Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region.

To understand the colonization status of Group B Streptococcus (GBS) in the reproductive tract of pregnant women in the Linyi region, the drug resistance, genotype distribution, and molecular epidemiological characteristics of GBS, and to explore the high-risk factors for GBS infection in late-stage pregnant women. A total of 3269 pregnant women at 35-37 weeks of gestation who visited the Obstetrics Department of Linyi Maternal and Child Health Hospital from January 2019 to December 2021 were selected as the study subjects. Vaginal and rectal swabs were collected for GBS culture.

Preparation and Foam Stabilization Mechanism of an Ultrahigh-Temperature Colloidal Gas Aphron (CGA) System Based on Nano-SiO.

Recently, colloidal gas aphron (CGA) drilling fluids have successfully solved the problem of drilling low-pressure depleted oil and gas reservoirs. However, with the increase in the drilling depth and the development of geothermal resources, high-temperature stable CGA drilling fluids need to be developed urgently. This research reports a highly stable nano-SiO-based CGA system with a temperature resistance of 200 °C.

Lysine Deprivation Suppresses Adipogenesis in 3T3-L1 Cells: A Transcriptome Analysis.

Growing evidence proves that amino acid restriction can reverse obesity by reducing adipose tissue mass. Amino acids are not only the building blocks of proteins but also serve as signaling molecules in multiple biological pathways. The study of adipocytes' response to amino acid level changes is crucial.

Biodegradable Lubricant with High-Temperature and Ionic-Contamination Resistance: Deep Eutectic Solvent ChCl-PEG.

Drilling fluid lubricants guarantee safe and fast drilling. When drilling high-temperature or NaCl/CaCl-containing formations, there is an urgent need to develop environmentally friendly lubricants that are resistant to high temperature and ionic contamination. In this study, a deep eutectic solvent (DES) ChCl-PEG lubricant for a water-based drilling fluid was designed and prepared.

Effective Modified Xanthan Gum Fluid Loss Agent for High-Temperature Water-Based Drilling Fluid and the Filtration Control Mechanism.

Xanthan gum (XG) was widely used as an oilfield chemical treatment agent because of its environmental protection and diverse functions. With the increased drilling depth and formation complexity, the shortcomings such as poor solubility and low resistance to temperature were gradually exposed. In this study, a modified XG derivative XG--AAA was synthesized by grafting XG with acrylic acid (AA), acrylamide (AM), and 2-acrylamido-2-methylpropane sulfonic acid (AMPS).

Effect of inorganic salt on partition of high-polarity parishins in two-phase solvent systems and separation by high-speed counter-current chromatography from Gastrodia elata Blume.

Parishins are high-polarity and major bioactive constituents in Gastrodia elata Blume. In this study, the effect of several inorganic salts on the partition of parishins in two-phase solvent systems was investigated. Adding ammonium sulfate, which has a higher solubility in water, was found to significantly promote the partition of parishins in the upper organic polar solvents.

Effect of plan-do-check-active method combined with air pressure wave therapy on the prevention of deep venous thrombosis in critically ill patients in neurosurgery.

Background: Deep vein thrombosis (DVT) is prone to occur in the recovery of critically ill neurosurgical patients, increasing economic and psychological pressure, and even endangering life. Plan-Do-Check-Action (PDCA) cycle is a kind of quality management cycle procedure, which can help DVT treatment correctly understand the cause of disease and take effective preventive and nursing measures. The air wave pressure therapy instrument takes pressure therapy as the core, forming circulating pressure on limbs and tissues, promoting the flow of blood and lymph, improving the effect of microcirculation, accelerating the return of limb tissue fluid, and preventing thrombosis and limb edema.

Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives.

Aim: To design and synthesize a novel class of antitumor agents, featuring the 3, 5-substituted indolin-2-one framework.

Methods: Based on enzyme binding features of (Z)-SU5402, introducing a beta-pyrrole group at the 3-position of the indolin- 2-one core, a series of novel 3,5-substituted indolin-2-ones were designed and synthesized. Four human carcinoma cell lines of A-431, A-549, MDA-MB-468, and Autosomal Dominant Polycystic Kidney disease were chosen for the cell proliferation assay.