Publications by authors named "Xiufen Ma"
Article Synopsis
- Acne vulgaris affects many young people globally, linked with increased levels of C acnes; concerns about antibiotic resistance push for nonpharmacological treatments like microneedling and postbiotics.
- The study evaluated the effectiveness of a postbiotic formulation alongside microneedling in treating mild-to-moderate facial acne in 20 Chinese patients, focusing on symptom improvement and safety.
- Results indicated significant improvements in acne severity and skin appearance, with high patient satisfaction and no major adverse reactions, suggesting this combination may be a promising alternative for managing acne.
Rechargeable magnesium-metal batteries (RMMBs) are promising next-generation secondary batteries; however, their development is inhibited by the low capacity and short cycle lifespan of cathodes. Although various strategies have been devised to enhance the Mg migration kinetics and structural stability of cathodes, they fail to improve electronic conductivity, rendering the cathodes incompatible with magnesium-metal anodes. Herein, we propose a dual-defect engineering strategy, namely, the incorporation of Mg pre-intercalation defect (P-Mg) and oxygen defect (O), to simultaneously improve the Mg migration kinetics, structural stability, and electronic conductivity of the cathodes of RMMBs.
View Article and Find Full Text PDFMg-ion batteries (MIBs) are promising next-generation secondary batteries, but suffer from sluggish Mg migration kinetics and structural collapse of the cathode materials. Here, an HO-Mg waltz-like shuttle mechanism in the lamellar cathode, which is realized by the coordination, adaptive rotation and flipping, and co-migration of lattice HO molecules with inserted Mg, leading to the fast Mg migration kinetics, is reported; after Mg extraction, the lattice HO molecules rearrange to stabilize the lamellar structure, eliminating structural collapse of the cathode. Consequently, the demo cathode of MgVO·nHO (MVOH) exhibits a high capacity of 350 mAh g at a current density of 50 mA g and maintains a capacity of 70 mAh g at 4 A g.
View Article and Find Full Text PDFRechargeable magnesium batteries (RMBs) suffer from low capacity and poor cyclability of cathode materials, which is due to the sluggish Mg diffusion kinetics and large lattice strain. Here, a layer-interweaving mechanism in lamellar cathode to simultaneously facilitate Mg diffusion and release Mg -insertion strain is reported. In the Cu V O (OH) ·2H O (CVOH) cathode, Mg diffusion highways are generated by the vertical interweaving of CVOH layers and V O layers that nucleate in CVOH during discharging, which are switchable by Mg insertion/extraction.
View Article and Find Full Text PDFWhat Is Known And Objective: Metformin has been suggested to confer anticancer efficacy. However, it remains uncertain whether additional use of metformin could improve survival of women with breast cancer. We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the influence of metformin on survival outcome in women with breast cancer.
View Article and Find Full Text PDFBackground: Long non-coding RNA heart and neural crest derivatives expressed 2-antisense RNA 1 (HAND2-AS1) was found to be elevated in rheumatoid arthritis (RA) fibroblast-like synoviocytes (RA-FLSs). However, whether HAND2-AS1 functions as an exosomal lncRNA related to mesenchymal stem cells (MSCs) in RA progression is unknown.
Methods: The expression of HAND2-AS1, microRNA (miR)-143-3p, and tumor necrosis factor alpha-inducible protein 3 (TNFAIP3) was detected using quantitative real-time polymerase chain reaction and Western blot.
DNA methylation of Interleukin-12B (IL-12B) and miR-34b was proved to affect the expression of IL-12B and miR-34b, which were found to be involved in the pathogenesis of ankylosing spondylitis (AS). However, the molecular mechanisms underlying the role of IL-12B and miR-34b in AS remain to be explored. AS patients were divided into four groups according to their status of DNA methylation of miR-34b and IL-12B by bisulfite sequencing: HYPER-miR-34b + HYPO-IL-12B, HYPER-miR-34b + HYPER-IL-12B, HYPO-miR-34b + HYPER-IL-12B and HYPO-miR-34b + HYPO-IL-12B groups.
View Article and Find Full Text PDFArticle Synopsis
- The researchers conducted a systematic review of gene expression data to find essential genes and functional networks linked to systemic lupus erythematosus (SLE).
- They analyzed datasets from 1,778 SLE patients and 408 healthy controls, using robust rank aggregation and weighted gene coexpression network analysis to identify key genes and functional modules.
- The study highlighted several significant upregulated and downregulated genes, with the main functional module involved in SLE including 182 genes related to viral defense, interferon signaling, and cytokine pathways, offering insights into potential therapeutic targets.
The aim of this study was to explore the correlation of salazosulfamide efficacy on ankylosing spondylitis and N-acetyltransferase 1 () gene polymorphism. Thirty-two patients with ankylosing spondylitis were recruited in the experimental group and 36 normal individuals were recruited to the control group. The experimental group received 8.
View Article and Find Full Text PDF[Role of glucocorticoid receptor in the pathogenesis of systemic lupus erythematosus].
Beijing Da Xue Xue Bao Yi Xue Ban
April 2012
Objective: To investigate the expressions of GRα mRNA and GRβ mRNA in the peripheral blood mononuclear cells (PBMCs) of systemic lupus erythematosus (SLE) patients, in order to reveal the role of GR mRNA in the pathogenesis of SLE and analyze the relationship between GR mRNA and SLEDAI score, dsDNA, cardiovascular involvement.
Methods: Reverse transcription-polymerase chain reaction (RT-PCR) technique was applied to semiquantitatively analyze GRα mRNA and GRβ mRNA expressions in 104 SLE patients and 56 volunteers.
Results: The level of GRα mRNA was lower in the SLE group (the relative level was 1.