation, Identification, and Molecular Genetic Characteristics of a Pathogenic Strain of Serotype 3.

() is considered as one of the most crucial bacterial pathogens that leads to serious economic losses to the swine industry. Different serotypes exhibit diverse characteristics in population structure and pathogenicity. Epidemiology data underscore the importance of serotype 3 (SS3).

Theoretical Investigation of Competitive Adsorption of Light and Heavy Rare Earth Ions on the (001) Surface of Kaolinite.

Kaolinite is the primary mineral in ion-adsorption rare earth ores, and improving our understanding of the adsorption state of REEs on kaolinite will benefit efforts to leach REEs from these ores. In order to explain why Eu ions exhibit stronger pH-dependent desorption behavior than Lu, molecular dynamics simulations were applied to investigate the adsorption mechanism of Eu and Lu on a deprotonated kaolinite (001) surface. The simulation results show that the hydration numbers of Eu and Lu are comparable, whereas the ordering degree of water molecules around Eu is higher than that of Lu, which is beneficial to the movement of Eu to preferentially occupy favorable adsorption sites on the kaolinite surface, following which coordination bonds are formed between Eu and the surface.

Transcriptomic Characterization of miRNAs in Larvae Responding to Infection.

is a fungal pathogen that specifically infects bee larvae, causing an outbreak of chalkbrood disease in the bee colony and a decline in the number of bee colonies. The role of miRNA regulation in honeybees in response to infection is unclear. In this study, based on small RNA-seq, we identified the differentially expressed miRNAs (DEmiRNAs) and their regulatory networks and functions in the gut of on the first day (AcT1), the second day (AcT2) and the third day (AcT3) after infection, and analyzed the immune response mechanism of through the miRNAs-mRNA regulation network of infection.

Measuring the Effective Electro-Optic Coefficient of Low-Temperature-Prepared Lead Zirconate Titanate Thin Films.

Developing lead zirconate titanate (PZT)-based electro-optic (EO) modulators is vital for integrated photonics. The high annealing temperature required for the processing of PZT thin films restricts their compatibility with modern complementary metal-oxide-semiconductor (CMOS) technology. In this work, high-quality PZT films were fabricated on SiO/Si substrates at a low annealing temperature of 450 °C.

Effect of Bayer Red Mud on the Mechanical Strength of Grouting Material.

The massive stockpiles of Bayer-process red mud (BRM) severely compromise soil integrity, necessitating the urgent development of efficient large-scale utilization strategies. BRM contains large amounts of calcium, silicon, and aluminum. Theoretically, water glass and flue gas desulfurization gypsum (FGD) can increase the active substances in BRM, making it a cementitious raw material capable of replacing cement.

A Starch Phosphorylase, ZmPHOH, Improves Photosynthetic Recovery from Short-Term Cold Exposure in Maize.

The photosynthetic system of maize () leaves is sensitive to low temperatures and suffers from irreversible damage induced by cold exposure, making cold stress a major factor limiting maize yield. Identifying genes that improve the recovery of photosynthesis from low temperatures in maize will help enhance the cold tolerance of this crop and ensure stable yields. Here, we demonstrate the role of () in promoting photosynthetic recovery from cold damage.

Decreasing β-Catenin Leads to Altered Endothelial Morphology, Increased Barrier Permeability and Cognitive Impairment During Chronic Methamphetamine Exposure.

Cognitive impairment induced by chronic methamphetamine (METH) exposure exhibits similarities to neurodegenerative disorders and is associated with blood-brain barrier (BBB) dysfunction. However, the potential involvement of β-catenin in maintaining BBB integrity during METH exposure remains unexplored. In this study, Y-maze and novel object recognition tests were conducted to assess cognitive impairment in mice exposed chronically to methamphetamine for 2 and 4 weeks.

The Effect of on Cadmium Uptake and Gene Expression in Rice.

The molecular mechanism of arbuscular mycorrhizal fungi (AMF) in reducing cadmium (Cd) accumulation in plants remains unclear. In this respect, the effects of (Ri) inoculation under Cd stress on rice growth, the uptake of Cd along with other elements, and the expression of Cd transport genes, including , were studied using wild-type (WT) and mutant rice. The results showed that Ri inoculation did not affect rice growth.

Improved CNN Prediction Based Reversible Data Hiding for Images.

This paper proposes a reversible data hiding (RDH) scheme for images with an improved convolutional neural network (CNN) predictor (ICNNP) that consists of three modules for feature extraction, pixel prediction, and complexity prediction, respectively. Due to predicting the complexity of each pixel with the ICNNP during the embedding process, the proposed scheme can achieve superior performance compared to a CNNP-based scheme. Specifically, an input image is first split into two sub-images, i.

Serum Carnosinase 1 Is Not Associated with Insulin Resistance or Glucose Metabolism in a Type 1 Diabetes Cohort.

: Preclinical studies suggest that the deleterious effect of a high serum carnosinase 1 (CN1) concentration is attributed to its adverse effects on insulin sensitivity and glucose metabolism. However, there is little evidence for a modulating role of CN1 in glucose metabolism in humans. : We measured serum CN1 concentration in an observational type 1 diabetes cohort of 172 patients in whom glucose variability (MAGE, MODD, SD of individual blood glucose, mean, and CV) was recorded by blinded continuous glucose monitoring for 5-7 days.

Integrated Transcriptome and Proteome Analysis Provides New Insights into Starch and Sucrose Metabolism and Regulation of Corm Expansion Process in .

Unlabelled: The global significance of , a tuber crop rich in nutritional value and starch, prompts further investigation into its corm development.

Background: Previous studies have focused on starch accumulation within the tubers, yet the genetic and proteomic basis of corm expansion remains largely unexplored. This study aims to elucidate the key genes and proteins involved in this process.

Stroke-Homing Peptide-DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps.

Neutrophil extracellular traps (NETs) act as a vital first line of defence against tissue damage and pathogens, playing a significant role in improving diseases such as intestinal ischemia reperfusion injury (IRI). However, we observed that after intestinal injury, intestinal bacteria and lipopolysaccharides (LPS) can enter the circulatory system, leading to a significant secondary increase in NETs production and the subsequent activation of a coagulation cascade. This phenomenon contributes to a pathological process known as the 'second strike' of NETs, which exaggerates intestinal damage and microcirculation disturbance.

Post-marketing safety surveillance of Amivantamab: a real world study based on the FDA adverse event reporting system.

Background: Amivantamab stands as the pioneering bispecific antibody that targets both EGFR and MET, utilized in the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EGFR ex20ins mutations. Nevertheless, a thorough assessment of its safety characteristics in the real-world remains unknown.

Research Design And Methods: The adverse event (AE) reports were collected through a search of the FDA Adverse Event Reporting System (FAERS) database spanning from 2019 Q1 to 2024 Q1, and then disproportionality analysis was utilized.

Altered synaptic homeostasis: a key factor in the pathophysiology of depression.

Depression, a widespread psychiatric disorder, is characterized by a diverse array of symptoms such as melancholic mood and anhedonia, imposing a significant burden on both society and individuals. Despite extensive research into the neurobiological foundations of depression, a complete understanding of its complex mechanisms is yet to be attained, and targeted therapeutic interventions remain under development. Synaptic homeostasis, a compensatory feedback mechanism, involves neurons adjusting synaptic strength by regulating pre- or postsynaptic processes.